Functional MRI Time Series Generation via Wavelet-Based Image Transform and Spectral Flow Matching for Brain Disorder Identification

Functional Magnetic Resonance Imaging (fMRI) provides non-invasive access to dynamic brain activity by measuring blood oxygen level-dependent (BOLD) signals over time. However, the resource-intensive nature of fMRI acquisition limits the availability of high-fidelity samples required for data-driven brain analysis models. While modern generative models can synthesize fMRI data, they often remain challenging in replicating their inherent non-stationarity, intricate spatiotemporal dynamics, and physiological variations of raw BOLD signals. To address these challenges, we propose Dual-Spectral Flow Matching (DSFM), a novel fMRI generative framework that cascades dual frequency representation of BOLD signals with spectral flow matching. Specifically, our framework first converts BOLD signals into a wavelet decomposition map via a discrete wavelet transform (DWT) to capture globalized transient and multi-scale variations, and projects into the discrete cosine transform (DCT) space across brain regions and time to exploit localized energy compaction of low-frequency dominant BOLD coefficients. Subsequently, a spectral flow matching model is trained to generate class-conditioned cosine-frequency representation. The generated samples are reconstructed through inverse DCT and inverse DWT operations to recover physiologically plausible time-domain BOLD signals. This dual-transform approach imposes structured frequency priors and preserves key physiological brain dynamics. Ultimately, we demonstrate the efficacy of our approach through improved downstream fMRI-based brain network classification. The code is available at https://github.com/htew0001/DSFM.git .

Think Fast, Talk Smart: Partitioning Deterministic and Neural Computation for Structured Health Text Generation

Large language models (LLMs) are increasingly being used to generate health text from structured records such as wearable time series, biomarkers, vitals, and care-management logs. For recurring health outputs, fluency is not enough: systems must remain faithful to source data, ground explanatory claims in available evidence, follow stated policies, emit machine-readable outputs, and run cheaply enough for repeated use. We ask which responsibilities in structured health generation should be deterministic computation rather than runtime LLM prompting. We introduce Think Fast, Talk Smart, a sleep-health insight pipeline in which deterministic code performs recurring analysis before one bounded LLM writer call. Across 280 user-nights and six models, achieves lower numeric error, lower instruction-compliance error, and lower end-to-end cost than structured zero-shot and few-shot one-call baselines. Layer replacement reveals contract-specific failures: LLM comparison raises numeric error, LLM ranking degrades policy selection, LLM attribution increases unsupported causal language, and an LLM-generated writer interface reintroduces errors even after upstream facts are deterministic. The results support a broader design rule: let code own recurring analysis, and let LLMs express verified facts within bounded interfaces.

XCTFormer: Leveraging Cross-Channel and Cross-Time Dependencies for Enhanced Time-Series Analysis

Multivariate time-series analysis involves extracting informative representations from sequences of multiple interdependent variables, supporting tasks such as forecasting, imputation, and anomaly detection. In real-world scenarios, these variables are typically collected from a shared context or underlying phenomenon, suggesting the presence of latent dependencies across time and channels that can be leveraged to improve performance. However, recent findings show that channel-independent (CI) models, which assume no inter-variable dependencies, often outperform channel-dependent (CD) models that explicitly model such relationships. This surprising result indicates that current CD models may not fully exploit their potential due to limitations in how dependencies are captured. Recent studies have revisited channel dependence modeling with various approaches; however, these methods often employ indirect modeling strategies, which can lead to meaningful dependencies being overlooked. To address this issue, we introduce XCTFormer, a transformer-based channel-dependent (CD) model that explicitly captures cross-temporal and cross-channel dependencies via an enhanced attention mechanism. The model operates in a token-to-token fashion, modeling pairwise dependencies between every pair of tokens across time and channels. The architecture comprises (i) a data processing module, (ii) a novel Cross-Relational Attention Block (CRAB) that increases capacity and expressiveness, and (iii) an optional Dependency Compression Plugin (DeCoP) that improves scalability. Through extensive experiments on three time-series benchmarks, we show that XCTFormer achieves strong results compared to widely recognized baselines; in particular, it attains state-of-the-art performance on the imputation task, outperforming the second-best method by an average of 20.8% in MSE and 15.3% in MAE.

FHRFormer: A Self-Supervised Masked Transformer Framework for Fetal Heart Rate Time-Series Inpainting and Forecasting

Approximately 10% of newborns require assistance to initiate breathing at birth, and around 5% need ventilation support. Fetal heart rate (FHR) monitoring plays a crucial role in assessing fetal well-being during prenatal care, enabling the detection of abnormal patterns and supporting timely obstetric interventions to mitigate fetal risks during labor. Applying artificial intelligence (AI) methods to analyze large datasets of continuous FHR monitoring episodes with diverse outcomes may offer novel insights into predicting the risk of needing breathing assistance or interventions. Recent advances in wearable FHR monitors have enabled continuous fetal monitoring without compromising maternal mobility. However, sensor displacement during maternal movement, as well as changes in fetal or maternal position, often lead to signal dropout, resulting in gaps in recorded FHR data. Such missing data limits the extraction of meaningful insights and complicates automated (AI-based) analysis. Traditional approaches to handling missing data, such as simple interpolation techniques, often fail to preserve the spectral characteristics of the signals. In this paper, we propose a masked transformer-based autoencoder approach to reconstruct missing FHR signals by capturing both local temporal and frequency components of the data. The proposed method demonstrates robustness across varying durations of missing data and can be used for signal inpainting and forecasting. The proposed approach can be applied retrospectively to research datasets to support the development of AI-based risk algorithms. In the future, the proposed method could be integrated into wearable FHR monitoring devices to achieve earlier and more robust risk detection.

Cycle-Space Informed Detection of Autoencoded Blind False Data Injection Attacks on Power Systems

The rapid growth of AI-driven data centers and large-scale energy storage systems is increasing the reliance of power system operation on real-time measurement data and automated decision-making. However, many existing detection methods rely on statistical or data-driven analysis of measurements and can fail when attackers exploit the same data structure to craft stealthy perturbations. To illustrate this limitation, we demonstrate a blind False Data Injection Attack (FDIA) in which an Autoencoder learns the measurement manifold and generates perturbations aligned with the Jacobian null space, thereby allowing the attack to evade both residual-based baddata detectors and time-series anomaly detectors. To mitigate data-driven FDIAs which exploit the null space, we propose a topology-informed Cycle-Space Detector (CSD) that leverages the Cycle-Space of the network to impose structural constraints that enhance null space estimation. In addition, we prove that by using the Minimum Cycle Basis (MCB), the proposed CSD achieves the optimal generalization error for attack detection. By exploiting topology-derived cycle constraints rather than relying solely on numerical null space estimation, the proposed method does not require precise line parameters and improves the separation between normal and attacked measurements. Simulation results on IEEE 14-, 30-, 57-, and 118-bus systems demonstrate that the proposed method effectively detects data-driven FDIAs under realistic measurement noise.

On the Role of Inductive Bias in Time-Series Pretraining: A Case Study in Learning Generalizable Representations for Clinical Time Series

Clinical time-series learning is routinely constrained by small, heterogeneous cohorts and protocol drift, while its downstream use spans both classification (e.g., pathology diagnosis) and regression (e.g., temporal forecasting). These constraints make foundation-model pretraining appealing, but raises an important question of which inductive biases should the pretraining objective impose so that representations transfer across task types and subjects. We study this question in pathological gait analysis for spinal cord injury (SCI) via PathoFM, an encoder-centric transformer pretrained on multivariate gait windows with three complementary objectives: Local Completion (reconstruct contiguous masked spans to enforce local structure), Temporal Continuity (predict a masked mid-horizon continuation from an observed prefix to enforce smoothness and causal consistency), and Unsupervised In-Context Dynamics (support-query reconstruction conditioned on subject exemplar windows via attention). Empirically comparing objective families (grouping/contrastive, dynamics-based, and generative reconstruction), we find that dynamics-centric mixtures produce the most balanced transfer: grouping objectives favor discriminative margins but can degrade magnitude fidelity needed for continuous targets, whereas reconstruction-only objectives preserve waveform structure but may underperform on classification. Overall, combining local reconstruction with temporal continuity, and adding in-context conditioning when exemplar access is realistic, yields robust subject-generalizing representations.

MULTISEISMO: A Multimodal Seismic Dataset and Model for Cross-Modal Seismic Understanding

The application of generalist multimodal models (GMMs) to specialized scientific domains remains limited due to the scarcity of comprehensive domain-specific datasets that integrate multiple data modalities beyond text and images. In seismology, understanding earthquake phenomena requires the synthesis of timeseries waveform data, geographical imagery, and contextual metadata, a multimodal integration absent in existing seismic datasets. We present MultiSeismo, a large scale structured multimodal seismic dataset, comprising over 16K seismic events spanning 13 years (2010 to 2023) across diverse geographical regions. Each event data integrates waveform recordings from global station networks, intensity maps, population exposure visualizations, and a comprehensive textual description within a standardized JSON format. We additionally develop MISCE, a multimodal instruction set on top of raw data to enable supervised training and evaluation of GMMs on seismic reasoning tasks ranging from basic information retrieval to complex cross modal analysis. We leverage MISCE to finetune an existing multimodal model (Unified IO 2) enhanced with a specialized timeseries encoder, which yields SeisModal, the first domain specific multimodal model for comprehensive seismic analysis. Evaluation of state of the art multimodal models on MultiSeismo reveals significant challenges, particularly with time-series data processing for general purpose models, while demonstrating SeisModal's superior performance on seismic multimodal reasoning tasks. These results prove that MultiSeismo provides a rigorous benchmark for future multimodal research in seismology and validate the success of our domain specific architectural adaptations.

Electricity Consumption Forecasting: An Approach Using Cooperative Ensemble Learning with SHapley Additive exPlanations

Electricity expense management presents significant challenges, as this resource is susceptible to various influencing factors. In universities, the demand for this resource is rapidly growing with institutional expansion and has a significant environmental impact. In this study, the machine learning models long short-term memory (LSTM), random forest (RF), support vector regression (SVR), and extreme gradient boosting (XGBoost) were trained with historical consumption data from the Federal Institute of Paraná (IFPR) over the last seven years and climatic variables to forecast electricity consumption 12 months ahead. Datasets from two campuses were adopted. To improve model performance, feature selection was performed using Shapley additive explanations (SHAP), and hyperparameter optimization was carried out using genetic algorithm (GA) and particle swarm optimization (PSO). The results indicate that the proposed cooperative ensemble learning approach named Weaker Separator Booster (WSB) exhibited the best performance for datasets. Specifically, it achieved an sMAPE of 13.90% and MAE of 1990.87 kWh for the IFPR-Palmas Campus and an sMAPE of 18.72% and MAE of 465.02 kWh for the Coronel Vivida Campus. The SHAP analysis revealed distinct feature importance patterns across the two IFPR campuses. A commonality that emerged was the strong influence of lagged time-series values and a minimal influence of climatic variables.

An Objective Performance Evaluation of the LSTM Networks in Time Series Classification

The rapid adoption of deep learning has increasingly led to data-driven models replacing classical model-based algorithms, even in domains governed by well-understood physical laws. While data-driven models, such as long short-term memory (LSTM) networks, have become a popular choice for time-series analysis, their performance relative to model-based approaches in structured environments is rarely evaluated objectively. This paper presents a performance evaluation framework comparing an LSTM classifier against a model-based expectation maximization (EM) classifier for binary time-series classification. The evaluation is conducted on two scalar linear Gaussian state space models differing only in their noise statistics, where the Kalman filter likelihood ratio test with true parameters serves as a reference for the best achievable classification performance.Through Monte Carlo simulations, the classifiers are evaluated across three axes: task difficulty, controlled by the separation in process or measurement noise between the two models; sequence length; and training dataset size. The results show that the EM classifier, which exploits the known model structure, performs strongly when the data conform to the assumed model class. The LSTM classifier requires a larger separation in noise statistics to achieve reliable classification, and its performance saturates below the reference classifier when the models differ only in measurement noise, regardless of sequence length or training dataset size.

Function-Valued Causal Influence in Nonlinear Time Series

Causal discovery in time series is increasingly performed using nonlinear machine-learning models, yet the resulting causal relationships are almost always summarized by scalar edge scores. We argue that this practice obscures the true object learned by nonlinear autoregressive models: a state-dependent function whose effect varies across regimes, magnitudes, and contexts. We formalize function-valued causal influence for additive, contribution-decomposable architectures and show that scalar causal scores constitute a severe information bottleneck, conflating between-state variation with within-state residual noise. Using Neural Additive Vector Autoregression as a representative architecture, we introduce a practical framework based on Individual Conditional Expectation for estimating causal response functions directly from trained models. Through controlled synthetic experiments, we demonstrate that edges with indistinguishable scalar scores can exhibit qualitatively different functional behaviors, including monotonic, thresholded, saturating, and sign-changing effects. An applied case study on democratic development further shows that function-valued analysis reveals regime-specific and asymmetric causal structure systematically missed by score-centric approaches.