Neutone SDK: An Open Source Framework for Neural Audio Processing

Neural audio processing has unlocked novel methods of sound transformation and synthesis, yet integrating deep learning models into digital audio workstations (DAWs) remains challenging due to real-time / neural network inference constraints and the complexities of plugin development. In this paper, we introduce the Neutone SDK: an open source framework that streamlines the deployment of PyTorch-based neural audio models for both real-time and offline applications. By encapsulating common challenges such as variable buffer sizes, sample rate conversion, delay compensation, and control parameter handling within a unified, model-agnostic interface, our framework enables seamless interoperability between neural models and host plugins while allowing users to work entirely in Python. We provide a technical overview of the interfaces needed to accomplish this, as well as the corresponding SDK implementations. We also demonstrate the SDK's versatility across applications such as audio effect emulation, timbre transfer, and sample generation, as well as its adoption by researchers, educators, companies, and artists alike. The Neutone SDK is available at https://github.com/Neutone/neutone_sdk

Calliope: An Online Generative Music System for Symbolic Multi-Track Composition

With the rise of artificial intelligence in recent years, there has been a rapid increase in its application towards creative domains, including music. There exist many systems built that apply machine learning approaches to the problem of computer-assisted music composition (CAC). Calliope is a web application that assists users in performing a variety of multi-track composition tasks in the symbolic domain. The user can upload (Musical Instrument Digital Interface) MIDI files, visualize and edit MIDI tracks, and generate partial (via bar in-filling) or complete multi-track content using the Multi-Track Music Machine (MMM). Generation of new MIDI excerpts can be done in batch and can be combined with active playback listening for an enhanced assisted-composition workflow. The user can export generated MIDI materials or directly stream MIDI playback from the system to their favorite Digital Audio Workstation (DAW). We present a demonstration of the system, its features, generative parameters and describe the co-creative workflows that it affords.

Evaluating Human-AI Interaction via Usability, User Experience and Acceptance Measures for MMM-C: A Creative AI System for Music Composition

With the rise of artificial intelligence (AI), there has been increasing interest in human-AI co-creation in a variety of artistic domains including music as AI-driven systems are frequently able to generate human-competitive artifacts. Now, the implications of such systems for musical practice are being investigated. We report on a thorough evaluation of the user adoption of the Multi-Track Music Machine (MMM) as a co-creative AI tool for music composers. To do this, we integrate MMM into Cubase, a popular Digital Audio Workstation (DAW) by Steinberg, by producing a "1-parameter" plugin interface named MMM-Cubase (MMM-C), which enables human-AI co-composition. We contribute a methodological assemblage as a 3-part mixed method study measuring usability, user experience and technology acceptance of the system across two groups of expert-level composers: hobbyists and professionals. Results show positive usability and acceptance scores. Users report experiences of novelty, surprise and ease of use from using the system, and limitations on controllability and predictability of the interface when generating music. Findings indicate no significant difference between the two user groups.

Generation of Musical Timbres using a Text-Guided Diffusion Model

In recent years, text-to-audio systems have achieved remarkable success, enabling the generation of complete audio segments directly from text descriptions. While these systems also facilitate music creation, the element of human creativity and deliberate expression is often limited. In contrast, the present work allows composers, arrangers, and performers to create the basic building blocks for music creation: audio of individual musical notes for use in electronic instruments and DAWs. Through text prompts, the user can specify the timbre characteristics of the audio. We introduce a system that combines a latent diffusion model and multi-modal contrastive learning to generate musical timbres conditioned on text descriptions. By jointly generating the magnitude and phase of the spectrogram, our method eliminates the need for subsequently running a phase retrieval algorithm, as related methods do. Audio examples, source code, and a web app are available at https://wxuanyuan.github.io/Musical-Note-Generation/

HARP 2.0: Expanding Hosted, Asynchronous, Remote Processing for Deep Learning in the DAW

HARP 2.0 brings deep learning models to digital audio workstation (DAW) software through hosted, asynchronous, remote processing, allowing users to route audio from a plug-in interface through any compatible Gradio endpoint to perform arbitrary transformations. HARP renders endpoint-defined controls and processed audio in-plugin, meaning users can explore a variety of cutting-edge deep learning models without ever leaving the DAW. In the 2.0 release we introduce support for MIDI-based models and audio/MIDI labeling models, provide a streamlined pyharp Python API for model developers, and implement numerous interface and stability improvements. Through this work, we hope to bridge the gap between model developers and creatives, improving access to deep learning models by seamlessly integrating them into DAW workflows.

PatchCTG: Patch Cardiotocography Transformer for Antepartum Fetal Health Monitoring

Antepartum Cardiotocography (CTG) is vital for fetal health monitoring, but traditional methods like the Dawes-Redman system are often limited by high inter-observer variability, leading to inconsistent interpretations and potential misdiagnoses. This paper introduces PatchCTG, a transformer-based model specifically designed for CTG analysis, employing patch-based tokenisation, instance normalisation and channel-independent processing to capture essential local and global temporal dependencies within CTG signals. PatchCTG was evaluated on the Oxford Maternity (OXMAT) dataset, comprising over 20,000 CTG traces across diverse clinical outcomes after applying the inclusion and exclusion criteria. With extensive hyperparameter optimisation, PatchCTG achieved an AUC of 77%, with specificity of 88% and sensitivity of 57% at Youden's index threshold, demonstrating adaptability to various clinical needs. Testing across varying temporal thresholds showed robust predictive performance, particularly with finetuning on data closer to delivery, achieving a sensitivity of 52% and specificity of 88% for near-delivery cases. These findings suggest the potential of PatchCTG to enhance clinical decision-making in antepartum care by providing a reliable, objective tool for fetal health assessment. The source code is available at https://github.com/jaleedkhan/PatchCTG.

Diff-MSTC: A Mixing Style Transfer Prototype for Cubase

In our demo, participants are invited to explore the Diff-MSTC prototype, which integrates the Diff-MST model into Steinberg's digital audio workstation (DAW), Cubase. Diff-MST, a deep learning model for mixing style transfer, forecasts mixing console parameters for tracks using a reference song. The system processes up to 20 raw tracks along with a reference song to predict mixing console parameters that can be used to create an initial mix. Users have the option to manually adjust these parameters further for greater control. In contrast to earlier deep learning systems that are limited to research ideas, Diff-MSTC is a first-of-its-kind prototype integrated into a DAW. This integration facilitates mixing decisions on multitracks and lets users input context through a reference song, followed by fine-tuning of audio effects in a traditional manner.

Wavespace: A Highly Explorable Wavetable Generator

Wavetable synthesis generates quasi-periodic waveforms of musical tones by interpolating a list of waveforms called wavetable. As generative models that utilize latent representations offer various methods in waveform generation for musical applications, studies in wavetable generation with invertible architecture have also arisen recently. While they are promising, it is still challenging to generate wavetables with detailed controls in disentangling factors within the latent representation. In response, we present Wavespace, a novel framework for wavetable generation that empowers users with enhanced parameter controls. Our model allows users to apply pre-defined conditions to the output wavetables. We employ a variational autoencoder and completely factorize its latent space to different waveform styles. We also condition the generator with auxiliary timbral and morphological descriptors. This way, users can create unique wavetables by independently manipulating each latent subspace and descriptor parameters. Our framework is efficient enough for practical use; we prototyped an oscillator plug-in as a proof of concept for real-time integration of Wavespace within digital audio workspaces (DAWs).

A large parametrized space of meta-reinforcement learning tasks

We describe a parametrized space for simple meta-reinforcement-learning (meta-RL) tasks with arbitrary stimuli. The parametrization allows us to randomly generate an arbitrary number of novel simple meta-learning tasks. The space of meta-RL tasks covered by this parametrization includes many well-known meta-RL tasks, such as bandit tasks, the Harlow task, T-mazes, the Daw two-step task and others. Simple extensions allow it to capture tasks based on two-dimensional topological spaces, such as find-the-spot or key-door tasks. We describe a number of randomly generated meta-RL tasks and discuss potential issues arising from random generation.

Learning Robust Representation for Joint Grading of Ophthalmic Diseases via Adaptive Curriculum and Feature Disentanglement

Diabetic retinopathy (DR) and diabetic macular edema (DME) are leading causes of permanent blindness worldwide. Designing an automatic grading system with good generalization ability for DR and DME is vital in clinical practice. However, prior works either grade DR or DME independently, without considering internal correlations between them, or grade them jointly by shared feature representation, yet ignoring potential generalization issues caused by difficult samples and data bias. Aiming to address these problems, we propose a framework for joint grading with the dynamic difficulty-aware weighted loss (DAW) and the dual-stream disentangled learning architecture (DETACH). Inspired by curriculum learning, DAW learns from simple samples to difficult samples dynamically via measuring difficulty adaptively. DETACH separates features of grading tasks to avoid potential emphasis on the bias. With the addition of DAW and DETACH, the model learns robust disentangled feature representations to explore internal correlations between DR and DME and achieve better grading performance. Experiments on three benchmarks show the effectiveness and robustness of our framework under both the intra-dataset and cross-dataset tests.