Mirror: A Multi-Agent System for AI-Assisted Ethics Review

Ethics review is a foundational mechanism of modern research governance, yet contemporary systems face increasing strain as ethical risks arise as structural consequences of large-scale, interdisciplinary scientific practice. The demand for consistent and defensible decisions under heterogeneous risk profiles exposes limitations in institutional review capacity rather than in the legitimacy of ethics oversight. Recent advances in large language models (LLMs) offer new opportunities to support ethics review, but their direct application remains limited by insufficient ethical reasoning capability, weak integration with regulatory structures, and strict privacy constraints on authentic review materials. In this work, we introduce Mirror, an agentic framework for AI-assisted ethical review that integrates ethical reasoning, structured rule interpretation, and multi-agent deliberation within a unified architecture. At its core is EthicsLLM, a foundational model fine-tuned on EthicsQA, a specialized dataset of 41K question-chain-of-thought-answer triples distilled from authoritative ethics and regulatory corpora. EthicsLLM provides detailed normative and regulatory understanding, enabling Mirror to operate in two complementary modes. Mirror-ER (expedited Review) automates expedited review through an executable rule base that supports efficient and transparent compliance checks for minimal-risk studies. Mirror-CR (Committee Review) simulates full-board deliberation through coordinated interactions among expert agents, an ethics secretary agent, and a principal investigator agent, producing structured, committee-level assessments across ten ethical dimensions. Empirical evaluations demonstrate that Mirror significantly improves the quality, consistency, and professionalism of ethics assessments compared with strong generalist LLMs.

Federated Linear Dueling Bandits

Contextual linear dueling bandits have recently garnered significant attention due to their widespread applications in important domains such as recommender systems and large language models. Classical dueling bandit algorithms are typically only applicable to a single agent. However, many applications of dueling bandits involve multiple agents who wish to collaborate for improved performance yet are unwilling to share their data. This motivates us to draw inspirations from federated learning, which involves multiple agents aiming to collaboratively train their neural networks via gradient descent (GD) without sharing their raw data. Previous works have developed federated linear bandit algorithms which rely on closed-form updates of the bandit parameters (e.g., the linear function parameter) to achieve collaboration. However, in linear dueling bandits, the linear function parameter lacks a closed-form expression and its estimation requires minimizing a loss function. This renders these previous methods inapplicable. In this work, we overcome this challenge through an innovative and principled combination of online gradient descent (for minimizing the loss function to estimate the linear function parameters) and federated learning, hence introducing the first federated linear dueling bandit algorithms. Through rigorous theoretical analysis, we prove that our algorithms enjoy a sub-linear upper bound on its cumulative regret. We also use empirical experiments to demonstrate the effectiveness of our algorithms and the practical benefit of collaboration.