Abstract:Accurate classification of sleep stages based on bio-signals is fundamental for automatic sleep stage annotation. Traditionally, this task relies on experienced clinicians to manually annotate data, a process that is both time-consuming and labor-intensive. In recent years, deep learning methods have shown promise in automating this task. However, three major challenges remain: (1) deep learning models typically require large-scale labeled datasets, making them less effective in real-world settings where annotated data is limited; (2) significant inter-individual variability in bio-signals often results in inconsistent model performance when applied to new subjects, limiting generalization; and (3) existing approaches often overlook the high-order relationships among bio-signals, failing to simultaneously capture signal heterogeneity and spatial-temporal dependencies. To address these issues, we propose MetaSTH-Sleep, a few-shot sleep stage classification framework based on spatial-temporal hypergraph enhanced meta-learning. Our approach enables rapid adaptation to new subjects using only a few labeled samples, while the hypergraph structure effectively models complex spatial interconnections and temporal dynamics simultaneously in EEG signals. Experimental results demonstrate that MetaSTH-Sleep achieves substantial performance improvements across diverse subjects, offering valuable insights to support clinicians in sleep stage annotation.