Exhaustive Exploitation of Nature-inspired Computation for Cancer Screening in an Ensemble Manner

Accurate screening of cancer types is crucial for effective cancer detection and precise treatment selection. However, the association between gene expression profiles and tumors is often limited to a small number of biomarker genes. While computational methods using nature-inspired algorithms have shown promise in selecting predictive genes, existing techniques are limited by inefficient search and poor generalization across diverse datasets. This study presents a framework termed Evolutionary Optimized Diverse Ensemble Learning (EODE) to improve ensemble learning for cancer classification from gene expression data. The EODE methodology combines an intelligent grey wolf optimization algorithm for selective feature space reduction, guided random injection modeling for ensemble diversity enhancement, and subset model optimization for synergistic classifier combinations. Extensive experiments were conducted across 35 gene expression benchmark datasets encompassing varied cancer types. Results demonstrated that EODE obtained significantly improved screening accuracy over individual and conventionally aggregated models. The integrated optimization of advanced feature selection, directed specialized modeling, and cooperative classifier ensembles helps address key challenges in current nature-inspired approaches. This provides an effective framework for robust and generalized ensemble learning with gene expression biomarkers. Specifically, we have opened EODE source code on Github at https://github.com/wangxb96/EODE.

MEL: Efficient Multi-Task Evolutionary Learning for High-Dimensional Feature Selection

Feature selection is a crucial step in data mining to enhance model performance by reducing data dimensionality. However, the increasing dimensionality of collected data exacerbates the challenge known as the "curse of dimensionality", where computation grows exponentially with the number of dimensions. To tackle this issue, evolutionary computational (EC) approaches have gained popularity due to their simplicity and applicability. Unfortunately, the diverse designs of EC methods result in varying abilities to handle different data, often underutilizing and not sharing information effectively. In this paper, we propose a novel approach called PSO-based Multi-task Evolutionary Learning (MEL) that leverages multi-task learning to address these challenges. By incorporating information sharing between different feature selection tasks, MEL achieves enhanced learning ability and efficiency. We evaluate the effectiveness of MEL through extensive experiments on 22 high-dimensional datasets. Comparing against 24 EC approaches, our method exhibits strong competitiveness. Additionally, we have open-sourced our code on GitHub at https://github.com/wangxb96/MEL.

A Self-adaptive Weighted Differential Evolution Approach for Large-scale Feature Selection

Recently, many evolutionary computation methods have been developed to solve the feature selection problem. However, the studies focused mainly on small-scale issues, resulting in stagnation issues in local optima and numerical instability when dealing with large-scale feature selection dilemmas. To address these challenges, this paper proposes a novel weighted differential evolution algorithm based on self-adaptive mechanism, named SaWDE, to solve large-scale feature selection. First, a multi-population mechanism is adopted to enhance the diversity of the population. Then, we propose a new self-adaptive mechanism that selects several strategies from a strategy pool to capture the diverse characteristics of the datasets from the historical information. Finally, a weighted model is designed to identify the important features, which enables our model to generate the most suitable feature-selection solution. We demonstrate the effectiveness of our algorithm on twelve large-scale datasets. The performance of SaWDE is superior compared to six non-EC algorithms and six other EC algorithms, on both training and test datasets and on subset size, indicating that our algorithm is a favorable tool to solve the large-scale feature selection problem. Moreover, we have experimented SaWDE with six EC algorithms on twelve higher-dimensional data, which demonstrates that SaWDE is more robust and efficient compared to those state-of-the-art methods. SaWDE source code is available on Github at https://github.com/wangxb96/SaWDE.

Research on facial expression recognition based on Multimodal data fusion and neural network

Facial expression recognition is a challenging task when neural network is applied to pattern recognition. Most of the current recognition research is based on single source facial data, which generally has the disadvantages of low accuracy and low robustness. In this paper, a neural network algorithm of facial expression recognition based on multimodal data fusion is proposed. The algorithm is based on the multimodal data, and it takes the facial image, the histogram of oriented gradient of the image and the facial landmarks as the input, and establishes CNN, LNN and HNN three sub neural networks to extract data features, using multimodal data feature fusion mechanism to improve the accuracy of facial expression recognition. Experimental results show that, benefiting by the complementarity of multimodal data, the algorithm has a great improvement in accuracy, robustness and detection speed compared with the traditional facial expression recognition algorithm. Especially in the case of partial occlusion, illumination and head posture transformation, the algorithm also shows a high confidence.