IntelliCardiac: An Intelligent Platform for Cardiac Image Segmentation and Classification

Precise and effective processing of cardiac imaging data is critical for the identification and management of the cardiovascular diseases. We introduce IntelliCardiac, a comprehensive, web-based medical image processing platform for the automatic segmentation of 4D cardiac images and disease classification, utilizing an AI model trained on the publicly accessible ACDC dataset. The system, intended for patients, cardiologists, and healthcare professionals, offers an intuitive interface and uses deep learning models to identify essential heart structures and categorize cardiac diseases. The system supports analysis of both the right and left ventricles as well as myocardium, and then classifies patient's cardiac images into five diagnostic categories: dilated cardiomyopathy, myocardial infarction, hypertrophic cardiomyopathy, right ventricular abnormality, and no disease. IntelliCardiac combines a deep learning-based segmentation model with a two-step classification pipeline. The segmentation module gains an overall accuracy of 92.6%. The classification module, trained on characteristics taken from segmented heart structures, achieves 98% accuracy in five categories. These results exceed the performance of the existing state-of-the-art methods that integrate both segmentation and classification models. IntelliCardiac, which supports real-time visualization, workflow integration, and AI-assisted diagnostics, has great potential as a scalable, accurate tool for clinical decision assistance in cardiac imaging and diagnosis.

UU-Mamba: Uncertainty-aware U-Mamba for Cardiac Image Segmentation

Biomedical image segmentation is critical for accurate identification and analysis of anatomical structures in medical imaging, particularly in cardiac MRI. However, manual segmentation is labor-intensive, time-consuming, and prone to variability, necessitating automated methods. Current machine learning approaches, while promising, face challenges such as overfitting, high computational demands, and the need for extensive annotated data. To address these issues, we propose a UU-Mamba model that integrates the U-Mamba model with the Sharpness-Aware Minimization optimizer and an uncertainty-aware loss function. SAM enhances generalization by finding flat minima in the loss landscape, mitigating overfitting. The uncertainty-aware loss combines region-based, distribution-based, and pixel-based losses, improving segmentation accuracy and robustness. Our method, evaluated on the ACDC cardiac dataset, outperforms state-of-the-art models (TransUNet, Swin-Unet, nnUNet, nnFormer), achieving superior Dice Similarity Coefficient and Mean Squared Error results, demonstrating the effectiveness of our approach in cardiac MRI segmentation.