Not Only Grey Matter: OmniBrain for Robust Multimodal Classification of Alzheimer's Disease

Alzheimer's disease affects over 55 million people worldwide and is projected to more than double by 2050, necessitating rapid, accurate, and scalable diagnostics. However, existing approaches are limited because they cannot achieve clinically acceptable accuracy, generalization across datasets, robustness to missing modalities, and explainability all at the same time. This inability to satisfy all these requirements simultaneously undermines their reliability in clinical settings. We propose OmniBrain, a multimodal framework that integrates brain MRI, radiomics, gene expression, and clinical data using a unified model with cross-attention and modality dropout. OmniBrain achieves $92.2 \pm 2.4\%$accuracy on the ANMerge dataset and generalizes to the MRI-only ADNI dataset with $70.4 \pm 2.7\%$ accuracy, outperforming unimodal and prior multimodal approaches. Explainability analyses highlight neuropathologically relevant brain regions and genes, enhancing clinical trust. OmniBrain offers a robust, interpretable, and practical solution for real-world Alzheimer's diagnosis.

Khattat: Enhancing Readability and Concept Representation of Semantic Typography

Designing expressive typography that visually conveys a word's meaning while maintaining readability is a complex task, known as semantic typography. It involves selecting an idea, choosing an appropriate font, and balancing creativity with legibility. We introduce an end-to-end system that automates this process. First, a Large Language Model (LLM) generates imagery ideas for the word, useful for abstract concepts like freedom. Then, the FontCLIP pre-trained model automatically selects a suitable font based on its semantic understanding of font attributes. The system identifies optimal regions of the word for morphing and iteratively transforms them using a pre-trained diffusion model. A key feature is our OCR-based loss function, which enhances readability and enables simultaneous stylization of multiple characters. We compare our method with other baselines, demonstrating great readability enhancement and versatility across multiple languages and writing scripts.