Not Only Grey Matter: OmniBrain for Robust Multimodal Classification of Alzheimer's Disease

Alzheimer's disease affects over 55 million people worldwide and is projected to more than double by 2050, necessitating rapid, accurate, and scalable diagnostics. However, existing approaches are limited because they cannot achieve clinically acceptable accuracy, generalization across datasets, robustness to missing modalities, and explainability all at the same time. This inability to satisfy all these requirements simultaneously undermines their reliability in clinical settings. We propose OmniBrain, a multimodal framework that integrates brain MRI, radiomics, gene expression, and clinical data using a unified model with cross-attention and modality dropout. OmniBrain achieves $92.2 \pm 2.4\%$accuracy on the ANMerge dataset and generalizes to the MRI-only ADNI dataset with $70.4 \pm 2.7\%$ accuracy, outperforming unimodal and prior multimodal approaches. Explainability analyses highlight neuropathologically relevant brain regions and genes, enhancing clinical trust. OmniBrain offers a robust, interpretable, and practical solution for real-world Alzheimer's diagnosis.

GeoLLaVA: Efficient Fine-Tuned Vision-Language Models for Temporal Change Detection in Remote Sensing

Detecting temporal changes in geographical landscapes is critical for applications like environmental monitoring and urban planning. While remote sensing data is abundant, existing vision-language models (VLMs) often fail to capture temporal dynamics effectively. This paper addresses these limitations by introducing an annotated dataset of video frame pairs to track evolving geographical patterns over time. Using fine-tuning techniques like Low-Rank Adaptation (LoRA), quantized LoRA (QLoRA), and model pruning on models such as Video-LLaVA and LLaVA-NeXT-Video, we significantly enhance VLM performance in processing remote sensing temporal changes. Results show significant improvements, with the best performance achieving a BERT score of 0.864 and ROUGE-1 score of 0.576, demonstrating superior accuracy in describing land-use transformations.