History Rhymes: Macro-Contextual Retrieval for Robust Financial Forecasting

Financial markets are inherently non-stationary: structural breaks and macroeconomic regime shifts often cause forecasting models to fail when deployed out of distribution (OOD). Conventional multimodal approaches that simply fuse numerical indicators and textual sentiment rarely adapt to such shifts. We introduce macro-contextual retrieval, a retrieval-augmented forecasting framework that grounds each prediction in historically analogous macroeconomic regimes. The method jointly embeds macro indicators (e.g., CPI, unemployment, yield spread, GDP growth) and financial news sentiment in a shared similarity space, enabling causal retrieval of precedent periods during inference without retraining. Trained on seventeen years of S&P 500 data (2007-2023) and evaluated OOD on AAPL (2024) and XOM (2024), the framework consistently narrows the CV to OOD performance gap. Macro-conditioned retrieval achieves the only positive out-of-sample trading outcomes (AAPL: PF=1.18, Sharpe=0.95; XOM: PF=1.16, Sharpe=0.61), while static numeric, text-only, and naive multimodal baselines collapse under regime shifts. Beyond metric gains, retrieved neighbors form interpretable evidence chains that correspond to recognizable macro contexts, such as inflationary or yield-curve inversion phases, supporting causal interpretability and transparency. By operationalizing the principle that "financial history may not repeat, but it often rhymes," this work demonstrates that macro-aware retrieval yields robust, explainable forecasts under distributional change. All datasets, models, and source code are publicly available.

From Retinal Pixels to Patients: Evolution of Deep Learning Research in Diabetic Retinopathy Screening

Diabetic Retinopathy (DR) remains a leading cause of preventable blindness, with early detection critical for reducing vision loss worldwide. Over the past decade, deep learning has transformed DR screening, progressing from early convolutional neural networks trained on private datasets to advanced pipelines addressing class imbalance, label scarcity, domain shift, and interpretability. This survey provides the first systematic synthesis of DR research spanning 2016-2025, consolidating results from 50+ studies and over 20 datasets. We critically examine methodological advances, including self- and semi-supervised learning, domain generalization, federated training, and hybrid neuro-symbolic models, alongside evaluation protocols, reporting standards, and reproducibility challenges. Benchmark tables contextualize performance across datasets, while discussion highlights open gaps in multi-center validation and clinical trust. By linking technical progress with translational barriers, this work outlines a practical agenda for reproducible, privacy-preserving, and clinically deployable DR AI. Beyond DR, many of the surveyed innovations extend broadly to medical imaging at scale.

How Small Can You Go? Compact Language Models for On-Device Critical Error Detection in Machine Translation

Large Language Models (LLMs) excel at evaluating machine translation (MT), but their scale and cost hinder deployment on edge devices and in privacy-sensitive workflows. We ask: how small can you get while still detecting meaning-altering translation errors? Focusing on English->German Critical Error Detection (CED), we benchmark sub-2B models (LFM2-350M, Qwen-3-0.6B/1.7B, Llama-3.2-1B-Instruct, Gemma-3-1B) across WMT21, WMT22, and SynCED-EnDe-2025. Our framework standardizes prompts, applies lightweight logit-bias calibration and majority voting, and reports both semantic quality (MCC, F1-ERR/F1-NOT) and compute metrics (VRAM, latency, throughput). Results reveal a clear sweet spot around one billion parameters: Gemma-3-1B provides the best quality-efficiency trade-off, reaching MCC=0.77 with F1-ERR=0.98 on SynCED-EnDe-2025 after merged-weights fine-tuning, while maintaining 400 ms single-sample latency on a MacBook Pro M4 Pro (24 GB). At larger scale, Qwen-3-1.7B attains the highest absolute MCC (+0.11 over Gemma) but with higher compute cost. In contrast, ultra-small models (0.6B) remain usable with few-shot calibration yet under-detect entity and number errors. Overall, compact, instruction-tuned LLMs augmented with lightweight calibration and small-sample supervision can deliver trustworthy, on-device CED for MT, enabling private, low-cost error screening in real-world translation pipelines. All datasets, prompts, and scripts are publicly available at our GitHub repository.

Reasoning LLMs in the Medical Domain: A Literature Survey

The emergence of advanced reasoning capabilities in Large Language Models (LLMs) marks a transformative development in healthcare applications. Beyond merely expanding functional capabilities, these reasoning mechanisms enhance decision transparency and explainability-critical requirements in medical contexts. This survey examines the transformation of medical LLMs from basic information retrieval tools to sophisticated clinical reasoning systems capable of supporting complex healthcare decisions. We provide a thorough analysis of the enabling technological foundations, with a particular focus on specialized prompting techniques like Chain-of-Thought and recent breakthroughs in Reinforcement Learning exemplified by DeepSeek-R1. Our investigation evaluates purpose-built medical frameworks while also examining emerging paradigms such as multi-agent collaborative systems and innovative prompting architectures. The survey critically assesses current evaluation methodologies for medical validation and addresses persistent challenges in field interpretation limitations, bias mitigation strategies, patient safety frameworks, and integration of multimodal clinical data. Through this survey, we seek to establish a roadmap for developing reliable LLMs that can serve as effective partners in clinical practice and medical research.