Ontology- and LLM-based Data Harmonization for Federated Learning in Healthcare

The rise of electronic health records (EHRs) has unlocked new opportunities for medical research, but privacy regulations and data heterogeneity remain key barriers to large-scale machine learning. Federated learning (FL) enables collaborative modeling without sharing raw data, yet faces challenges in harmonizing diverse clinical datasets. This paper presents a two-step data alignment strategy integrating ontologies and large language models (LLMs) to support secure, privacy-preserving FL in healthcare, demonstrating its effectiveness in a real-world project involving semantic mapping of EHR data.

Transformer-Empowered Actor-Critic Reinforcement Learning for Sequence-Aware Service Function Chain Partitioning

In the forthcoming era of 6G networks, characterized by unprecedented data rates, ultra-low latency, and extensive connectivity, effective management of Virtualized Network Functions (VNFs) is essential. VNFs are software-based counterparts of traditional hardware devices that facilitate flexible and scalable service provisioning. Service Function Chains (SFCs), structured as ordered sequences of VNFs, are pivotal in orchestrating complex network services. Nevertheless, partitioning SFCs across multi-domain network infrastructures presents substantial challenges due to stringent latency constraints and limited resource availability. Conventional optimization-based methods typically exhibit low scalability, whereas existing data-driven approaches often fail to adequately balance computational efficiency with the capability to effectively account for dependencies inherent in SFCs. To overcome these limitations, we introduce a Transformer-empowered actor-critic framework specifically designed for sequence-aware SFC partitioning. By utilizing the self-attention mechanism, our approach effectively models complex inter-dependencies among VNFs, facilitating coordinated and parallelized decision-making processes. Additionally, we enhance training stability and convergence using $\epsilon$-LoPe exploration strategy as well as Asymptotic Return Normalization. Comprehensive simulation results demonstrate that the proposed methodology outperforms existing state-of-the-art solutions in terms of long-term acceptance rates, resource utilization efficiency, and scalability, while achieving rapid inference. This study not only advances intelligent network orchestration by delivering a scalable and robust solution for SFC partitioning within emerging 6G environments, but also bridging recent advancements in Large Language Models (LLMs) with the optimization of next-generation networks.

RAILS: Risk-Aware Iterated Local Search for Joint SLA Decomposition and Service Provider Management in Multi-Domain Networks

The emergence of the fifth generation (5G) technology has transformed mobile networks into multi-service environments, necessitating efficient network slicing to meet diverse Service Level Agreements (SLAs). SLA decomposition across multiple network domains, each potentially managed by different service providers, poses a significant challenge due to limited visibility into real-time underlying domain conditions. This paper introduces Risk-Aware Iterated Local Search (RAILS), a novel risk model-driven meta-heuristic framework designed to jointly address SLA decomposition and service provider selection in multi-domain networks. By integrating online risk modeling with iterated local search principles, RAILS effectively navigates the complex optimization landscape, utilizing historical feedback from domain controllers. We formulate the joint problem as a Mixed-Integer Nonlinear Programming (MINLP) problem and prove its NP-hardness. Extensive simulations demonstrate that RAILS achieves near-optimal performance, offering an efficient, real-time solution for adaptive SLA management in modern multi-domain networks.

PriCE: Privacy-Preserving and Cost-Effective Scheduling for Parallelizing the Large Medical Image Processing Workflow over Hybrid Clouds

Running deep neural networks for large medical images is a resource-hungry and time-consuming task with centralized computing. Outsourcing such medical image processing tasks to hybrid clouds has benefits, such as a significant reduction of execution time and monetary cost. However, due to privacy concerns, it is still challenging to process sensitive medical images over clouds, which would hinder their deployment in many real-world applications. To overcome this, we first formulate the overall optimization objectives of the privacy-preserving distributed system model, i.e., minimizing the amount of information about the private data learned by the adversaries throughout the process, reducing the maximum execution time and cost under the user budget constraint. We propose a novel privacy-preserving and cost-effective method called PriCE to solve this multi-objective optimization problem. We performed extensive simulation experiments for artifact detection tasks on medical images using an ensemble of five deep convolutional neural network inferences as the workflow task. Experimental results show that PriCE successfully splits a wide range of input gigapixel medical images with graph-coloring-based strategies, yielding desired output utility and lowering the privacy risk, makespan, and monetary cost under user's budget.

Adaptive Services Function Chain Orchestration For Digital Health Twin Use Cases: Heuristic-boosted Q-Learning Approach

Digital Twin (DT) is a prominent technology to utilise and deploy within the healthcare sector. Yet, the main challenges facing such applications are: Strict health data-sharing policies, high-performance network requirements, and possible infrastructure resource limitations. In this paper, we address all the challenges by provisioning adaptive Virtual Network Functions (VNFs) to enforce security policies associated with different data-sharing scenarios. We define a Cloud-Native Network orchestrator on top of a multi-node cluster mesh infrastructure for flexible and dynamic container scheduling. The proposed framework considers the intended data-sharing use case, the policies associated, and infrastructure configurations, then provision Service Function Chaining (SFC) and provides routing configurations accordingly with little to no human intervention. Moreover, what is \textit{optimal} when deploying SFC is dependent on the use case itself, and we tune the hyperparameters to prioritise resource utilisation or latency in an effort to comply with the performance requirements. As a result, we provide an adaptive network orchestration for digital health twin use cases, that is policy-aware, requirements-aware, and resource-aware.

V2N Service Scaling with Deep Reinforcement Learning

The fifth generation (5G) of wireless networks is set out to meet the stringent requirements of vehicular use cases. Edge computing resources can aid in this direction by moving processing closer to end-users, reducing latency. However, given the stochastic nature of traffic loads and availability of physical resources, appropriate auto-scaling mechanisms need to be employed to support cost-efficient and performant services. To this end, we employ Deep Reinforcement Learning (DRL) for vertical scaling in Edge computing to support vehicular-to-network communications. We address the problem using Deep Deterministic Policy Gradient (DDPG). As DDPG is a model-free off-policy algorithm for learning continuous actions, we introduce a discretization approach to support discrete scaling actions. Thus we address scalability problems inherent to high-dimensional discrete action spaces. Employing a real-world vehicular trace data set, we show that DDPG outperforms existing solutions, reducing (at minimum) the average number of active CPUs by 23% while increasing the long-term reward by 24%.