Beyond Instance-Level Self-Supervision in 3D Multi-Modal Medical Imaging

Self-supervised pre-training methods in medical imaging typically treat each individual as an isolated instance, learning representations through augmentation-based objectives or masked reconstruction. They often do not adequately capitalize on a key characteristic of physiological features: anatomical structures maintain consistent spatial relationships across individuals (instances), such as the thalamus being medial to the basal ganglia, regardless of variations in brain size, shape, or pathology. We propose leveraging this cross-instance topological consistency as a supervisory signal. The challenge arises from the inherent variability in medical imaging, which can differ significantly across instances and modalities. To tackle this, we focus on two alignment regimes. (i) Intra-instance: with pixel-level correspondences available, a cross-modal triplet objective explicitly preserves local neighborhood topology. (ii) Inter-instance: without such supervision, we derive pseudo-correspondences to control partial neighborhood alignment and prevent topology collapse across modalities. We validate our approach across 7 downstream multi-modal tasks, achieving average improvements of 1.1% and 5.94% in segmentation and classification tasks, respectively, and demonstrating significantly better robustness when modalities are missing at test time.

Soften the Mask: Adaptive Temporal Soft Mask for Efficient Dynamic Facial Expression Recognition

Dynamic Facial Expression Recognition (DFER) facilitates the understanding of psychological intentions through non-verbal communication. Existing methods struggle to manage irrelevant information, such as background noise and redundant semantics, which impacts both efficiency and effectiveness. In this work, we propose a novel supervised temporal soft masked autoencoder network for DFER, namely AdaTosk, which integrates a parallel supervised classification branch with the self-supervised reconstruction branch. The self-supervised reconstruction branch applies random binary hard mask to generate diverse training samples, encouraging meaningful feature representations in visible tokens. Meanwhile the classification branch employs an adaptive temporal soft mask to flexibly mask visible tokens based on their temporal significance. Its two key components, respectively of, class-agnostic and class-semantic soft masks, serve to enhance critical expression moments and reduce semantic redundancy over time. Extensive experiments conducted on widely-used benchmarks demonstrate that our AdaTosk remarkably reduces computational costs compared with current state-of-the-art methods while still maintaining competitive performance.