Patient Similarity Computation for Clinical Decision Support: An Efficient Use of Data Transformation, Combining Static and Time Series Data

Patient similarity computation (PSC) is a fundamental problem in healthcare informatics. The aim of the patient similarity computation is to measure the similarity among patients according to their historical clinical records, which helps to improve clinical decision support. This paper presents a novel distributed patient similarity computation (DPSC) technique based on data transformation (DT) methods, utilizing an effective combination of time series and static data. Time series data are sensor-collected patients' information, including metrics like heart rate, blood pressure, Oxygen saturation, respiration, etc. The static data are mainly patient background and demographic data, including age, weight, height, gender, etc. Static data has been used for clustering the patients. Before feeding the static data to the machine learning model adaptive Weight-of-Evidence (aWOE) and Z-score data transformation (DT) methods have been performed, which improve the prediction performances. In aWOE-based patient similarity models, sensitive patient information has been processed using aWOE which preserves the data privacy of the trained models. We used the Dynamic Time Warping (DTW) approach, which is robust and very popular, for time series similarity. However, DTW is not suitable for big data due to the significant computational run-time. To overcome this problem, distributed DTW computation is used in this study. For Coronary Artery Disease, our DT based approach boosts prediction performance by as much as 11.4%, 10.20%, and 12.6% in terms of AUC, accuracy, and F-measure, respectively. In the case of Congestive Heart Failure (CHF), our proposed method achieves performance enhancement up to 15.9%, 10.5%, and 21.9% for the same measures, respectively. The proposed method reduces the computation time by as high as 40%.

Inceptive Transformers: Enhancing Contextual Representations through Multi-Scale Feature Learning Across Domains and Languages

Conventional transformer models typically compress the information from all tokens in a sequence into a single \texttt{[CLS]} token to represent global context-- an approach that can lead to information loss in tasks requiring localized or hierarchical cues. In this work, we introduce \textit{Inceptive Transformer}, a modular and lightweight architecture that enriches transformer-based token representations by integrating a multi-scale feature extraction module inspired by inception networks. Our model is designed to balance local and global dependencies by dynamically weighting tokens based on their relevance to a particular task. Evaluation across a diverse range of tasks including emotion recognition (both English and Bangla), irony detection, disease identification, and anti-COVID vaccine tweets classification shows that our models consistently outperform the baselines by 1\% to 14\% while maintaining efficiency. These findings highlight the versatility and cross-lingual applicability of our method for enriching transformer-based representations across diverse domains.

Privacy-Preserving Customer Churn Prediction Model in the Context of Telecommunication Industry

Data is the main fuel of a successful machine learning model. A dataset may contain sensitive individual records e.g. personal health records, financial data, industrial information, etc. Training a model using this sensitive data has become a new privacy concern when someone uses third-party cloud computing. Trained models also suffer privacy attacks which leads to the leaking of sensitive information of the training data. This study is conducted to preserve the privacy of training data in the context of customer churn prediction modeling for the telecommunications industry (TCI). In this work, we propose a framework for privacy-preserving customer churn prediction (PPCCP) model in the cloud environment. We have proposed a novel approach which is a combination of Generative Adversarial Networks (GANs) and adaptive Weight-of-Evidence (aWOE). Synthetic data is generated from GANs, and aWOE is applied on the synthetic training dataset before feeding the data to the classification algorithms. Our experiments were carried out using eight different machine learning (ML) classifiers on three openly accessible datasets from the telecommunication sector. We then evaluated the performance using six commonly employed evaluation metrics. In addition to presenting a data privacy analysis, we also performed a statistical significance test. The training and prediction processes achieve data privacy and the prediction classifiers achieve high prediction performance (87.1\% in terms of F-Measure for GANs-aWOE based Na\"{\i}ve Bayes model). In contrast to earlier studies, our suggested approach demonstrates a prediction enhancement of up to 28.9\% and 27.9\% in terms of accuracy and F-measure, respectively.

PULSAR: Graph based Positive Unlabeled Learning with Multi Stream Adaptive Convolutions for Parkinson's Disease Recognition

Parkinson's disease (PD) is a neuro-degenerative disorder that affects movement, speech, and coordination. Timely diagnosis and treatment can improve the quality of life for PD patients. However, access to clinical diagnosis is limited in low and middle income countries (LMICs). Therefore, development of automated screening tools for PD can have a huge social impact, particularly in the public health sector. In this paper, we present PULSAR, a novel method to screen for PD from webcam-recorded videos of the finger-tapping task from the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS). PULSAR is trained and evaluated on data collected from 382 participants (183 self-reported as PD patients). We used an adaptive graph convolutional neural network to dynamically learn the spatio temporal graph edges specific to the finger-tapping task. We enhanced this idea with a multi stream adaptive convolution model to learn features from different modalities of data critical to detect PD, such as relative location of the finger joints, velocity and acceleration of tapping. As the labels of the videos are self-reported, there could be cases of undiagnosed PD in the non-PD labeled samples. We leveraged the idea of Positive Unlabeled (PU) Learning that does not need labeled negative data. Our experiments show clear benefit of modeling the problem in this way. PULSAR achieved 80.95% accuracy in validation set and a mean accuracy of 71.29% (2.49% standard deviation) in independent test, despite being trained with limited amount of data. This is specially promising as labeled data is scarce in health care sector. We hope PULSAR will make PD screening more accessible to everyone. The proposed techniques could be extended for assessment of other movement disorders, such as ataxia, and Huntington's disease.

Unmasking Parkinson's Disease with Smile: An AI-enabled Screening Framework

Parkinson's disease (PD) diagnosis remains challenging due to lacking a reliable biomarker and limited access to clinical care. In this study, we present an analysis of the largest video dataset containing micro-expressions to screen for PD. We collected 3,871 videos from 1,059 unique participants, including 256 self-reported PD patients. The recordings are from diverse sources encompassing participants' homes across multiple countries, a clinic, and a PD care facility in the US. Leveraging facial landmarks and action units, we extracted features relevant to Hypomimia, a prominent symptom of PD characterized by reduced facial expressions. An ensemble of AI models trained on these features achieved an accuracy of 89.7% and an Area Under the Receiver Operating Characteristic (AUROC) of 89.3% while being free from detectable bias across population subgroups based on sex and ethnicity on held-out data. Further analysis reveals that features from the smiling videos alone lead to comparable performance, even on two external test sets the model has never seen during training, suggesting the potential for PD risk assessment from smiling selfie videos.