Abstract:Zero-shot anomaly detection (ZSAD) aims to detect anomalies and localize defective regions in unseen target domains without target training data. Recent ZSAD methods build on pretrained vision models, particularly CLIP, and construct normal and anomaly references from textual prompts or learnable visual representations. These methods perform anomaly discrimination primarily in spatial feature spaces, where subtle changes in texture, boundaries, and local structures can be confused with normal appearance variations. Although inconspicuous spatially, such defects can disrupt local texture regularity or boundary continuity, inducing response deviations across frequency bands. However, existing ZSAD methods do not explicitly model these frequency-dependent characteristics. Our image-domain analysis reveals that local defects exhibit spatial-frequency deviations from normal references across low-, middle-, and high-frequency bands, indicating that anomaly evidence is not universally dominated by high-frequency responses. Motivated by this observation, we propose FreqAnchorAD, a frequency-aware framework that organizes frequency-enhanced responses for anchor-relative anomaly discrimination. Specifically, the Local Frequency Compensation Module (LFCM) enhances intermediate patch tokens with local spatial-frequency cues. The Frequency-Deviation Anchor Projector (FDAP), our core discrimination module, organizes enhanced responses along a source-derived channel coordinate and measures anomaly evidence through relative similarity to normal and anomaly anchors. Finally, Asymmetric Anchor Supervision (AAS) stabilizes normal-anchor alignment while preserving diverse anomaly patterns. Experiments on thirteen industrial and medical benchmarks show that FreqAnchorAD achieves state-of-the-art mean performance in image-level anomaly recognition and pixel-level defect localization.
Abstract:Zero-shot 3D anomaly detection is essential for industrial quality inspection, where labeled anomaly samples are scarce. Meanwhile, existing methods lack an effective mechanism to fuse complementary 2D color images with 3D geometric structures, limiting their ability to detect both surface and structural defects in a unified framework. To address these issues, we propose CoGeoAD, a unified CLIP-based framework that fuses color and geometric features by constructing pixel-aligned paired multi-view images. The framework introduces a Data-Driven Multi-View Attention (MVA) mechanism to adaptively aggregate 3D features and a Multi-Stage Color-Geometric Fusion (MS-CGF) module to hierarchically integrate multi-level features from both modalities. Extensive experiments on the MVTec3D-AD and Eyecandies benchmarks demonstrate that CoGeoAD achieves state-of-the-art performance, effectively capturing both structural and textural anomalies in complex industrial scenarios. our source code is available at https://github.com/kingdomShu/CoGeoAD.
Abstract:Background: High-dimensional genomic data exhibit strong group correlation structures that challenge conventional feature selection methods, which often assume feature independence or rely on pre-defined pathways and are sensitive to outliers and model misspecification. Methods: We propose the Dorfman screening framework, a multi-stage procedure that forms data-driven variable groups via hierarchical clustering, performs group and within-group hypothesis testing, and refines selection using elastic net or adaptive elastic net. Robust variants incorporate OGK-based covariance estimation, rank-based correlation, and Huber-weighted regression to handle contaminated and non-normal data. Results: In simulations, Dorfman-Sparse-Adaptive-EN performed best under normal conditions, while Robust-OGK-Dorfman-Adaptive-EN showed clear advantages under data contamination, outperforming classical Dorfman and competing methods. Applied to NSCLC gene expression data for trametinib response, robust Dorfman methods achieved the lowest prediction errors and enriched recovery of clinically relevant genes. Conclusions: The Dorfman framework provides an efficient and robust approach to genomic feature selection. Robust-OGK-Dorfman-Adaptive-EN offers strong performance under both ideal and contaminated conditions and scales to ultra-high-dimensional settings, making it well suited for modern genomic biomarker discovery.
Abstract:Domain adaptation (DA) has been widely applied in the diabetic retinopathy (DR) grading of unannotated ultra-wide-field (UWF) fundus images, which can transfer annotated knowledge from labeled color fundus images. However, suffering from huge domain gaps and complex real-world scenarios, the DR grading performance of most mainstream DA is far from that of clinical diagnosis. To tackle this, we propose a novel source-free active domain adaptation (SFADA) in this paper. Specifically, we focus on DR grading problem itself and propose to generate features of color fundus images with continuously evolving relationships of DRs, actively select a few valuable UWF fundus images for labeling with local representation matching, and adapt model on UWF fundus images with DR lesion prototypes. Notably, the SFADA also takes data privacy and computational efficiency into consideration. Extensive experimental results demonstrate that our proposed SFADA achieves state-of-the-art DR grading performance, increasing accuracy by 20.9% and quadratic weighted kappa by 18.63% compared with baseline and reaching 85.36% and 92.38% respectively. These investigations show that the potential of our approach for real clinical practice is promising.




Abstract:The introduction of inexpensive 3D data acquisition devices has promisingly facilitated the wide availability and popularity of 3D point cloud, which attracts more attention on the effective extraction of novel 3D point cloud descriptors for accurate and efficient of 3D computer vision tasks. However, how to de- velop discriminative and robust feature descriptors from various point clouds remains a challenging task. This paper comprehensively investigates the exist- ing approaches for extracting 3D point cloud descriptors which are categorized into three major classes: local-based descriptor, global-based descriptor and hybrid-based descriptor. Furthermore, experiments are carried out to present a thorough evaluation of performance of several state-of-the-art 3D point cloud descriptors used widely in practice in terms of descriptiveness, robustness and efficiency.