GLACIER: A Multimodal Student-Teacher Foundation Model for Molecular Property Prediction

Deep learning models facilitate the discovery of molecules with tailored properties among billions of candidate compounds. However, the computational burden to develop and deploy state-of-the-art models continuously increases, limiting their scalability. Most large-scale models are unimodal in nature and overlook the potential to leverage complementary molecular data modalities. To address these shortcomings, this paper introduces the Graph-Language Alignment for Chemical Inference and Exploration using Representations (GLACIER) model, a student-teacher framework that integrates molecular graphs, SMILES strings, and physicochemical descriptors to learn rich molecular embeddings. Our framework consists of three stages: (1) we pretrain three student encoders on 100,000 drug-like molecules: a message-passing neural network for molecular graphs, a transformer-based encoder for SMILES strings, and a multilayer perceptron for physicochemical descriptors, (2) we fuse these student modalities using a novel Finsler geometry-aware module, and (3) distill complementary knowledge from large teacher models, including MiniMol and MolFormer, into a single lightweight model via contrastive learning. We demonstrate that GLACIER is a robust framework that delivers high predictive performance and computational efficiency in complex molecular property prediction tasks. Our code is publicly available at https://github.com/eemokey/glacier.

De-conflating Preference and Qualification: Constrained Dual-Perspective Reasoning for Job Recommendation with Large Language Models

Professional job recommendation involves a complex bipartite matching process that must reconcile a candidate's subjective preference with an employer's objective qualification. While Large Language Models (LLMs) are well-suited for modeling the rich semantics of resumes and job descriptions, existing paradigms often collapse these two decision dimensions into a single interaction signal, yielding confounded supervision under recruitment-funnel censoring and limiting policy controllability. To address these challenges, We propose JobRec, a generative job recommendation framework for de-conflating preference and qualification via constrained dual-perspective reasoning. JobRec introduces a Unified Semantic Alignment Schema that aligns candidate and job attributes into structured semantic layers, and a Two-Stage Cooperative Training Strategy that learns decoupled experts to separately infer preference and qualification. Building on these experts, a Lagrangian-based Policy Alignment module optimizes recommendations under explicit eligibility requirements, enabling controllable trade-offs. To mitigate data scarcity, we construct a synthetic dataset refined by experts. Experiments show that JobRec consistently outperforms strong baselines and provides improved controllability for strategy-aware professional matching.