Polynomial Graphical Lasso: Learning Edges from Gaussian Graph-Stationary Signals

This paper introduces Polynomial Graphical Lasso (PGL), a new approach to learning graph structures from nodal signals. Our key contribution lies in modeling the signals as Gaussian and stationary on the graph, enabling the development of a graph-learning formulation that combines the strengths of graphical lasso with a more encompassing model. Specifically, we assume that the precision matrix can take any polynomial form of the sought graph, allowing for increased flexibility in modeling nodal relationships. Given the resulting complexity and nonconvexity of the resulting optimization problem, we (i) propose a low-complexity algorithm that alternates between estimating the graph and precision matrices, and (ii) characterize its convergence. We evaluate the performance of PGL through comprehensive numerical simulations using both synthetic and real data, demonstrating its superiority over several alternatives. Overall, this approach presents a significant advancement in graph learning and holds promise for various applications in graph-aware signal analysis and beyond.

Mitigating Subpopulation Bias for Fair Network Topology Inference

We consider fair network topology inference from nodal observations. Real-world networks often exhibit biased connections based on sensitive nodal attributes. Hence, different subpopulations of nodes may not share or receive information equitably. We thus propose an optimization-based approach to accurately infer networks while discouraging biased edges. To this end, we present bias metrics that measure topological demographic parity to be applied as convex penalties, suitable for most optimization-based graph learning methods. Moreover, we encourage equitable treatment for any number of subpopulations of differing sizes. We validate our method on synthetic and real-world simulations using networks with both biased and unbiased connections.

Multimodal Interpretable Data-Driven Models for Early Prediction of Antimicrobial Multidrug Resistance Using Multivariate Time-Series

Electronic health records (EHR) is an inherently multimodal register of the patient's health status characterized by static data and multivariate time series (MTS). While MTS are a valuable tool for clinical prediction, their fusion with other data modalities can possibly result in more thorough insights and more accurate results. Deep neural networks (DNNs) have emerged as fundamental tools for identifying and defining underlying patterns in the healthcare domain. However, fundamental improvements in interpretability are needed for DNN models to be widely used in the clinical setting. In this study, we present an approach built on a collection of interpretable multimodal data-driven models that may anticipate and understand the emergence of antimicrobial multidrug resistance (AMR) germs in the intensive care unit (ICU) of the University Hospital of Fuenlabrada (Madrid, Spain). The profile and initial health status of the patient are modeled using static variables, while the evolution of the patient's health status during the ICU stay is modeled using several MTS, including mechanical ventilation and antibiotics intake. The multimodal DNNs models proposed in this paper include interpretable principles in addition to being effective at predicting AMR and providing an explainable prediction support system for AMR in the ICU. Furthermore, our proposed methodology based on multimodal models and interpretability schemes can be leveraged in additional clinical problems dealing with EHR data, broadening the impact and applicability of our results.

Learning graphs and simplicial complexes from data

Graphs are widely used to represent complex information and signal domains with irregular support. Typically, the underlying graph topology is unknown and must be estimated from the available data. Common approaches assume pairwise node interactions and infer the graph topology based on this premise. In contrast, our novel method not only unveils the graph topology but also identifies three-node interactions, referred to in the literature as second-order simplicial complexes (SCs). We model signals using a graph autoregressive Volterra framework, enhancing it with structured graph Volterra kernels to learn SCs. We propose a mathematical formulation for graph and SC inference, solving it through convex optimization involving group norms and mask matrices. Experimental results on synthetic and real-world data showcase a superior performance for our approach compared to existing methods.

Robust Graph Neural Network based on Graph Denoising

Graph Neural Networks (GNNs) have emerged as a notorious alternative to address learning problems dealing with non-Euclidean datasets. However, although most works assume that the graph is perfectly known, the observed topology is prone to errors stemming from observational noise, graph-learning limitations, or adversarial attacks. If ignored, these perturbations may drastically hinder the performance of GNNs. To address this limitation, this work proposes a robust implementation of GNNs that explicitly accounts for the presence of perturbations in the observed topology. For any task involving GNNs, our core idea is to i) solve an optimization problem not only over the learnable parameters of the GNN but also over the true graph, and ii) augment the fitting cost with a term accounting for discrepancies on the graph. Specifically, we consider a convolutional GNN based on graph filters and follow an alternating optimization approach to handle the (non-differentiable and constrained) optimization problem by combining gradient descent and projected proximal updates. The resulting algorithm is not limited to a particular type of graph and is amenable to incorporating prior information about the perturbations. Finally, we assess the performance of the proposed method through several numerical experiments.

Recovering Missing Node Features with Local Structure-based Embeddings

Node features bolster graph-based learning when exploited jointly with network structure. However, a lack of nodal attributes is prevalent in graph data. We present a framework to recover completely missing node features for a set of graphs, where we only know the signals of a subset of graphs. Our approach incorporates prior information from both graph topology and existing nodal values. We demonstrate an example implementation of our framework where we assume that node features depend on local graph structure. Missing nodal values are estimated by aggregating known features from the most similar nodes. Similarity is measured through a node embedding space that preserves local topological features, which we train using a Graph AutoEncoder. We empirically show not only the accuracy of our feature estimation approach but also its value for downstream graph classification. Our success embarks on and implies the need to emphasize the relationship between node features and graph structure in graph-based learning.

Blind Deconvolution of Sparse Graph Signals in the Presence of Perturbations

Blind deconvolution over graphs involves using (observed) output graph signals to obtain both the inputs (sources) as well as the filter that drives (models) the graph diffusion process. This is an ill-posed problem that requires additional assumptions, such as the sources being sparse, to be solvable. This paper addresses the blind deconvolution problem in the presence of imperfect graph information, where the observed graph is a perturbed version of the (unknown) true graph. While not having perfect knowledge of the graph is arguably more the norm than the exception, the body of literature on this topic is relatively small. This is partly due to the fact that translating the uncertainty about the graph topology to standard graph signal processing tools (e.g. eigenvectors or polynomials of the graph) is a challenging endeavor. To address this limitation, we propose an optimization-based estimator that solves the blind identification in the vertex domain, aims at estimating the inverse of the generating filter, and accounts explicitly for additive graph perturbations. Preliminary numerical experiments showcase the effectiveness and potential of the proposed algorithm.

Joint Network Topology Inference in the Presence of Hidden Nodes

We investigate the increasingly prominent task of jointly inferring multiple networks from nodal observations. While most joint inference methods assume that observations are available at all nodes, we consider the realistic and more difficult scenario where a subset of nodes are hidden and cannot be measured. Under the assumptions that the partially observed nodal signals are graph stationary and the networks have similar connectivity patterns, we derive structural characteristics of the connectivity between hidden and observed nodes. This allows us to formulate an optimization problem for estimating networks while accounting for the influence of hidden nodes. We identify conditions under which a convex relaxation yields the sparsest solution, and we formalize the performance of our proposed optimization problem with respect to the effect of the hidden nodes. Finally, synthetic and real-world simulations provide evaluations of our method in comparison with other baselines.

Graph Signal Processing: History, Development, Impact, and Outlook

Graph signal processing (GSP) generalizes signal processing (SP) tasks to signals living on non-Euclidean domains whose structure can be captured by a weighted graph. Graphs are versatile, able to model irregular interactions, easy to interpret, and endowed with a corpus of mathematical results, rendering them natural candidates to serve as the basis for a theory of processing signals in more irregular domains. In this article, we provide an overview of the evolution of GSP, from its origins to the challenges ahead. The first half is devoted to reviewing the history of GSP and explaining how it gave rise to an encompassing framework that shares multiple similarities with SP. A key message is that GSP has been critical to develop novel and technically sound tools, theory, and algorithms that, by leveraging analogies with and the insights of digital SP, provide new ways to analyze, process, and learn from graph signals. In the second half, we shift focus to review the impact of GSP on other disciplines. First, we look at the use of GSP in data science problems, including graph learning and graph-based deep learning. Second, we discuss the impact of GSP on applications, including neuroscience and image and video processing. We conclude with a brief discussion of the emerging and future directions of GSP.

Graph Learning from Gaussian and Stationary Graph Signals

Graphs have become pervasive tools to represent information and datasets with irregular support. However, in many cases, the underlying graph is either unavailable or naively obtained, calling for more advanced methods to its estimation. Indeed, graph topology inference methods that estimate the network structure from a set of signal observations have a long and well established history. By assuming that the observations are both Gaussian and stationary in the sought graph, this paper proposes a new scheme to learn the network from nodal observations. Consideration of graph stationarity overcomes some of the limitations of the classical Graphical Lasso algorithm, which is constrained to a more specific class of graphical models. On the other hand, Gaussianity allows us to regularize the estimation, requiring less samples than in existing graph stationarity-based approaches. While the resultant estimation (optimization) problem is more complex and non-convex, we design an alternating convex approach able to find a stationary solution. Numerical tests with synthetic and real data are presented, and the performance of our approach is compared with existing alternatives.