AutoSAM: an Agentic Framework for Automating Input File Generation for the SAM Code with Multi-Modal Retrieval-Augmented Generation

In the design and safety analysis of advanced reactor systems, constructing input files for system-level thermal-hydraulics codes such as the System Analysis Module (SAM) remains a labor-intensive task. Analysts must extract and reconcile design data from heterogeneous engineering documents and manually translate it into solver-specific syntax. In this paper, we present AutoSAM, an agentic framework that automates SAM input file generation. The framework combines a large language model agent with retrieval-augmented generation over the solver's user guide and theory manual, together with specialized tools for analyzing PDFs, images, spreadsheets, and text files. AutoSAM ingests unstructured engineering documents, including system diagrams, design reports, and data tables, extracts simulation-relevant parameters into a human-auditable intermediate representation, and synthesizes validated, solver-compatible input decks. Its multimodal retrieval pipeline integrates scientific text extraction, vision-based figure interpretation, semantic embedding, and query answering. We evaluate AutoSAM on four case studies of increasing complexity: a single-pipe steady-state model, a solid-fuel channel with temperature reactivity feedback, the Advanced Burner Test Reactor core, and the Molten Salt Reactor Experiment primary loop. Across all cases, the agent produces runnable SAM models consistent with expected thermal-hydraulic behavior while explicitly identifying missing data and labeling assumed values. The framework achieves 100% utilization of structured inputs, about 88% extraction from PDF text, and 100% completeness in vision-based geometric extraction. These results demonstrate a practical path toward prompt-driven reactor modeling, in which analysts provide system descriptions and supporting documentation while the agent translates them into transparent, and executable, SAM simulations.

CoCR-RAG: Enhancing Retrieval-Augmented Generation in Web Q&A via Concept-oriented Context Reconstruction

Retrieval-augmented generation (RAG) has shown promising results in enhancing Q&A by incorporating information from the web and other external sources. However, the supporting documents retrieved from the heterogeneous web often originate from multiple sources with diverse writing styles, varying formats, and inconsistent granularity. Fusing such multi-source documents into a coherent and knowledge-intensive context remains a significant challenge, as the presence of irrelevant and redundant information can compromise the factual consistency of the inferred answers. This paper proposes the Concept-oriented Context Reconstruction RAG (CoCR-RAG), a framework that addresses the multi-source information fusion problem in RAG through linguistically grounded concept-level integration. Specifically, we introduce a concept distillation algorithm that extracts essential concepts from Abstract Meaning Representation (AMR), a stable semantic representation that structures the meaning of texts as logical graphs. The distilled concepts from multiple retrieved documents are then fused and reconstructed into a unified, information-intensive context by Large Language Models, which supplement only the necessary sentence elements to highlight the core knowledge. Experiments on the PopQA and EntityQuestions datasets demonstrate that CoCR-RAG significantly outperforms existing context-reconstruction methods across these Web Q&A benchmarks. Furthermore, CoCR-RAG shows robustness across various backbone LLMs, establishing itself as a flexible, plug-and-play component adaptable to different RAG frameworks.

Context Selection for Hypothesis and Statistical Evidence Extraction from Full-Text Scientific Articles

Extracting hypotheses and their supporting statistical evidence from full-text scientific articles is central to the synthesis of empirical findings, but remains difficult due to document length and the distribution of scientific arguments across sections of the paper. The work studies a sequential full-text extraction setting, where the statement of a primary finding in an article's abstract is linked to (i) a corresponding hypothesis statement in the paper body and (ii) the statistical evidence that supports or refutes that hypothesis. This formulation induces a challenging within-document retrieval setting in which many candidate paragraphs are topically related to the finding but differ in rhetorical role, creating hard negatives for retrieval and extraction. Using a two-stage retrieve-and-extract framework, we conduct a controlled study of retrieval design choices, varying context quantity, context quality (standard Retrieval Augmented Generation, reranking, and a fine-tuned retriever paired with reranking), as well as an oracle paragraph setting to separate retrieval failures from extraction limits across four Large Language Model extractors. We find that targeted context selection consistently improves hypothesis extraction relative to full-text prompting, with gains concentrated in configurations that optimize retrieval quality and context cleanliness. In contrast, statistical evidence extraction remains substantially harder. Even with oracle paragraphs, performance remains moderate, indicating persistent extractor limitations in handling hybrid numeric-textual statements rather than retrieval failures alone.

TopoChunker: Topology-Aware Agentic Document Chunking Framework

Current document chunking methods for Retrieval-Augmented Generation (RAG) typically linearize text. This forced linearization strips away intrinsic topological hierarchies, creating ``semantic fragmentation'' that degrades downstream retrieval quality. In this paper, we propose TopoChunker, an agentic framework that maps heterogeneous documents onto a Structured Intermediate Representation (SIR) to explicitly preserve cross-segment dependencies. To balance structural fidelity with computational cost, TopoChunker employs a dual-agent architecture. An Inspector Agent dynamically routes documents through cost-optimized extraction paths, while a Refiner Agent performs capacity auditing and topological context disambiguation to reconstruct hierarchical lineage. Evaluated on unstructured narratives (GutenQA) and complex reports (GovReport), TopoChunker demonstrates state-of-the-art performance. It outperforms the strongest LLM-based baseline by 8.0% in absolute generation accuracy and achieves an 83.26% Recall@3, while simultaneously reducing token overhead by 23.5%, offering a scalable approach for structure-aware RAG.

VAREX: A Benchmark for Multi-Modal Structured Extraction from Documents

We introduce VAREX (VARied-schema EXtraction), a benchmark for evaluating multimodal foundation models on structured data extraction from government forms. VAREX employs a Reverse Annotation pipeline that programmatically fills PDF templates with synthetic values, producing deterministic ground truth validated through three-phase quality assurance. The benchmark comprises 1,777 documents with 1,771 unique schemas across three structural categories, each provided in four input modalities: plain text, layout-preserving text (whitespace-aligned to approximate column positions), document image, or both text and image combined. Unlike existing benchmarks that evaluate from a single input representation, VAREX provides four controlled modalities per document, enabling systematic ablation of how input format affects extraction accuracy -- a capability absent from prior benchmarks. We evaluate 20 models from frontier proprietary models to small open models, with particular attention to models <=4B parameters suitable for cost-sensitive and latency-constrained deployment. Results reveal that (1) below 4B parameters, structured output compliance -- not extraction capability -- is a dominant bottleneck; in particular, schema echo (models producing schema-conforming structure instead of extracted values) depresses scores by 45-65 pp (percentage points) in affected models; (2) extraction-specific fine-tuning at 2B yields +81 pp gains, demonstrating that the instruction-following deficit is addressable without scale; (3) layout-preserving text provides the largest accuracy gain (+3-18 pp), exceeding pixel-level visual cues; and (4) the benchmark most effectively discriminates models in the 60-95% accuracy band. Dataset and evaluation code are publicly available.

Selective Fine-Tuning of GPT Architectures for Parameter-Efficient Clinical Text Classification

The rapid expansion of electronic health record (EHR) systems has generated large volumes of unstructured clinical narratives that contain valuable information for disease identification, patient cohort discovery, and clinical decision support. Extracting structured knowledge from these free-text documents remains challenging because clinical language is highly specialized, labeled datasets are limited, and full fine-tuning of large pretrained language models can require substantial computational resources. Efficient adaptation strategies are therefore essential for practical clinical natural language processing applications. This study proposes a parameter-efficient selective fine-tuning framework for adapting GPT-2 to clinical text classification tasks. Instead of updating the entire pretrained model, the majority of network parameters are frozen, and only the final Transformer block, the final layer normalization module, and a lightweight classification head are updated during training. This design substantially reduces the number of trainable parameters while preserving the contextual representation capabilities learned during pretraining. The proposed approach is evaluated using radiology reports from the MIMIC-IV-Note dataset with automatically derived CheXpert-style labels. Experiments on 50,000 radiology reports demonstrate that selective fine-tuning achieves approximately 91% classification accuracy while updating fewer than 6% of the model parameters. Comparative experiments with head-only training and full-model fine-tuning show that the proposed method provides a favorable balance between predictive performance and computational efficiency. These results indicate that selective fine-tuning offers an efficient and scalable framework for clinical text classification.

TheraAgent: Multi-Agent Framework with Self-Evolving Memory and Evidence-Calibrated Reasoning for PET Theranostics

PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond, demanding reliable pre-therapy prediction. While LLM-based agents have shown remarkable potential in complex medical diagnosis, their application to PET theranostic outcome prediction remains unexplored, which faces three key challenges: (1) data and knowledge scarcity: RLT was only FDA-approved in 2022, yielding few training cases and insufficient domain knowledge in general LLMs; (2) heterogeneous information integration: robust prediction hinges on structured knowledge extraction from PET/CT, laboratory tests, and free-text clinical documentation; (3) evidence-grounded reasoning: clinical decisions must be anchored in trial evidence rather than LLM hallucinations. In this paper, we present TheraAgent, to our knowledge, the first agentic framework for PET theranostics, with three core innovations: (1) Multi-Expert Feature Extraction with Confidence-Weighted Consensus, where three specialized experts process heterogeneous inputs with uncertainty quantification; (2) Self-Evolving Agentic Memory (SEA-Mem), which learns prognostic patterns from accumulated cases, enabling case-based reasoning from limited data; (3) Evidence-Calibrated Reasoning, integrating a curated theranostics knowledge base to ground predictions in VISION/TheraP trial evidence. Evaluated on 35 real patients and 400 synthetic cases, TheraAgent achieves 75.7% overall accuracy on real patients and 87.0% on synthetic cases, outperforming MDAgents and MedAgent-Pro by over 20%. These results highlight a promising blueprint for trustworthy AI agents in PET theranostics, enabling trial-calibrated, multi-source decision support. Code will be released upon acceptance.

GLM-OCR Technical Report

GLM-OCR is an efficient 0.9B-parameter compact multimodal model designed for real-world document understanding. It combines a 0.4B-parameter CogViT visual encoder with a 0.5B-parameter GLM language decoder, achieving a strong balance between computational efficiency and recognition performance. To address the inefficiency of standard autoregressive decoding in deterministic OCR tasks, GLM-OCR introduces a Multi-Token Prediction (MTP) mechanism that predicts multiple tokens per step, significantly improving decoding throughput while keeping memory overhead low through shared parameters. At the system level, a two-stage pipeline is adopted: PP-DocLayout-V3 first performs layout analysis, followed by parallel region-level recognition. Extensive evaluations on public benchmarks and industrial scenarios show that GLM-OCR achieves competitive or state-of-the-art performance in document parsing, text and formula transcription, table structure recovery, and key information extraction. Its compact architecture and structured generation make it suitable for both resource-constrained edge deployment and large-scale production systems.

DocSage: An Information Structuring Agent for Multi-Doc Multi-Entity Question Answering

Multi-document Multi-entity Question Answering inherently demands models to track implicit logic between multiple entities across scattered documents. However, existing Large Language Models (LLMs) and Retrieval-Augmented Generation (RAG) frameworks suffer from critical limitations: standard RAG's vector similarity-based coarse-grained retrieval often omits critical facts, graph-based RAG fails to efficiently integrate fragmented complex relationship networks, and both lack schema awareness, leading to inadequate cross-document evidence chain construction and inaccurate entity relationship deduction. To address these challenges, we propose DocSage, an end-to-end agentic framework that integrates dynamic schema discovery, structured information extraction, and schema-aware relational reasoning with error guarantees. DocSage operates through three core modules: (1) A schema discovery module dynamically infers query-specific minimal joinable schemas to capture essential entities and relationships; (2) An extraction module transforms unstructured text into semantically coherent relational tables, enhanced by error-aware correction mechanisms to reduce extraction errors; (3) A reasoning module performs multi-hop relational reasoning over structured tables, leveraging schema awareness to efficiently align cross-document entities and aggregate evidence. This agentic design offers three key advantages: precise fact localization via SQL-powered indexing, natural support for cross-document entity joins through relational tables, and mitigated LLM attention diffusion via structured representation. Evaluations on two MDMEQA benchmarks demonstrate that DocSage significantly outperforms state-of-the-art long-context LLMs and RAG systems, achieving more than 27% accuracy improvements respectively.

MITRA: An AI Assistant for Knowledge Retrieval in Physics Collaborations

Large-scale scientific collaborations, such as the Compact Muon Solenoid (CMS) at CERN, produce a vast and ever-growing corpus of internal documentation. Navigating this complex information landscape presents a significant challenge for both new and experienced researchers, hindering knowledge sharing and slowing down the pace of scientific discovery. To address this, we present a prototype of MITRA, a Retrieval-Augmented Generation (RAG) based system, designed to answer specific, context-aware questions about physics analyses. MITRA employs a novel, automated pipeline using Selenium for document retrieval from internal databases and Optical Character Recognition (OCR) with layout parsing for high-fidelity text extraction. Crucially, MITRA's entire framework, from the embedding model to the Large Language Model (LLM), is hosted on-premise, ensuring that sensitive collaboration data remains private. We introduce a two-tiered vector database architecture that first identifies the relevant analysis from abstracts before focusing on the full documentation, resolving potential ambiguities between different analyses. We demonstrate the prototype's superior retrieval performance against a standard keyword-based baseline on realistic queries and discuss future work towards developing a comprehensive research agent for large experimental collaborations.