Abstract:Identifying a meaningful quantum speedup requires more than matching a classical problem to a familiar quantum primitive: the claim must preserve the task, respect access and output models, expose required promises, and remain within a defensible complexity scope. We present QuantumMind, an auditable agentic workflow for generating and conservatively screening quantum-acceleration hypotheses. A fixed sequence of typed, role-specialized actions formalizes the public task, analyzes structure and classical bottlenecks, matches a source-linked registry of quantum primitives and barriers, and constructs a scoped candidate scheme. A deterministic ten-check validator assigns the authoritative verdict; completed states are compiled into a Quantum Acceleration Evidence Graph and passed through a downward-only research screen that cannot strengthen the decision. We evaluate QuantumMind against seven task-adapted prompting and agentic controls on 582 identical open-discovery tasks. Under the frozen Open-Discovery Score (ODS), QuantumMind obtains 53.1 mean ODS, exceeding the strongest baseline by 17.3 points (48.2% relative), and wins 355 of 582 paired tasks against that baseline. It passes the graph audit on 99.8% of tasks, compared with 43.6% for the strongest baseline, and ranks first in all seven task families. The results indicate that typed state transitions and deterministic evidence control contribute beyond fluent generation alone.
Abstract:Multimodal medical anomaly detection identifies samples deviating from normal patterns, where scarce abnormal cases make normality modeling from normal data practical. In retinal Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) anomaly detection, existing unsupervised methods rely on visual feature distributions, reconstruction residuals, or encoder-decoder discrepancies, making anomaly scores depend on appearance-level deviations, while multimodal normality also contains semantic organization described in normal medical reports. To this end, we propose Report-Guided Mixture-of-Experts (ReMoE), which distills normal report semantics into an image-to-text prior student, builds modality-aware priors, and uses Report-Guided Modality Modulation (RMM) to modulate features through mixture-of-experts routing. Experiments on a private OCT/OCTA dataset with paired normal reports and a public OCTA500-3MM setting using a fixed normal report demonstrate state-of-the-art performance.
Abstract:Medical image anomaly detection remains challenging because networks pretrained on natural images often exhibit limited adaptability to medical images, where abnormal patterns appear as fine-grained local shifts, multi-scale contextual mismatches, and orientation-sensitive structural deviations. To address this, we propose the Collaborative Feature Refinement Network (CFR-Net), which combines shared teacher-student feature refinement before decoding with cross-space consistency after decoding. CFR-Net refines frozen teacher features and trainable student features using a Multi-Path Feature Refinement Module (MPFRM) with shared parameters, imposing common multi-path refinement rules on generic visual references and representations adapted to the medical domain, thereby mitigating domain discrepancy while modeling local, multi-scale, and orientation-sensitive feature characteristics. A variance-sensitive objective and dynamic ``homework set'' reorganization further support layer-adaptive consistency learning. Experiments on medical benchmarks show that CFR-Net achieves competitive anomaly classification and strong anomaly localization performance when trained on normal data.