PRETI: Patient-Aware Retinal Foundation Model via Metadata-Guided Representation Learning

Retinal foundation models have significantly advanced retinal image analysis by leveraging self-supervised learning to reduce dependence on labeled data while achieving strong generalization. Many recent approaches enhance retinal image understanding using report supervision, but obtaining clinical reports is often costly and challenging. In contrast, metadata (e.g., age, gender) is widely available and serves as a valuable resource for analyzing disease progression. To effectively incorporate patient-specific information, we propose PRETI, a retinal foundation model that integrates metadata-aware learning with robust self-supervised representation learning. We introduce Learnable Metadata Embedding (LME), which dynamically refines metadata representations. Additionally, we construct patient-level data pairs, associating images from the same individual to improve robustness against non-clinical variations. To further optimize retinal image representation, we propose Retina-Aware Adaptive Masking (RAAM), a strategy that selectively applies masking within the retinal region and dynamically adjusts the masking ratio during training. PRETI captures both global structures and fine-grained pathological details, resulting in superior diagnostic performance. Extensive experiments demonstrate that PRETI achieves state-of-the-art results across diverse diseases and biomarker predictions using in-house and public data, indicating the importance of metadata-guided foundation models in retinal disease analysis. Our code and pretrained model are available at https://github.com/MICV-yonsei/PRETI

Spatial Transport Optimization by Repositioning Attention Map for Training-Free Text-to-Image Synthesis

Diffusion-based text-to-image (T2I) models have recently excelled in high-quality image generation, particularly in a training-free manner, enabling cost-effective adaptability and generalization across diverse tasks. However, while the existing methods have been continuously focusing on several challenges, such as "missing objects" and "mismatched attributes," another critical issue of "mislocated objects" remains where generated spatial positions fail to align with text prompts. Surprisingly, ensuring such seemingly basic functionality remains challenging in popular T2I models due to the inherent difficulty of imposing explicit spatial guidance via text forms. To address this, we propose STORM (Spatial Transport Optimization by Repositioning Attention Map), a novel training-free approach for spatially coherent T2I synthesis. STORM employs Spatial Transport Optimization (STO), rooted in optimal transport theory, to dynamically adjust object attention maps for precise spatial adherence, supported by a Spatial Transport (ST) Cost function that enhances spatial understanding. Our analysis shows that integrating spatial awareness is most effective in the early denoising stages, while later phases refine details. Extensive experiments demonstrate that STORM surpasses existing methods, effectively mitigating mislocated objects while improving missing and mismatched attributes, setting a new benchmark for spatial alignment in T2I synthesis.