"Can We Detect Substance Use Disorder?": Knowledge and Time Aware Classification on Social Media from Darkweb

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the "opioid crisis". The relationship between substance use and mental health has been extensively studied, with one possible relationship being: substance misuse causes poor mental health. However, the lack of evidence on the relationship has resulted in opioids being largely inaccessible through legal means. This study analyzes the substance use posts on social media with opioids being sold through crypto market listings. We use the Drug Abuse Ontology, state-of-the-art deep learning, and knowledge-aware BERT-based models to generate sentiment and emotion for the social media posts to understand users' perceptions on social media by investigating questions such as: which synthetic opioids people are optimistic, neutral, or negative about? or what kind of drugs induced fear and sorrow? or what kind of drugs people love or are thankful about? or which drugs people think negatively about? or which opioids cause little to no sentimental reaction. We discuss how we crawled crypto market data and its use in extracting posts for fentanyl, fentanyl analogs, and other novel synthetic opioids. We also perform topic analysis associated with the generated sentiments and emotions to understand which topics correlate with people's responses to various drugs. Additionally, we analyze time-aware neural models built on these features while considering historical sentiment and emotional activity of posts related to a drug. The most effective model performs well (statistically significant) with (macroF1=82.12, recall =83.58) to identify substance use disorder.

A Computational Approach to Understand Mental Health from Reddit: Knowledge-aware Multitask Learning Framework

Analyzing gender is critical to study mental health (MH) support in CVD (cardiovascular disease). The existing studies on using social media for extracting MH symptoms consider symptom detection and tend to ignore user context, disease, or gender. The current study aims to design and evaluate a system to capture how MH symptoms associated with CVD are expressed differently with the gender on social media. We observe that the reliable detection of MH symptoms expressed by persons with heart disease in user posts is challenging because of the co-existence of (dis)similar MH symptoms in one post and due to variation in the description of symptoms based on gender. We collect a corpus of $150k$ items (posts and comments) annotated using the subreddit labels and transfer learning approaches. We propose GeM, a novel task-adaptive multi-task learning approach to identify the MH symptoms in CVD patients based on gender. Specifically, we adapt a knowledge-assisted RoBERTa based bi-encoder model to capture CVD-related MH symptoms. Moreover, it enhances the reliability for differentiating the gender language in MH symptoms when compared to the state-of-art language models. Our model achieves high (statistically significant) performance and predicts four labels of MH issues and two gender labels, which outperforms RoBERTa, improving the recall by 2.14% on the symptom identification task and by 2.55% on the gender identification task.

eDarkTrends: Harnessing Social Media Trends in Substance use disorders for Opioid Listings on Cryptomarket

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being substance misuse causes poor mental health. However, the lack of evidence on the relationship has resulted in opioids being largely inaccessible through legal means. This study analyzes the substance misuse posts on social media with the opioids being sold through crypto market listings. We use the Drug Abuse Ontology, state-of-the-art deep learning, and BERT-based models to generate sentiment and emotion for the social media posts to understand user perception on social media by investigating questions such as, which synthetic opioids people are optimistic, neutral, or negative about or what kind of drugs induced fear and sorrow or what kind of drugs people love or thankful about or which drug people think negatively about or which opioids cause little to no sentimental reaction. We also perform topic analysis associated with the generated sentiments and emotions to understand which topics correlate with people's responses to various drugs. Our findings can help shape policy to help isolate opioid use cases where timely intervention may be required to prevent adverse consequences, prevent overdose-related deaths, and worsen the epidemic.

"Is depression related to cannabis?": A knowledge-infused model for Entity and Relation Extraction with Limited Supervision

With strong marketing advocacy of the benefits of cannabis use for improved mental health, cannabis legalization is a priority among legislators. However, preliminary scientific research does not conclusively associate cannabis with improved mental health. In this study, we explore the relationship between depression and consumption of cannabis in a targeted social media corpus involving personal use of cannabis with the intent to derive its potential mental health benefit. We use tweets that contain an association among three categories annotated by domain experts - Reason, Effect, and Addiction. The state-of-the-art Natural Langauge Processing techniques fall short in extracting these relationships between cannabis phrases and the depression indicators. We seek to address the limitation by using domain knowledge; specifically, the Drug Abuse Ontology for addiction augmented with Diagnostic and Statistical Manual of Mental Disorders lexicons for mental health. Because of the lack of annotations due to the limited availability of the domain experts' time, we use supervised contrastive learning in conjunction with GPT-3 trained on a vast corpus to achieve improved performance even with limited supervision. Experimental results show that our method can significantly extract cannabis-depression relationships better than the state-of-the-art relation extractor. High-quality annotations can be provided using a nearest neighbor approach using the learned representations that can be used by the scientific community to understand the association between cannabis and depression better.

"When they say weed causes depression, but it's your fav antidepressant": Knowledge-aware Attention Framework for Relationship Extraction

With the increasing legalization of medical and recreational use of cannabis, more research is needed to understand the association between depression and consumer behavior related to cannabis consumption. Big social media data has potential to provide deeper insights about these associations to public health analysts. In this interdisciplinary study, we demonstrate the value of incorporating domain-specific knowledge in the learning process to identify the relationships between cannabis use and depression. We develop an end-to-end knowledge infused deep learning framework (Gated-K-BERT) that leverages the pre-trained BERT language representation model and domain-specific declarative knowledge source (Drug Abuse Ontology (DAO)) to jointly extract entities and their relationship using gated fusion sharing mechanism. Our model is further tailored to provide more focus to the entities mention in the sentence through entity-position aware attention layer, where ontology is used to locate the target entities position. Experimental results show that inclusion of the knowledge-aware attentive representation in association with BERT can extract the cannabis-depression relationship with better coverage in comparison to the state-of-the-art relation extractor.