MoMA: A Mixture-of-Multimodal-Agents Architecture for Enhancing Clinical Prediction Modelling

Multimodal electronic health record (EHR) data provide richer, complementary insights into patient health compared to single-modality data. However, effectively integrating diverse data modalities for clinical prediction modeling remains challenging due to the substantial data requirements. We introduce a novel architecture, Mixture-of-Multimodal-Agents (MoMA), designed to leverage multiple large language model (LLM) agents for clinical prediction tasks using multimodal EHR data. MoMA employs specialized LLM agents ("specialist agents") to convert non-textual modalities, such as medical images and laboratory results, into structured textual summaries. These summaries, together with clinical notes, are combined by another LLM ("aggregator agent") to generate a unified multimodal summary, which is then used by a third LLM ("predictor agent") to produce clinical predictions. Evaluating MoMA on three prediction tasks using real-world datasets with different modality combinations and prediction settings, MoMA outperforms current state-of-the-art methods, highlighting its enhanced accuracy and flexibility across various tasks.

Evaluating Language Model Character Traits

Language models (LMs) can exhibit human-like behaviour, but it is unclear how to describe this behaviour without undue anthropomorphism. We formalise a behaviourist view of LM character traits: qualities such as truthfulness, sycophancy, or coherent beliefs and intentions, which may manifest as consistent patterns of behaviour. Our theory is grounded in empirical demonstrations of LMs exhibiting different character traits, such as accurate and logically coherent beliefs, and helpful and harmless intentions. We find that the consistency with which LMs exhibit certain character traits varies with model size, fine-tuning, and prompting. In addition to characterising LM character traits, we evaluate how these traits develop over the course of an interaction. We find that traits such as truthfulness and harmfulness can be stationary, i.e., consistent over an interaction, in certain contexts, but may be reflective in different contexts, meaning they mirror the LM's behavior in the preceding interaction. Our formalism enables us to describe LM behaviour precisely in intuitive language, without undue anthropomorphism.