MAFM^3: Modular Adaptation of Foundation Models for Multi-Modal Medical AI

Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Instead of building separate models, we propose MAFM^3 (Modular Adaptation of Foundation Models for Multi-Modal Medical AI), a framework that enables a single foundation model to expand into diverse domains, tasks, and modalities through lightweight modular components. These components serve as specialized skill sets that allow the system to flexibly activate the appropriate capability at the inference time, depending on the input type or clinical objective. Unlike conventional adaptation methods that treat each new task or modality in isolation, MAFM^3 provides a unified and expandable framework for efficient multitask and multimodality adaptation. Empirically, we validate our approach by adapting a chest CT foundation model initially trained for classification into prognosis and segmentation modules. Our results show improved performance on both tasks. Furthermore, by incorporating PET scans, MAFM^3 achieved an improvement in the Dice score 5% compared to the respective baselines. These findings establish that foundation models, when equipped with modular components, are not inherently constrained to their initial training scope but can evolve into multitask, multimodality systems for medical imaging. The code implementation of this work can be found at https://github.com/Areeb2735/CTscan_prognosis_VLM

Emergence of Primacy and Recency Effect in Mamba: A Mechanistic Point of View

We study memory in state-space language models using primacy and recency effects as behavioral tools to uncover how information is retained and forgotten over time. Applying structured recall tasks to the Mamba architecture, we observe a consistent U-shaped accuracy profile, indicating strong performance at the beginning and end of input sequences. We identify three mechanisms that give rise to this pattern. First, long-term memory is supported by a sparse subset of channels within the model's selective state space block, which persistently encode early input tokens and are causally linked to primacy effects. Second, short-term memory is governed by delta-modulated recurrence: recent inputs receive more weight due to exponential decay, but this recency advantage collapses when distractor items are introduced, revealing a clear limit to memory depth. Third, we find that memory allocation is dynamically modulated by semantic regularity: repeated relations in the input sequence shift the delta gating behavior, increasing the tendency to forget intermediate items. We validate these findings via targeted ablations and input perturbations on two large-scale Mamba-based language models: one with 1.4B and another with 7B parameters.