Weakly Supervised Multi-Task Representation Learning for Human Activity Analysis Using Wearables

Sensor data streams from wearable devices and smart environments are widely studied in areas like human activity recognition (HAR), person identification, or health monitoring. However, most of the previous works in activity and sensor stream analysis have been focusing on one aspect of the data, e.g. only recognizing the type of the activity or only identifying the person who performed the activity. We instead propose an approach that uses a weakly supervised multi-output siamese network that learns to map the data into multiple representation spaces, where each representation space focuses on one aspect of the data. The representation vectors of the data samples are positioned in the space such that the data with the same semantic meaning in that aspect are closely located to each other. Therefore, as demonstrated with a set of experiments, the trained model can provide metrics for clustering data based on multiple aspects, allowing it to address multiple tasks simultaneously and even to outperform single task supervised methods in many situations. In addition, further experiments are presented that in more detail analyze the effect of the architecture and of using multiple tasks within this framework, that investigate the scalability of the model to include additional tasks, and that demonstrate the ability of the framework to combine data for which only partial relationship information with respect to the target tasks is available.

Unsupervised Embedding Learning for Human Activity Recognition Using Wearable Sensor Data

The embedded sensors in widely used smartphones and other wearable devices make the data of human activities more accessible. However, recognizing different human activities from the wearable sensor data remains a challenging research problem in ubiquitous computing. One of the reasons is that the majority of the acquired data has no labels. In this paper, we present an unsupervised approach, which is based on the nature of human activity, to project the human activities into an embedding space in which similar activities will be located closely together. Using this, subsequent clustering algorithms can benefit from the embeddings, forming behavior clusters that represent the distinct activities performed by a person. Results of experiments on three labeled benchmark datasets demonstrate the effectiveness of the framework and show that our approach can help the clustering algorithm achieve improved performance in identifying and categorizing the underlying human activities compared to unsupervised techniques applied directly to the original data set.

Siamese Networks for Weakly Supervised Human Activity Recognition

Deep learning has been successfully applied to human activity recognition. However, training deep neural networks requires explicitly labeled data which is difficult to acquire. In this paper, we present a model with multiple siamese networks that are trained by using only the information about the similarity between pairs of data samples without knowing the explicit labels. The trained model maps the activity data samples into fixed size representation vectors such that the distance between the vectors in the representation space approximates the similarity of the data samples in the input space. Thus, the trained model can work as a metric for a wide range of different clustering algorithms. The training process minimizes a similarity loss function that forces the distance metric to be small for pairs of samples from the same kind of activity, and large for pairs of samples from different kinds of activities. We evaluate the model on three datasets to verify its effectiveness in segmentation and recognition of continuous human activity sequences.

Histopathology Slide Indexing and Search: Are We There Yet?

The search and retrieval of digital histopathology slides is an important task that has yet to be solved. In this case study, we investigate the clinical readiness of three state-of-the-art histopathology slide search engines, Yottixel, SISH, and RetCCL, on three patients with solid tumors. We provide a qualitative assessment of each model's performance in providing retrieval results that are reliable and useful to pathologists. We found that all three image search engines fail to produce consistently reliable results and have difficulties in capturing granular and subtle features of malignancy, limiting their diagnostic accuracy. Based on our findings, we also propose a minimal set of requirements to further advance the development of accurate and reliable histopathology image search engines for successful clinical adoption.

ExtPerFC: An Efficient 2D and 3D Perception Hardware-Software Framework for Mobile Cobot

As the reliability of the robot's perception correlates with the number of integrated sensing modalities to tackle uncertainty, a practical solution to manage these sensors from different computers, operate them simultaneously, and maintain their real-time performance on the existing robotic system with minimal effort is needed. In this work, we present an end-to-end software-hardware framework, namely ExtPerFC, that supports both conventional hardware and software components and integrates machine learning object detectors without requiring an additional dedicated graphic processor unit (GPU). We first design our framework to achieve real-time performance on the existing robotic system, guarantee configuration optimization, and concentrate on code reusability. We then mathematically model and utilize our transfer learning strategies for 2D object detection and fuse them into depth images for 3D depth estimation. Lastly, we systematically test the proposed framework on the Baxter robot with two 7-DOF arms, a four-wheel mobility base, and an Intel RealSense D435i RGB-D camera. The results show that the robot achieves real-time performance while executing other tasks (e.g., map building, localization, navigation, object detection, arm moving, and grasping) simultaneously with available hardware like Intel onboard CPUS/GPUs on distributed computers. Also, to comprehensively control, program, and monitor the robot system, we design and introduce an end-user application. The source code is available at https://github.com/tuantdang/perception_framework.

Clinically Relevant Latent Space Embedding of Cancer Histopathology Slides through Variational Autoencoder Based Image Compression

In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and decompress cancer pathology slides at a compression ratio of 1:512, which is better than the previously reported state of the art (SOTA) in the literature, while still maintaining accuracy in clinical validation tasks. The compression approach was tested on more common computer vision datasets such as CIFAR10, and we explore which image characteristics enable this compression ratio on cancer imaging data but not generic images. We generate and visualize embeddings from the compressed latent space and demonstrate how they are useful for clinical interpretation of data, and how in the future such latent embeddings can be used to accelerate search of clinical imaging data.

Generalized Reinforcement Learning: Experience Particles, Action Operator, Reinforcement Field, Memory Association, and Decision Concepts

Learning a control policy capable of adapting to time-varying and potentially evolving system dynamics has been a great challenge to the mainstream reinforcement learning (RL). Mainly, the ever-changing system properties would continuously affect how the RL agent interacts with the state space through its actions, which effectively (re-)introduces concept drifts to the underlying policy learning process. We postulated that higher adaptability for the control policy can be achieved by characterizing and representing actions with extra "degrees of freedom" and thereby, with greater flexibility, adjusts to variations from the action's "behavioral" outcomes, including how these actions get carried out in real time and the shift in the action set itself. This paper proposes a Bayesian-flavored generalized RL framework by first establishing the notion of parametric action model to better cope with uncertainty and fluid action behaviors, followed by introducing the notion of reinforcement field as a physics-inspired construct established through "polarized experience particles" maintained in the RL agent's working memory. These particles effectively encode the agent's dynamic learning experience that evolves over time in a self-organizing way. Using the reinforcement field as a substrate, we will further generalize the policy search to incorporate high-level decision concepts by viewing the past memory as an implicit graph structure, in which the memory instances, or particles, are interconnected with their degrees of associability/similarity defined and quantified such that the "associative memory" principle can be consistently applied to establish and augment the learning agent's evolving world model.

A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels

Here we present a structural similarity index measure (SSIM) guided conditional Generative Adversarial Network (cGAN) that generatively performs image-to-image (i2i) synthesis to generate photo-accurate protein channels in multiplexed spatial proteomics images. This approach can be utilized to accurately generate missing spatial proteomics channels that were not included during experimental data collection either at the bench or the clinic. Experimental spatial proteomic data from the Human BioMolecular Atlas Program (HuBMAP) was used to generate spatial representations of missing proteins through a U-Net based image synthesis pipeline. HuBMAP channels were hierarchically clustered by the (SSIM) as a heuristic to obtain the minimal set needed to recapitulate the underlying biology represented by the spatial landscape of proteins. We subsequently prove that our SSIM based architecture allows for scaling of generative image synthesis to slides with up to 100 channels, which is better than current state of the art algorithms which are limited to data with 11 channels. We validate these claims by generating a new experimental spatial proteomics data set from human lung adenocarcinoma tissue sections and show that a model trained on HuBMAP can accurately synthesize channels from our new data set. The ability to recapitulate experimental data from sparsely stained multiplexed histological slides containing spatial proteomic will have tremendous impact on medical diagnostics and drug development, and also raises important questions on the medical ethics of utilizing data produced by generative image synthesis in the clinical setting. The algorithm that we present in this paper will allow researchers and clinicians to save time and costs in proteomics based histological staining while also increasing the amount of data that they can generate through their experiments.

Increasing Fairness in Predictions Using Bias Parity Score Based Loss Function Regularization

Increasing utilization of machine learning based decision support systems emphasizes the need for resulting predictions to be both accurate and fair to all stakeholders. In this work we present a novel approach to increase a Neural Network model's fairness during training. We introduce a family of fairness enhancing regularization components that we use in conjunction with the traditional binary-cross-entropy based accuracy loss. These loss functions are based on Bias Parity Score (BPS), a score that helps quantify bias in the models with a single number. In the current work we investigate the behavior and effect of these regularization components on bias. We deploy them in the context of a recidivism prediction task as well as on a census-based adult income dataset. The results demonstrate that with a good choice of fairness loss function we can reduce the trained model's bias without deteriorating accuracy even in unbalanced dataset.