Abstract:Automatic generation of radiology reports seeks to reduce clinician workload while improving documentation consistency. Existing methods that adopt encoder-decoder or retrieval-augmented pipelines achieve progress in fluency but remain vulnerable to visual-linguistic biases, factual inconsistency, and lack of explicit multi-hop clinical reasoning. We present NeuroSymb-MRG, a unified framework that integrates NeuroSymbolic abductive reasoning with active uncertainty minimization to produce structured, clinically grounded reports. The system maps image features to probabilistic clinical concepts, composes differentiable logic-based reasoning chains, decodes those chains into templated clauses, and refines the textual output via retrieval and constrained language-model editing. An active sampling loop driven by rule-level uncertainty and diversity guides clinician-in-the-loop adjudication and promptbook refinement. Experiments on standard benchmarks demonstrate consistent improvements in factual consistency and standard language metrics compared to representative baselines.
Abstract:Repertoire-level analysis of T cell receptors offers a biologically grounded signal for disease detection and immune monitoring, yet practical deployment is impeded by label sparsity, cohort heterogeneity, and the computational burden of adapting large encoders to new tasks. We introduce a framework that synthesizes compact task-specific parameterizations from a learned dictionary of prototypes conditioned on lightweight task descriptors derived from repertoire probes and pooled embedding statistics. This synthesis produces small adapter modules applied to a frozen pretrained backbone, enabling immediate adaptation to novel tasks with only a handful of support examples and without full model fine-tuning. The architecture preserves interpretability through motif-aware probes and a calibrated motif discovery pipeline that links predictive decisions to sequence-level signals. Together, these components yield a practical, sample-efficient, and interpretable pathway for translating repertoire-informed models into diverse clinical and research settings where labeled data are scarce and computational resources are constrained.