Sparse2Inverse: Self-supervised inversion of sparse-view CT data

Sparse-view computed tomography (CT) enables fast and low-dose CT imaging, an essential feature for patient-save medical imaging and rapid non-destructive testing. In sparse-view CT, only a few projection views are acquired, causing standard reconstructions to suffer from severe artifacts and noise. To address these issues, we propose a self-supervised image reconstruction strategy. Specifically, in contrast to the established Noise2Inverse, our proposed training strategy uses a loss function in the projection domain, thereby bypassing the otherwise prescribed nullspace component. We demonstrate the effectiveness of the proposed method in reducing stripe-artifacts and noise, even from highly sparse data.

Single-Image based unsupervised joint segmentation and denoising

In this work, we develop an unsupervised method for the joint segmentation and denoising of a single image. To this end, we combine the advantages of a variational segmentation method with the power of a self-supervised, single-image based deep learning approach. One major strength of our method lies in the fact, that in contrast to data-driven methods, where huge amounts of labeled samples are necessary, our model can segment an image into multiple meaningful regions without any training database. Further, we introduce a novel energy functional in which denoising and segmentation are coupled in a way that both tasks benefit from each other. The limitations of existing single-image based variational segmentation methods, which are not capable of dealing with high noise or generic texture, are tackled by this specific combination with self-supervised image denoising. We propose a unified optimisation strategy and show that, especially for very noisy images available in microscopy, our proposed joint approach outperforms its sequential counterpart as well as alternative methods focused purely on denoising or segmentation. Another comparison is conducted with a supervised deep learning approach designed for the same application, highlighting the good performance of our approach.

Variational multichannel multiclass segmentation\endgraf using unsupervised lifting with CNNs

We propose an unsupervised image segmentation approach, that combines a variational energy functional and deep convolutional neural networks. The variational part is based on a recent multichannel multiphase Chan-Vese model, which is capable to extract useful information from multiple input images simultaneously. We implement a flexible multiclass segmentation method that divides a given image into $K$ different regions. We use convolutional neural networks (CNNs) targeting a pre-decomposition of the image. By subsequently minimising the segmentation functional, the final segmentation is obtained in a fully unsupervised manner. Special emphasis is given to the extraction of informative feature maps serving as a starting point for the segmentation. The initial results indicate that the proposed method is able to decompose and segment the different regions of various types of images, such as texture and medical images and compare its performance with another multiphase segmentation method.

A Joint Variational Multichannel Multiphase Segmentation Framework

In this paper, we propose a variational image segmentation framework for multichannel multiphase image segmentation based on the Chan-Vese active contour model. The core of our method lies in finding a variable u encoding the segmentation, by minimizing a multichannel energy functional that combines the information of multiple images. We create a decomposition of the input, either by multichannel filtering, or simply by using plain natural RGB, or medical images, which already consist of several channels. Subsequently we minimize the proposed functional for each of the channels simultaneously. Our model meets the necessary assumptions such that it can be solved efficiently by optimization techniques like the Chambolle-Pock method. We prove that the proposed energy functional has global minimizers, and show its stability and convergence with respect to noisy inputs. Experimental results show that the proposed method performs well in single- and multichannel segmentation tasks, and can be employed to the segmentation of various types of images, such as natural and texture images as well as medical images.

Sparse aNETT for Solving Inverse Problems with Deep Learning

We propose a sparse reconstruction framework (aNETT) for solving inverse problems. Opposed to existing sparse reconstruction techniques that are based on linear sparsifying transforms, we train an autoencoder network $D \circ E$ with $E$ acting as a nonlinear sparsifying transform and minimize a Tikhonov functional with learned regularizer formed by the $\ell^q$-norm of the encoder coefficients and a penalty for the distance to the data manifold. We propose a strategy for training an autoencoder based on a sample set of the underlying image class such that the autoencoder is independent of the forward operator and is subsequently adapted to the specific forward model. Numerical results are presented for sparse view CT, which clearly demonstrate the feasibility, robustness and the improved generalization capability and stability of aNETT over post-processing networks.

Deep synthesis regularization of inverse problems

Recently, a large number of efficient deep learning methods for solving inverse problems have been developed and show outstanding numerical performance. For these deep learning methods, however, a solid theoretical foundation in the form of reconstruction guarantees is missing. In contrast, for classical reconstruction methods, such as convex variational and frame-based regularization, theoretical convergence and convergence rate results are well established. In this paper, we introduce deep synthesis regularization (DESYRE) using neural networks as nonlinear synthesis operator bridging the gap between these two worlds. The proposed method allows to exploit the deep learning benefits of being well adjustable to available training data and on the other hand comes with a solid mathematical foundation. We present a complete convergence analysis with convergence rates for the proposed deep synthesis regularization. We present a strategy for constructing a synthesis network as part of an analysis-synthesis sequence together with an appropriate training strategy. Numerical results show the plausibility of our approach.

Sparse $\ell^q$-regularization of inverse problems with deep learning

We propose a sparse reconstruction framework for solving inverse problems. Opposed to existing sparse reconstruction techniques that are based on linear sparsifying transforms, we train an encoder-decoder network $D \circ E$ with $E$ acting as a nonlinear sparsifying transform. We minimize a Tikhonov functional which used a learned regularization term formed by the $\ell^q$-norm of the encoder coefficients and a penalty for the distance to the data manifold. For this augmented sparse $\ell^q$-approach, we present a full convergence analysis, derive convergence rates and describe a training strategy. As a main ingredient for the analysis we establish the coercivity of the augmented regularization term.

NETT: Solving Inverse Problems with Deep Neural Networks

Recovering a function or high-dimensional parameter vector from indirect measurements is a central task in various scientific areas. Several methods for solving such inverse problems are well developed and well understood. Recently, novel algorithms using deep learning and neural networks for inverse problems appeared. While still in their infancy, these techniques show astonishing performance for applications like low-dose CT or various sparse data problems. However, theoretical results for deep learning in inverse problems are missing so far. In this paper, we establish such a convergence analysis for the proposed NETT (Network Tikhonov) approach to inverse problems. NETT considers regularized solutions having small value of a regularizer defined by a trained neural network. Opposed to existing deep learning approaches, our regularization scheme enforces data consistency also for the actual unknown to be recovered. This is beneficial in case the unknown to be recovered is not sufficiently similar to available training data. We present a complete convergence analysis for NETT, where we derive well-posedness results and quantitative error estimates, and propose a possible strategy for training the regularizer. Numerical results are presented for a tomographic sparse data problem using the $\ell^q$-norm of auto-encoder as trained regularizer, which demonstrate good performance of NETT even for unknowns of different type from the training data.