PathMem: Toward Cognition-Aligned Memory Transformation for Pathology MLLMs

Computational pathology demands both visual pattern recognition and dynamic integration of structured domain knowledge, including taxonomy, grading criteria, and clinical evidence. In practice, diagnostic reasoning requires linking morphological evidence with formal diagnostic and grading criteria. Although multimodal large language models (MLLMs) demonstrate strong vision language reasoning capabilities, they lack explicit mechanisms for structured knowledge integration and interpretable memory control. As a result, existing models struggle to consistently incorporate pathology-specific diagnostic standards during reasoning. Inspired by the hierarchical memory process of human pathologists, we propose PathMem, a memory-centric multimodal framework for pathology MLLMs. PathMem organizes structured pathology knowledge as a long-term memory (LTM) and introduces a Memory Transformer that models the dynamic transition from LTM to working memory (WM) through multimodal memory activation and context-aware knowledge grounding, enabling context-aware memory refinement for downstream reasoning. PathMem achieves SOTA performance across benchmarks, improving WSI-Bench report generation (12.8% WSI-Precision, 10.1% WSI-Relevance) and open-ended diagnosis by 9.7% and 8.9% over prior WSI-based models.

Adversarial Robustness in Unsupervised Machine Learning: A Systematic Review

As the adoption of machine learning models increases, ensuring robust models against adversarial attacks is increasingly important. With unsupervised machine learning gaining more attention, ensuring it is robust against attacks is vital. This paper conducts a systematic literature review on the robustness of unsupervised learning, collecting 86 papers. Our results show that most research focuses on privacy attacks, which have effective defenses; however, many attacks lack effective and general defensive measures. Based on the results, we formulate a model on the properties of an attack on unsupervised learning, contributing to future research by providing a model to use.