Toward a Team of AI-made Scientists for Scientific Discovery from Gene Expression Data

Machine learning has emerged as a powerful tool for scientific discovery, enabling researchers to extract meaningful insights from complex datasets. For instance, it has facilitated the identification of disease-predictive genes from gene expression data, significantly advancing healthcare. However, the traditional process for analyzing such datasets demands substantial human effort and expertise for the data selection, processing, and analysis. To address this challenge, we introduce a novel framework, a Team of AI-made Scientists (TAIS), designed to streamline the scientific discovery pipeline. TAIS comprises simulated roles, including a project manager, data engineer, and domain expert, each represented by a Large Language Model (LLM). These roles collaborate to replicate the tasks typically performed by data scientists, with a specific focus on identifying disease-predictive genes. Furthermore, we have curated a benchmark dataset to assess TAIS's effectiveness in gene identification, demonstrating our system's potential to significantly enhance the efficiency and scope of scientific exploration. Our findings represent a solid step towards automating scientific discovery through large language models.

Challenges and approaches for mitigating byzantine attacks in federated learning

Recently emerged federated learning (FL) is an attractive distributed learning framework in which numerous wireless end-user devices can train a global model with the data remained autochthonous. Compared with the traditional machine learning framework that collects user data for centralized storage, which brings huge communication burden and concerns about data privacy, this approach can not only save the network bandwidth but also protect the data privacy. Despite the promising prospect, byzantine attack, an intractable threat in conventional distributed network, is discovered to be rather efficacious against FL as well. In this paper, we conduct a comprehensive investigation of the state-of-the-art strategies for defending against byzantine attacks in FL. We first provide a taxonomy for the existing defense solutions according to the techniques they used, followed by an across-the-board comparison and discussion. Then we propose a new byzantine attack method called weight attack to defeat those defense schemes, and conduct experiments to demonstrate its threat. The results show that existing defense solutions, although abundant, are still far from fully protecting FL. Finally, we indicate possible countermeasures for weight attack, and highlight several challenges and future research directions for mitigating byzantine attacks in FL.