MAESIL: Masked Autoencoder for Enhanced Self-supervised Medical Image Learning

Training deep learning models for three-dimensional (3D) medical imaging, such as Computed Tomography (CT), is fundamentally challenged by the scarcity of labeled data. While pre-training on natural images is common, it results in a significant domain shift, limiting performance. Self-Supervised Learning (SSL) on unlabeled medical data has emerged as a powerful solution, but prominent frameworks often fail to exploit the inherent 3D nature of CT scans. These methods typically process 3D scans as a collection of independent 2D slices, an approach that fundamentally discards critical axial coherence and the 3D structural context. To address this limitation, we propose the autoencoder for enhanced self-supervised medical image learning(MAESIL), a novel self-supervised learning framework designed to capture 3D structural information efficiently. The core innovation is the 'superpatch', a 3D chunk-based input unit that balances 3D context preservation with computational efficiency. Our framework partitions the volume into superpatches and employs a 3D masked autoencoder strategy with a dual-masking strategy to learn comprehensive spatial representations. We validated our approach on three diverse large-scale public CT datasets. Our experimental results show that MAESIL demonstrates significant improvements over existing methods such as AE, VAE and VQ-VAE in key reconstruction metrics such as PSNR and SSIM. This establishes MAESIL as a robust and practical pre-training solution for 3D medical imaging tasks.

MATHENA: Mamba-based Architectural Tooth Hierarchical Estimator and Holistic Evaluation Network for Anatomy

Dental diagnosis from Orthopantomograms (OPGs) requires coordination of tooth detection, caries segmentation (CarSeg), anomaly detection (AD), and dental developmental staging (DDS). We propose Mamba-based Architectural Tooth Hierarchical Estimator and Holistic Evaluation Network for Anatomy (MATHENA), a unified framework leveraging Mamba's linear-complexity State Space Models (SSM) to address all four tasks. MATHENA integrates MATHE, a multi-resolution SSM-driven detector with four-directional Vision State Space (VSS) blocks for O(N) global context modeling, generating per-tooth crops. These crops are processed by HENA, a lightweight Mamba-UNet with a triple-head architecture and Global Context State Token (GCST). In the triple-head architecture, CarSeg is first trained as an upstream task to establish shared representations, which are then frozen and reused for downstream AD fine-tuning and DDS classification via linear probing, enabling stable, efficient learning. We also curate PARTHENON, a benchmark comprising 15,062 annotated instances from ten datasets. MATHENA achieves 93.78% mAP@50 in tooth detection, 90.11% Dice for CarSeg, 88.35% for AD, and 72.40% ACC for DDS.

COTTA: Context-Aware Transfer Adaptation for Trajectory Prediction in Autonomous Driving

Developing robust models to accurately predict the trajectories of surrounding agents is fundamental to autonomous driving safety. However, most public datasets, such as the Waymo Open Motion Dataset and Argoverse, are collected in Western road environments and do not reflect the unique traffic patterns, infrastructure, and driving behaviors of other regions, including South Korea. This domain discrepancy leads to performance degradation when state-of-the-art models trained on Western data are deployed in different geographic contexts. In this work, we investigate the adaptability of Query-Centric Trajectory Prediction (QCNet) when transferred from U.S.-based data to Korean road environments. Using a Korean autonomous driving dataset, we compare four training strategies: zero-shot transfer, training from scratch, full fine-tuning, and encoder freezing. Experimental results demonstrate that leveraging pretrained knowledge significantly improves prediction performance. Specifically, selectively fine-tuning the decoder while freezing the encoder yields the best trade-off between accuracy and training efficiency, reducing prediction error by over 66% compared to training from scratch. This study provides practical insights into effective transfer learning strategies for deploying trajectory prediction models in new geographic domains.

NeoNet: An End-to-End 3D MRI-Based Deep Learning Framework for Non-Invasive Prediction of Perineural Invasion via Generation-Driven Classification

Minimizing invasive diagnostic procedures to reduce the risk of patient injury and infection is a central goal in medical imaging. And yet, noninvasive diagnosis of perineural invasion (PNI), a critical prognostic factor involving infiltration of tumor cells along the surrounding nerve, still remains challenging, due to the lack of clear and consistent imaging criteria criteria for identifying PNI. To address this challenge, we present NeoNet, an integrated end-to-end 3D deep learning framework for PNI prediction in cholangiocarcinoma that does not rely on predefined image features. NeoNet integrates three modules: (1) NeoSeg, utilizing a Tumor-Localized ROI Crop (TLCR) algorithm; (2) NeoGen, a 3D Latent Diffusion Model (LDM) with ControlNet, conditioned on anatomical masks to generate synthetic image patches, specifically balancing the dataset to a 1:1 ratio; and (3) NeoCls, the final prediction module. For NeoCls, we developed the PNI-Attention Network (PattenNet), which uses the frozen LDM encoder and specialized 3D Dual Attention Blocks (DAB) designed to detect subtle intensity variations and spatial patterns indicative of PNI. In 5-fold cross-validation, NeoNet outperformed baseline 3D models and achieved the highest performance with a maximum AUC of 0.7903.

FOSCU: Feasibility of Synthetic MRI Generation via Duo-Diffusion Models for Enhancement of 3D U-Nets in Hepatic Segmentation

Medical image segmentation faces fundamental challenges including restricted access, costly annotation, and data shortage to clinical datasets through Picture Archiving and Communication Systems (PACS). These systemic barriers significantly impede the development of robust segmentation algorithms. To address these challenges, we propose FOSCU, which integrates Duo-Diffusion, a 3D latent diffusion model with ControlNet that simultaneously generates high-resolution, anatomically realistic synthetic MRI volumes and corresponding segmentation labels, and an enhanced 3D U-Net training pipeline. Duo-Diffusion employs segmentation-conditioned diffusion to ensure spatial consistency and precise anatomical detail in the generated data. Experimental evaluation on 720 abdominal MRI scans shows that models trained with combined real and synthetic data yield a mean Dice score gain of 0.67% over those using only real data, and achieve a 36.4% reduction in Fréchet Inception Distance (FID), reflecting enhanced image fidelity.

CIPHER: Counterfeit Image Pattern High-level Examination via Representation

The rapid progress of generative adversarial networks (GANs) and diffusion models has enabled the creation of synthetic faces that are increasingly difficult to distinguish from real images. This progress, however, has also amplified the risks of misinformation, fraud, and identity abuse, underscoring the urgent need for detectors that remain robust across diverse generative models. In this work, we introduce Counterfeit Image Pattern High-level Examination via Representation(CIPHER), a deepfake detection framework that systematically reuses and fine-tunes discriminators originally trained for image generation. By extracting scale-adaptive features from ProGAN discriminators and temporal-consistency features from diffusion models, CIPHER captures generation-agnostic artifacts that conventional detectors often overlook. Through extensive experiments across nine state-of-the-art generative models, CIPHER demonstrates superior cross-model detection performance, achieving up to 74.33% F1-score and outperforming existing ViT-based detectors by over 30% in F1-score on average. Notably, our approach maintains robust performance on challenging datasets where baseline methods fail, with up to 88% F1-score on CIFAKE compared to near-zero performance from conventional detectors. These results validate the effectiveness of discriminator reuse and cross-model fine-tuning, establishing CIPHER as a promising approach toward building more generalizable and robust deepfake detection systems in an era of rapidly evolving generative technologies.

3D-LLDM: Label-Guided 3D Latent Diffusion Model for Improving High-Resolution Synthetic MR Imaging in Hepatic Structure Segmentation

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the scarcity of reliable annotated datasets. To address this limitation, we propose 3D-LLDM, a label-guided 3D latent diffusion model that generates high-quality synthetic magnetic resonance (MR) volumes with corresponding anatomical segmentation masks. Our approach uses hepatobiliary phase MR images enhanced with the Gd-EOB-DTPA contrast agent to derive structural masks for the liver, portal vein, hepatic vein, and hepatocellular carcinoma, which then guide volumetric synthesis through a ControlNet-based architecture. Trained on 720 real clinical hepatobiliary phase MR scans from Samsung Medical Center, 3D-LLDM achieves a Fréchet Inception Distance (FID) of 28.31, improving over GANs by 70.9% and over state-of-the-art diffusion baselines by 26.7%. When used for data augmentation, the synthetic volumes improve hepatocellular carcinoma segmentation by up to 11.153% Dice score across five CNN architectures.

Whisfusion: Parallel ASR Decoding via a Diffusion Transformer

Fast Automatic Speech Recognition (ASR) is critical for latency-sensitive applications such as real-time captioning and meeting transcription. However, truly parallel ASR decoding remains challenging due to the sequential nature of autoregressive (AR) decoders and the context limitations of non-autoregressive (NAR) methods. While modern ASR encoders can process up to 30 seconds of audio at once, AR decoders still generate tokens sequentially, creating a latency bottleneck. We propose Whisfusion, the first framework to fuse a pre-trained Whisper encoder with a text diffusion decoder. This NAR architecture resolves the AR latency bottleneck by processing the entire acoustic context in parallel at every decoding step. A lightweight cross-attention adapter trained via parameter-efficient fine-tuning (PEFT) bridges the two modalities. We also introduce a batch-parallel, multi-step decoding strategy that improves accuracy by increasing the number of candidates with minimal impact on speed. Fine-tuned solely on LibriSpeech (960h), Whisfusion achieves a lower WER than Whisper-tiny (8.3% vs. 9.7%), and offers comparable latency on short audio. For longer utterances (>20s), it is up to 2.6x faster than the AR baseline, establishing a new, efficient operating point for long-form ASR. The implementation and training scripts are available at https://github.com/taeyoun811/Whisfusion.

MathSpeech: Leveraging Small LMs for Accurate Conversion in Mathematical Speech-to-Formula

In various academic and professional settings, such as mathematics lectures or research presentations, it is often necessary to convey mathematical expressions orally. However, reading mathematical expressions aloud without accompanying visuals can significantly hinder comprehension, especially for those who are hearing-impaired or rely on subtitles due to language barriers. For instance, when a presenter reads Euler's Formula, current Automatic Speech Recognition (ASR) models often produce a verbose and error-prone textual description (e.g., e to the power of i x equals cosine of x plus i $\textit{side}$ of x), instead of the concise $\LaTeX{}$ format (i.e., $ e^{ix} = \cos(x) + i\sin(x) $), which hampers clear understanding and communication. To address this issue, we introduce MathSpeech, a novel pipeline that integrates ASR models with small Language Models (sLMs) to correct errors in mathematical expressions and accurately convert spoken expressions into structured $\LaTeX{}$ representations. Evaluated on a new dataset derived from lecture recordings, MathSpeech demonstrates $\LaTeX{}$ generation capabilities comparable to leading commercial Large Language Models (LLMs), while leveraging fine-tuned small language models of only 120M parameters. Specifically, in terms of CER, BLEU, and ROUGE scores for $\LaTeX{}$ translation, MathSpeech demonstrated significantly superior capabilities compared to GPT-4o. We observed a decrease in CER from 0.390 to 0.298, and higher ROUGE/BLEU scores compared to GPT-4o.

MathBridge: A Large Corpus Dataset for Translating Spoken Mathematical Expressions into $LaTeX$ Formulas for Improved Readability

Understanding sentences that contain mathematical expressions in text form poses significant challenges. To address this, the importance of converting these expressions into a compiled formula is highlighted. For instance, the expression ``x equals minus b plus or minus the square root of b squared minus four a c, all over two a'' from automatic speech recognition (ASR) is more readily comprehensible when displayed as a compiled formula $x = \frac{-b \pm \sqrt{b^2 - 4ac}}{2a}$. To develop a text-to-formula conversion system, we can break down the process into text-to-LaTeX and LaTeX-to-formula conversions, with the latter managed by various existing LaTeX engines. However, the former approach has been notably hindered by the severe scarcity of text-to-LaTeX paired data, which presents a significant challenge in this field. In this context, we introduce MathBridge, the first extensive dataset for translating mathematical spoken expressions into LaTeX, to establish a robust baseline for future research on text-to-LaTeX translation. MathBridge comprises approximately 23 million LaTeX formulas paired with the corresponding spoken English expressions. Through comprehensive evaluations, including fine-tuning and testing with data, we discovered that MathBridge significantly enhances the capabilities of pretrained language models for text-to-LaTeX translation. Specifically, for the T5-large model, the sacreBLEU score increased from 4.77 to 46.8, demonstrating substantial enhancement. Our findings indicate the need for a new metric, specifically for text-to-LaTeX conversion evaluations.