LoSA-Net: A Localized and Scale-Adaptive Network for Boundary-Sensitive Prediction of Perineural Invasion in 3D MRI

Perineural invasion (PNI) is a clinically relevant indicator of tumor aggressiveness and can influence surgical decision-making, motivating interest in reliable preoperative assessment. The subtle MRI features of PNI, however, often resemble nearby anatomy, complicating noninvasive prediction. These fine perineural cues are easily attenuated by routine downsampling or overly global feature aggregation, reducing the effectiveness of conventional volumetric models. We present LoSA-Net, a localized and scale-adaptive architecture for boundary-sensitive PNI prediction in 3D MRI. Talking Neighborhood Attention (TNA) preserves nerve-aligned detail through localized self-attention with head-wise mixing, and Scale-Adaptive Feature Mixing (SAFM) modulates the receptive field using multi-scale depthwise processing. Cross-Scale Refinement and Alignment (CSRA) maintains consistency between semantic context and high-resolution boundaries across stages. In contrast-enhanced MRI scans from 168 patients with cholangiocarcinoma, LoSA-Net achieves an AUC of 0.7567 and outperforms representative convolutional and transformer baselines under matched preprocessing and optimization settings.

MMA-Former: Multi-Window Mixture-of-Head Attention Transformer for Adaptive PNI Prediction in 3D MRI

Perineural invasion (PNI) is a critical prognostic factor in cholangiocarcinoma. Non-invasive prediction from 3D MRI is challenging, demanding models that efficiently capture both fine-grained details and global context. We propose the Multi-window Mixture-of-Head Attention Transformer (MMA-Former), a novel end-to-end 3D architecture featuring a Coarse-Fine Transformer (CFT) structure for parallel multi-scale feature extraction. We advance this structure by integrating a novel Window-Specific Mixture-of-Head attention (WS-MoH) mechanism. Unlike standard Multi-Head Self Attention (MSA), WS-MoH generates a representation for each 3D window and dynamically routes the entire window to specialized or common attention heads. This enables spatially adaptive feature extraction tailored to the local context of each window, enhancing specialization and reducing redundancy without increasing parameters. Evaluated on a retrospective dataset of 168 T1-weighted MRI scans, MMA-Former achieved an AUC of 0.752, outperforming other 3D architectures, including the best CNN (AUC of 0.708) and Transformer baselines (AUC of 0.681).

NeoNet: An End-to-End 3D MRI-Based Deep Learning Framework for Non-Invasive Prediction of Perineural Invasion via Generation-Driven Classification

Minimizing invasive diagnostic procedures to reduce the risk of patient injury and infection is a central goal in medical imaging. And yet, noninvasive diagnosis of perineural invasion (PNI), a critical prognostic factor involving infiltration of tumor cells along the surrounding nerve, still remains challenging, due to the lack of clear and consistent imaging criteria criteria for identifying PNI. To address this challenge, we present NeoNet, an integrated end-to-end 3D deep learning framework for PNI prediction in cholangiocarcinoma that does not rely on predefined image features. NeoNet integrates three modules: (1) NeoSeg, utilizing a Tumor-Localized ROI Crop (TLCR) algorithm; (2) NeoGen, a 3D Latent Diffusion Model (LDM) with ControlNet, conditioned on anatomical masks to generate synthetic image patches, specifically balancing the dataset to a 1:1 ratio; and (3) NeoCls, the final prediction module. For NeoCls, we developed the PNI-Attention Network (PattenNet), which uses the frozen LDM encoder and specialized 3D Dual Attention Blocks (DAB) designed to detect subtle intensity variations and spatial patterns indicative of PNI. In 5-fold cross-validation, NeoNet outperformed baseline 3D models and achieved the highest performance with a maximum AUC of 0.7903.

LLM-guided Plan and Retrieval: A Strategic Alignment for Interpretable User Satisfaction Estimation in Dialogue

Understanding user satisfaction with conversational systems, known as User Satisfaction Estimation (USE), is essential for assessing dialogue quality and enhancing user experiences. However, existing methods for USE face challenges due to limited understanding of underlying reasons for user dissatisfaction and the high costs of annotating user intentions. To address these challenges, we propose PRAISE (Plan and Retrieval Alignment for Interpretable Satisfaction Estimation), an interpretable framework for effective user satisfaction prediction. PRAISE operates through three key modules. The Strategy Planner develops strategies, which are natural language criteria for classifying user satisfaction. The Feature Retriever then incorporates knowledge on user satisfaction from Large Language Models (LLMs) and retrieves relevance features from utterances. Finally, the Score Analyzer evaluates strategy predictions and classifies user satisfaction. Experimental results demonstrate that PRAISE achieves state-of-the-art performance on three benchmarks for the USE task. Beyond its superior performance, PRAISE offers additional benefits. It enhances interpretability by providing instance-level explanations through effective alignment of utterances with strategies. Moreover, PRAISE operates more efficiently than existing approaches by eliminating the need for LLMs during the inference phase.

Safe-Embed: Unveiling the Safety-Critical Knowledge of Sentence Encoders

Despite the impressive capabilities of Large Language Models (LLMs) in various tasks, their vulnerability to unsafe prompts remains a critical issue. These prompts can lead LLMs to generate responses on illegal or sensitive topics, posing a significant threat to their safe and ethical use. Existing approaches attempt to address this issue using classification models, but they have several drawbacks. With the increasing complexity of unsafe prompts, similarity search-based techniques that identify specific features of unsafe prompts provide a more robust and effective solution to this evolving problem. This paper investigates the potential of sentence encoders to distinguish safe from unsafe prompts, and the ability to classify various unsafe prompts according to a safety taxonomy. We introduce new pairwise datasets and the Categorical Purity (CP) metric to measure this capability. Our findings reveal both the effectiveness and limitations of existing sentence encoders, proposing directions to improve sentence encoders to operate as more robust safety detectors. Our code is available at https://github.com/JwdanielJung/Safe-Embed.

Pipette: Automatic Fine-grained Large Language Model Training Configurator for Real-World Clusters

Training large language models (LLMs) is known to be challenging because of the huge computational and memory capacity requirements. To address these issues, it is common to use a cluster of GPUs with 3D parallelism, which splits a model along the data batch, pipeline stage, and intra-layer tensor dimensions. However, the use of 3D parallelism produces the additional challenge of finding the optimal number of ways on each dimension and mapping the split models onto the GPUs. Several previous studies have attempted to automatically find the optimal configuration, but many of these lacked several important aspects. For instance, the heterogeneous nature of the interconnect speeds is often ignored. While the peak bandwidths for the interconnects are usually made equal, the actual attained bandwidth varies per link in real-world clusters. Combined with the critical path modeling that does not properly consider the communication, they easily fall into sub-optimal configurations. In addition, they often fail to consider the memory requirement per GPU, often recommending solutions that could not be executed. To address these challenges, we propose Pipette, which is an automatic fine-grained LLM training configurator for real-world clusters. By devising better performance models along with the memory estimator and fine-grained individual GPU assignment, Pipette achieves faster configurations that satisfy the memory constraints. We evaluated Pipette on large clusters to show that it provides a significant speedup over the prior art. The implementation of Pipette is available at https://github.com/yimjinkyu1/date2024_pipette.

Smart-Infinity: Fast Large Language Model Training using Near-Storage Processing on a Real System

The recent huge advance of Large Language Models (LLMs) is mainly driven by the increase in the number of parameters. This has led to substantial memory capacity requirements, necessitating the use of dozens of GPUs just to meet the capacity. One popular solution to this is storage-offloaded training, which uses host memory and storage as an extended memory hierarchy. However, this obviously comes at the cost of storage bandwidth bottleneck because storage devices have orders of magnitude lower bandwidth compared to that of GPU device memories. Our work, Smart-Infinity, addresses the storage bandwidth bottleneck of storage-offloaded LLM training using near-storage processing devices on a real system. The main component of Smart-Infinity is SmartUpdate, which performs parameter updates on custom near-storage accelerators. We identify that moving parameter updates to the storage side removes most of the storage traffic. In addition, we propose an efficient data transfer handler structure to address the system integration issues for Smart-Infinity. The handler allows overlapping data transfers with fixed memory consumption by reusing the device buffer. Lastly, we propose accelerator-assisted gradient compression/decompression to enhance the scalability of Smart-Infinity. When scaling to multiple near-storage processing devices, the write traffic on the shared channel becomes the bottleneck. To alleviate this, we compress the gradients on the GPU and decompress them on the accelerators. It provides further acceleration from reduced traffic. As a result, Smart-Infinity achieves a significant speedup compared to the baseline. Notably, Smart-Infinity is a ready-to-use approach that is fully integrated into PyTorch on a real system. We will open-source Smart-Infinity to facilitate its use.

PeerAiD: Improving Adversarial Distillation from a Specialized Peer Tutor

Adversarial robustness of the neural network is a significant concern when it is applied to security-critical domains. In this situation, adversarial distillation is a promising option which aims to distill the robustness of the teacher network to improve the robustness of a small student network. Previous works pretrain the teacher network to make it robust to the adversarial examples aimed at itself. However, the adversarial examples are dependent on the parameters of the target network. The fixed teacher network inevitably degrades its robustness against the unseen transferred adversarial examples which targets the parameters of the student network in the adversarial distillation process. We propose PeerAiD to make a peer network learn the adversarial examples of the student network instead of adversarial examples aimed at itself. PeerAiD is an adversarial distillation that trains the peer network and the student network simultaneously in order to make the peer network specialized for defending the student network. We observe that such peer networks surpass the robustness of pretrained robust teacher network against student-attacked adversarial samples. With this peer network and adversarial distillation, PeerAiD achieves significantly higher robustness of the student network with AutoAttack (AA) accuracy up to 1.66%p and improves the natural accuracy of the student network up to 4.72%p with ResNet-18 and TinyImageNet dataset.

GraNNDis: Efficient Unified Distributed Training Framework for Deep GNNs on Large Clusters

Graph neural networks (GNNs) are one of the most rapidly growing fields within deep learning. According to the growth in the dataset and the model size used for GNNs, an important problem is that it becomes nearly impossible to keep the whole network on GPU memory. Among numerous attempts, distributed training is one popular approach to address the problem. However, due to the nature of GNNs, existing distributed approaches suffer from poor scalability, mainly due to the slow external server communications. In this paper, we propose GraNNDis, an efficient distributed GNN training framework for training GNNs on large graphs and deep layers. GraNNDis introduces three new techniques. First, shared preloading provides a training structure for a cluster of multi-GPU servers. We suggest server-wise preloading of essential vertex dependencies to reduce the low-bandwidth external server communications. Second, we present expansion-aware sampling. Because shared preloading alone has limitations because of the neighbor explosion, expansion-aware sampling reduces vertex dependencies that span across server boundaries. Third, we propose cooperative batching to create a unified framework for full-graph and minibatch training. It significantly reduces redundant memory usage in mini-batch training. From this, GraNNDis enables a reasonable trade-off between full-graph and mini-batch training through unification especially when the entire graph does not fit into the GPU memory. With experiments conducted on a multi-server/multi-GPU cluster, we show that GraNNDis provides superior speedup over the state-of-the-art distributed GNN training frameworks.

Pipe-BD: Pipelined Parallel Blockwise Distillation

Training large deep neural network models is highly challenging due to their tremendous computational and memory requirements. Blockwise distillation provides one promising method towards faster convergence by splitting a large model into multiple smaller models. In state-of-the-art blockwise distillation methods, training is performed block-by-block in a data-parallel manner using multiple GPUs. To produce inputs for the student blocks, the teacher model is executed from the beginning until the current block under training. However, this results in a high overhead of redundant teacher execution, low GPU utilization, and extra data loading. To address these problems, we propose Pipe-BD, a novel parallelization method for blockwise distillation. Pipe-BD aggressively utilizes pipeline parallelism for blockwise distillation, eliminating redundant teacher block execution and increasing per-device batch size for better resource utilization. We also extend to hybrid parallelism for efficient workload balancing. As a result, Pipe-BD achieves significant acceleration without modifying the mathematical formulation of blockwise distillation. We implement Pipe-BD on PyTorch, and experiments reveal that Pipe-BD is effective on multiple scenarios, models, and datasets.