The First AI4TSP Competition: Learning to Solve Stochastic Routing Problems

This paper reports on the first international competition on AI for the traveling salesman problem (TSP) at the International Joint Conference on Artificial Intelligence 2021 (IJCAI-21). The TSP is one of the classical combinatorial optimization problems, with many variants inspired by real-world applications. This first competition asked the participants to develop algorithms to solve a time-dependent orienteering problem with stochastic weights and time windows (TD-OPSWTW). It focused on two types of learning approaches: surrogate-based optimization and deep reinforcement learning. In this paper, we describe the problem, the setup of the competition, the winning methods, and give an overview of the results. The winning methods described in this work have advanced the state-of-the-art in using AI for stochastic routing problems. Overall, by organizing this competition we have introduced routing problems as an interesting problem setting for AI researchers. The simulator of the problem has been made open-source and can be used by other researchers as a benchmark for new AI methods.

A Reinforcement Learning Approach to the Orienteering Problem with Time Windows

The Orienteering Problem with Time Windows (OPTW) is a combinatorial optimization problem where the goal is to maximize the total scores collected from visited locations, under some time constraints. Several heuristics have been proposed for the OPTW, yet in comparison with machine learning models, a heuristic typically has a smaller potential for generalization and personalization. The application of neural network models to combinatorial optimization has recently shown promising results in similar problems like the Travelling Salesman Problem. A neural network allows learning solutions using reinforcement learning or in a supervised way, depending on the available data. After learning, it can potentially generalize and be quickly fine-tuned to further improve performance and personalization. This is advantageous since, for real word applications, a solution's quality, personalization and execution times are all important factors to be taken into account. Here we explore the use of Pointer Network models trained with reinforcement learning for solving the OPTW problem. Among its various applications, the OPTW can be used to model the Tourist Trip Design Problem (TTDP). We train the Pointer Network with the TTDP problem in mind, by sampling variables that can change across tourists for a particular instance-region: starting position, starting time, time available and the scores of each point of interest. After a model-region is trained it can infer a solution for a particular tourist using beam search. We evaluate our approach on several existing benchmark OPTW instances. We show that it is able to generalize across different generated tourists for each region and that it generally outperforms the most commonly used heuristic while computing the solution in realistic times.

Quantifying mesoscale neuroanatomy using X-ray microtomography

Methods for resolving the 3D microstructure of the brain typically start by thinly slicing and staining the brain, and then imaging each individual section with visible light photons or electrons. In contrast, X-rays can be used to image thick samples, providing a rapid approach for producing large 3D brain maps without sectioning. Here we demonstrate the use of synchrotron X-ray microtomography ($\mu$CT) for producing mesoscale $(1~\mu m^3)$ resolution brain maps from millimeter-scale volumes of mouse brain. We introduce a pipeline for $\mu$CT-based brain mapping that combines methods for sample preparation, imaging, automated segmentation of image volumes into cells and blood vessels, and statistical analysis of the resulting brain structures. Our results demonstrate that X-ray tomography promises rapid quantification of large brain volumes, complementing other brain mapping and connectomics efforts.