M3BUNet: Mobile Mean Max UNet for Pancreas Segmentation on CT-Scans

Segmenting organs in CT scan images is a necessary process for multiple downstream medical image analysis tasks. Currently, manual CT scan segmentation by radiologists is prevalent, especially for organs like the pancreas, which requires a high level of domain expertise for reliable segmentation due to factors like small organ size, occlusion, and varying shapes. When resorting to automated pancreas segmentation, these factors translate to limited reliable labeled data to train effective segmentation models. Consequently, the performance of contemporary pancreas segmentation models is still not within acceptable ranges. To improve that, we propose M3BUNet, a fusion of MobileNet and U-Net neural networks, equipped with a novel Mean-Max (MM) attention that operates in two stages to gradually segment pancreas CT images from coarse to fine with mask guidance for object detection. This approach empowers the network to surpass segmentation performance achieved by similar network architectures and achieve results that are on par with complex state-of-the-art methods, all while maintaining a low parameter count. Additionally, we introduce external contour segmentation as a preprocessing step for the coarse stage to assist in the segmentation process through image standardization. For the fine segmentation stage, we found that applying a wavelet decomposition filter to create multi-input images enhances pancreas segmentation performance. We extensively evaluate our approach on the widely known NIH pancreas dataset and MSD pancreas dataset. Our approach demonstrates a considerable performance improvement, achieving an average Dice Similarity Coefficient (DSC) value of up to 89.53% and an Intersection Over Union (IOU) score of up to 81.16 for the NIH pancreas dataset, and 88.60% DSC and 79.90% IOU for the MSD Pancreas dataset.

Multimodal Neuroimaging Attention-Based architecture for Cognitive Decline Prediction

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI). However, there is very small literature in predicting the conversion to AD and MCI from normal cognitive condition. Recently, multiple studies have applied convolutional neural networks (CNN) which integrate Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) to classify MCI and AD. However, in these works, the fusion of MRI and PET features are simply achieved through concatenation, resulting in a lack of cross-modal interactions. In this paper, we propose a novel multimodal neuroimaging attention-based CNN architecture, MNA-net, to predict whether cognitively normal (CN) individuals will develop MCI or AD within a period of 10 years. To address the lack of interactions across neuroimaging modalities seen in previous works, MNA-net utilises attention mechanisms to form shared representations of the MRI and PET images. The proposed MNA-net is tested in OASIS-3 dataset and is able to predict CN individuals who converted to MCI or AD with an accuracy of 83%, true negative rate of 80%, and true positive rate of 86%. The new state of the art results improved by 5% and 10% for accuracy and true negative rate by the use of attention mechanism. These results demonstrate the potential of the proposed model to predict cognitive impairment and attention based mechanisms in the fusion of different neuroimaging modalities to improve the prediction of cognitive decline.

COVID-19 Detection System: A Comparative Analysis of System Performance Based on Acoustic Features of Cough Audio Signals

A wide range of respiratory diseases, such as cold and flu, asthma, and COVID-19, affect people's daily lives worldwide. In medical practice, respiratory sounds are widely used in medical services to diagnose various respiratory illnesses and lung disorders. The traditional diagnosis of such sounds requires specialized knowledge, which can be costly and reliant on human expertise. Recently, cough audio recordings have been used to automate the process of detecting respiratory conditions. This research aims to examine various acoustic features that enhance the performance of machine learning (ML) models in detecting COVID-19 from cough signals. This study investigates the efficacy of three feature extraction techniques, including Mel Frequency Cepstral Coefficients (MFCC), Chroma, and Spectral Contrast features, on two ML algorithms, Support Vector Machine (SVM) and Multilayer Perceptron (MLP), and thus proposes an efficient COVID-19 detection system. The proposed system produces a practical solution and demonstrates higher state-of-the-art classification performance on COUGHVID and Virufy datasets for COVID-19 detection.

SCOL: Supervised Contrastive Ordinal Loss for Abdominal Aortic Calcification Scoring on Vertebral Fracture Assessment Scans

Abdominal Aortic Calcification (AAC) is a known marker of asymptomatic Atherosclerotic Cardiovascular Diseases (ASCVDs). AAC can be observed on Vertebral Fracture Assessment (VFA) scans acquired using Dual-Energy X-ray Absorptiometry (DXA) machines. Thus, the automatic quantification of AAC on VFA DXA scans may be used to screen for CVD risks, allowing early interventions. In this research, we formulate the quantification of AAC as an ordinal regression problem. We propose a novel Supervised Contrastive Ordinal Loss (SCOL) by incorporating a label-dependent distance metric with existing supervised contrastive loss to leverage the ordinal information inherent in discrete AAC regression labels. We develop a Dual-encoder Contrastive Ordinal Learning (DCOL) framework that learns the contrastive ordinal representation at global and local levels to improve the feature separability and class diversity in latent space among the AAC-24 genera. We evaluate the performance of the proposed framework using two clinical VFA DXA scan datasets and compare our work with state-of-the-art methods. Furthermore, for predicted AAC scores, we provide a clinical analysis to predict the future risk of a Major Acute Cardiovascular Event (MACE). Our results demonstrate that this learning enhances inter-class separability and strengthens intra-class consistency, which results in predicting the high-risk AAC classes with high sensitivity and high accuracy.

Classification of sleep stages from EEG, EOG and EMG signals by SSNet

Classification of sleep stages plays an essential role in diagnosing sleep-related diseases including Sleep Disorder Breathing (SDB) disease. In this study, we propose an end-to-end deep learning architecture, named SSNet, which comprises of two deep learning networks based on Convolutional Neuron Networks (CNN) and Long Short Term Memory (LSTM). Both deep learning networks extract features from the combination of Electrooculogram (EOG), Electroencephalogram (EEG), and Electromyogram (EMG) signals, as each signal has distinct features that help in the classification of sleep stages. The features produced by the two-deep learning networks are concatenated to pass to the fully connected layer for the classification. The performance of our proposed model is evaluated by using two public datasets Sleep-EDF Expanded dataset and ISRUC-Sleep dataset. The accuracy and Kappa coefficient are 96.36% and 93.40% respectively, for classifying three classes of sleep stages using Sleep-EDF Expanded dataset. Whereas, the accuracy and Kappa coefficient are 96.57% and 83.05% respectively for five classes of sleep stages using Sleep-EDF Expanded dataset. Our model achieves the best performance in classifying sleep stages when compared with the state-of-the-art techniques.

Patient Independent Interictal Epileptiform Discharge Detection

Epilepsy is a highly prevalent brain condition with many serious complications arising from it. The majority of patients which present to a clinic and undergo electroencephalogram (EEG) monitoring would be unlikely to experience seizures during the examination period, thus the presence of interictal epileptiform discharges (IEDs) become effective markers for the diagnosis of epilepsy. Furthermore, IED shapes and patterns are highly variable across individuals, yet trained experts are still able to identify them through EEG recordings - meaning that commonalities exist across IEDs that an algorithm can be trained on to detect and generalise to the larger population. This research proposes an IED detection system for the binary classification of epilepsy using scalp EEG recordings. The proposed system features an ensemble based deep learning method to boost the performance of a residual convolutional neural network, and a bidirectional long short-term memory network. This is implemented using raw EEG data, sourced from Temple University Hospital's EEG Epilepsy Corpus, and is found to outperform the current state of the art model for IED detection across the same dataset. The achieved accuracy and Area Under Curve (AUC) of 94.92% and 97.45% demonstrates the effectiveness of an ensemble method, and that IED detection can be achieved with high performance using raw scalp EEG data, thus showing promise for the proposed approach in clinical settings.

Human Gesture and Gait Analysis for Autism Detection

Autism diagnosis presents a major challenge due to the vast heterogeneity of the condition and the elusive nature of early detection. Atypical gait and gesture patterns are dominant behavioral characteristics of autism and can provide crucial insights for diagnosis. Furthermore, these data can be collected efficiently in a non-intrusive way, facilitating early intervention to optimize positive outcomes. Existing research mainly focuses on associating facial and eye-gaze features with autism. However, very few studies have investigated movement and gesture patterns which can reveal subtle variations and characteristics that are specific to autism. To address this gap, we present an analysis of gesture and gait activity in videos to identify children with autism and quantify the severity of their condition by regressing autism diagnostic observation schedule scores. Our proposed architecture addresses two key factors: (1) an effective feature representation to manifest irregular gesture patterns and (2) a two-stream co-learning framework to enable a comprehensive understanding of its relation to autism from diverse perspectives without explicitly using additional data modality. Experimental results demonstrate the efficacy of utilizing gesture and gait-activity videos for autism analysis.

Learning Sparse Temporal Video Mapping for Action Quality Assessment in Floor Gymnastics

Athlete performance measurement in sports videos requires modeling long sequences since the entire spatio-temporal progression contributes dominantly to the performance. It is crucial to comprehend local discriminative spatial dependencies and global semantics for accurate evaluation. However, existing benchmark datasets mainly incorporate sports where the performance lasts only a few seconds. Consequently, state-ofthe-art sports quality assessment methods specifically focus on spatial structure. Although they achieve high performance in short-term sports, they are unable to model prolonged video sequences and fail to achieve similar performance in long-term sports. To facilitate such analysis, we introduce a new dataset, coined AGF-Olympics, that incorporates artistic gymnastic floor routines. AFG-Olympics provides highly challenging scenarios with extensive background, viewpoint, and scale variations over an extended sample duration of up to 2 minutes. In addition, we propose a discriminative attention module to map the dense feature space into a sparse representation by disentangling complex associations. Extensive experiments indicate that our proposed module provides an effective way to embed long-range spatial and temporal correlation semantics.

MP-SeizNet: A Multi-Path CNN Bi-LSTM Network for Seizure-Type Classification Using EEG

Seizure type identification is essential for the treatment and management of epileptic patients. However, it is a difficult process known to be time consuming and labor intensive. Automated diagnosis systems, with the advancement of machine learning algorithms, have the potential to accelerate the classification process, alert patients, and support physicians in making quick and accurate decisions. In this paper, we present a novel multi-path seizure-type classification deep learning network (MP-SeizNet), consisting of a convolutional neural network (CNN) and a bidirectional long short-term memory neural network (Bi-LSTM) with an attention mechanism. The objective of this study was to classify specific types of seizures, including complex partial, simple partial, absence, tonic, and tonic-clonic seizures, using only electroencephalogram (EEG) data. The EEG data is fed to our proposed model in two different representations. The CNN was fed with wavelet-based features extracted from the EEG signals, while the Bi-LSTM was fed with raw EEG signals to let our MP-SeizNet jointly learns from different representations of seizure data for more accurate information learning. The proposed MP-SeizNet was evaluated using the largest available EEG epilepsy database, the Temple University Hospital EEG Seizure Corpus, TUSZ v1.5.2. We evaluated our proposed model across different patient data using three-fold cross-validation and across seizure data using five-fold cross-validation, achieving F1 scores of 87.6% and 98.1%, respectively.