Prescribed Generative Adversarial Networks

Generative adversarial networks (GANs) are a powerful approach to unsupervised learning. They have achieved state-of-the-art performance in the image domain. However, GANs are limited in two ways. They often learn distributions with low support---a phenomenon known as mode collapse---and they do not guarantee the existence of a probability density, which makes evaluating generalization using predictive log-likelihood impossible. In this paper, we develop the prescribed GAN (PresGAN) to address these shortcomings. PresGANs add noise to the output of a density network and optimize an entropy-regularized adversarial loss. The added noise renders tractable approximations of the predictive log-likelihood and stabilizes the training procedure. The entropy regularizer encourages PresGANs to capture all the modes of the data distribution. Fitting PresGANs involves computing the intractable gradients of the entropy regularization term; PresGANs sidestep this intractability using unbiased stochastic estimates. We evaluate PresGANs on several datasets and found they mitigate mode collapse and generate samples with high perceptual quality. We further found that PresGANs reduce the gap in performance in terms of predictive log-likelihood between traditional GANs and variational autoencoders (VAEs).

Population Predictive Checks

Bayesian modeling has become a staple for researchers analyzing data. Thanks to recent developments in approximate posterior inference, modern researchers can easily build, use, and revise complicated Bayesian models for large and rich data. These new abilities, however, bring into focus the problem of model assessment. Researchers need tools to diagnose the fitness of their models, to understand where a model falls short, and to guide its revision. In this paper we develop a new method for Bayesian model checking, the population predictive check (Pop-PC). Pop-PCs are built on posterior predictive checks (PPC), a seminal method that checks a model by assessing the posterior predictive distribution on the observed data. Though powerful, PPCs use the data twice---both to calculate the posterior predictive and to evaluate it---which can lead to overconfident assessments. Pop-PCs, in contrast, compare the posterior predictive distribution to the population distribution of the data. This strategy blends Bayesian modeling with frequentist assessment, leading to a robust check that validates the model on its generalization. Of course the population distribution is not usually available; thus we use tools like the bootstrap and cross validation to estimate the Pop-PC. Further, we extend Pop-PCs to hierarchical models. We study Pop-PCs on classical regression and a hierarchical model of text. We show that Pop-PCs are robust to overfitting and can be easily deployed on a broad family of models.

The Dynamic Embedded Topic Model

Topic modeling analyzes documents to learn meaningful patterns of words. Dynamic topic models capture how these patterns vary over time for a set of documents that were collected over a large time span. We develop the dynamic embedded topic model (D-ETM), a generative model of documents that combines dynamic latent Dirichlet allocation (D-LDA) and word embeddings. The D-ETM models each word with a categorical distribution whose parameter is given by the inner product between the word embedding and an embedding representation of its assigned topic at a particular time step. The word embeddings allow the D-ETM to generalize to rare words. The D-ETM learns smooth topic trajectories by defining a random walk prior over the embeddings of the topics. We fit the D-ETM using structured amortized variational inference. On a collection of United Nations debates, we find that the D-ETM learns interpretable topics and outperforms D-LDA in terms of both topic quality and predictive performance.

Topic Modeling in Embedding Spaces

Topic modeling analyzes documents to learn meaningful patterns of words. However, existing topic models fail to learn interpretable topics when working with large and heavy-tailed vocabularies. To this end, we develop the Embedded Topic Model (ETM), a generative model of documents that marries traditional topic models with word embeddings. In particular, it models each word with a categorical distribution whose natural parameter is the inner product between a word embedding and an embedding of its assigned topic. To fit the ETM, we develop an efficient amortized variational inference algorithm. The ETM discovers interpretable topics even with large vocabularies that include rare words and stop words. It outperforms existing document models, such as latent Dirichlet allocation (LDA), in terms of both topic quality and predictive performance.

Bayesian Tensor Filtering: Smooth, Locally-Adaptive Factorization of Functional Matrices

We consider the problem of functional matrix factorization, finding low-dimensional structure in a matrix where every entry is a noisy function evaluated at a set of discrete points. Such problems arise frequently in drug discovery, where biological samples form the rows, candidate drugs form the columns, and entries contain the dose-response curve of a sample treated at different concentrations of a drug. We propose Bayesian Tensor Filtering (BTF), a hierarchical Bayesian model of matrices of functions. BTF captures the smoothness in each individual function while also being locally adaptive to sharp discontinuities. The BTF model is agnostic to the likelihood of the underlying observations, making it flexible enough to handle many different kinds of data. We derive efficient Gibbs samplers for three classes of likelihoods: (i) Gaussian, for which updates are fully conjugate; (ii) Binomial and related likelihoods, for which updates are conditionally conjugate through P{\'o}lya--Gamma augmentation; and (iii) Black-box likelihoods, for which updates are non-conjugate but admit an analytic truncated elliptical slice sampling routine. We compare BTF against a state-of-the-art method for dynamic Poisson matrix factorization, showing BTF better reconstructs held out data in synthetic experiments. Finally, we build a dose-response model around BTF and show on real data from a multi-sample, multi-drug cancer study that BTF outperforms the current standard approach in biology. Code for BTF is available at https://github.com/tansey/functionalmf.

Adapting Neural Networks for the Estimation of Treatment Effects

This paper addresses the use of neural networks for the estimation of treatment effects from observational data. Generally, estimation proceeds in two stages. First, we fit models for the expected outcome and the probability of treatment (propensity score) for each unit. Second, we plug these fitted models into a downstream estimator of the effect. Neural networks are a natural choice for the models in the first step. The question we address is: how can we adapt the design and training of the neural networks used in the first step in order to improve the quality of the final estimate of the treatment effect? We propose two adaptations based on insights from the statistical literature on the estimation of treatment effects. The first is a new architecture, the Dragonnet, that exploits the sufficiency of the propensity score for estimation adjustment. The second is a regularization procedure, targeted regularization, that induces a bias towards models that have non-parametrically optimal asymptotic properties `out-of-the-box`. Studies on benchmark datasets for causal inference show these adaptations outperform existing methods. Code is available at github.com/claudiashi57/dragonnet

Multiple Causes: A Causal Graphical View

Unobserved confounding is a major hurdle for causal inference from observational data. Confounders---the variables that affect both the causes and the outcome---induce spurious non-causal correlations between the two. Wang & Blei (2018) lower this hurdle with "the blessings of multiple causes," where the correlation structure of multiple causes provides indirect evidence for unobserved confounding. They leverage these blessings with an algorithm, called the deconfounder, that uses probabilistic factor models to correct for the confounders. In this paper, we take a causal graphical view of the deconfounder. In a graph that encodes shared confounding, we show how the multiplicity of causes can help identify intervention distributions. We then justify the deconfounder, showing that it makes valid inferences of the intervention. Finally, we expand the class of graphs, and its theory, to those that include other confounders and selection variables. Our results expand the theory in Wang & Blei (2018), justify the deconfounder for causal graphs, and extend the settings where it can be used.

Using Text Embeddings for Causal Inference

We address causal inference with text documents. For example, does adding a theorem to a paper affect its chance of acceptance? Does reporting the gender of a forum post author affect the popularity of the post? We estimate these effects from observational data, where they may be confounded by features of the text such as the subject or writing quality. Although the text suffices for causal adjustment, it is prohibitively high-dimensional. The challenge is to find a low-dimensional text representation that can be used in causal inference. A key insight is that causal adjustment requires only the aspects of text that are predictive of both the treatment and outcome. Our proposed method adapts deep language models to learn low-dimensional embeddings from text that predict these values well; these embeddings suffice for causal adjustment. We establish theoretical properties of this method. We study it empirically on semi-simulated and real data on paper acceptance and forum post popularity. Code is available at https://github.com/blei-lab/causal-text-embeddings.

Equal Opportunity and Affirmative Action via Counterfactual Predictions

Machine learning (ML) can automate decision-making by learning to predict decisions from historical data. However, these predictors may inherit discriminatory policies from past decisions and reproduce unfair decisions. In this paper, we propose two algorithms that adjust fitted ML predictors to make them fair. We focus on two legal notions of fairness: (a) providing equal opportunity (EO) to individuals regardless of sensitive attributes and (b) repairing historical disadvantages through affirmative action (AA). More technically, we produce fair EO and AA predictors by positing a causal model and considering counterfactual decisions. We prove that the resulting predictors are theoretically optimal in predictive performance while satisfying fairness. We evaluate the algorithms, and the trade-offs between accuracy and fairness, on datasets about admissions, income, credit and recidivism.

Variational Bayes under Model Misspecification

Variational Bayes (VB) is a scalable alternative to Markov chain Monte Carlo (MCMC) for Bayesian posterior inference. Though popular, VB comes with few theoretical guarantees, most of which focus on well-specified models. However, models are rarely well-specified in practice. In this work, we study VB under model misspecification. We prove the VB posterior is asymptotically normal and centers at the value that minimizes the Kullback-Leibler (KL) divergence to the true data-generating distribution. Moreover, the VB posterior mean centers at the same value and is also asymptotically normal. These results generalize the variational Bernstein--von Mises theorem [29] to misspecified models. As a consequence of these results, we find that the model misspecification error dominates the variational approximation error in VB posterior predictive distributions. It explains the widely observed phenomenon that VB achieves comparable predictive accuracy with MCMC even though VB uses an approximating family. As illustrations, we study VB under three forms of model misspecification, ranging from model over-/under-dispersion to latent dimensionality misspecification. We conduct two simulation studies that demonstrate the theoretical results.