Medical mT5: An Open-Source Multilingual Text-to-Text LLM for The Medical Domain

Research on language technology for the development of medical applications is currently a hot topic in Natural Language Understanding and Generation. Thus, a number of large language models (LLMs) have recently been adapted to the medical domain, so that they can be used as a tool for mediating in human-AI interaction. While these LLMs display competitive performance on automated medical texts benchmarks, they have been pre-trained and evaluated with a focus on a single language (English mostly). This is particularly true of text-to-text models, which typically require large amounts of domain-specific pre-training data, often not easily accessible for many languages. In this paper, we address these shortcomings by compiling, to the best of our knowledge, the largest multilingual corpus for the medical domain in four languages, namely English, French, Italian and Spanish. This new corpus has been used to train Medical mT5, the first open-source text-to-text multilingual model for the medical domain. Additionally, we present two new evaluation benchmarks for all four languages with the aim of facilitating multilingual research in this domain. A comprehensive evaluation shows that Medical mT5 outperforms both encoders and similarly sized text-to-text models for the Spanish, French, and Italian benchmarks, while being competitive with current state-of-the-art LLMs in English.

Creating a silver standard for patent simplification

Patents are legal documents that aim at protecting inventions on the one hand and at making technical knowledge circulate on the other. Their complex style -- a mix of legal, technical, and extremely vague language -- makes their content hard to access for humans and machines and poses substantial challenges to the information retrieval community. This paper proposes an approach to automatically simplify patent text through rephrasing. Since no in-domain parallel simplification data exist, we propose a method to automatically generate a large-scale silver standard for patent sentences. To obtain candidates, we use a general-domain paraphrasing system; however, the process is error-prone and difficult to control. Thus, we pair it with proper filters and construct a cleaner corpus that can successfully be used to train a simplification system. Human evaluation of the synthetic silver corpus shows that it is considered grammatical, adequate, and contains simple sentences.

Summarization, Simplification, and Generation: The Case of Patents

We survey Natural Language Processing (NLP) approaches to summarizing, simplifying, and generating patents' text. While solving these tasks has important practical applications - given patents' centrality in the R&D process - patents' idiosyncrasies open peculiar challenges to the current NLP state of the art. This survey aims at a) describing patents' characteristics and the questions they raise to the current NLP systems, b) critically presenting previous work and its evolution, and c) drawing attention to directions of research in which further work is needed. To the best of our knowledge, this is the first survey of generative approaches in the patent domain.

Natural Language Processing of Clinical Notes on Chronic Diseases: Systematic Review

Of the 2652 articles considered, 106 met the inclusion criteria. Review of the included papers resulted in identification of 43 chronic diseases, which were then further classified into 10 disease categories using ICD-10. The majority of studies focused on diseases of the circulatory system (n=38) while endocrine and metabolic diseases were fewest (n=14). This was due to the structure of clinical records related to metabolic diseases, which typically contain much more structured data, compared with medical records for diseases of the circulatory system, which focus more on unstructured data and consequently have seen a stronger focus of NLP. The review has shown that there is a significant increase in the use of machine learning methods compared to rule-based approaches; however, deep learning methods remain emergent (n=3). Consequently, the majority of works focus on classification of disease phenotype with only a handful of papers addressing extraction of comorbidities from the free text or integration of clinical notes with structured data. There is a notable use of relatively simple methods, such as shallow classifiers (or combination with rule-based methods), due to the interpretability of predictions, which still represents a significant issue for more complex methods. Finally, scarcity of publicly available data may also have contributed to insufficient development of more advanced methods, such as extraction of word embeddings from clinical notes. Further efforts are still required to improve (1) progression of clinical NLP methods from extraction toward understanding; (2) recognition of relations among entities rather than entities in isolation; (3) temporal extraction to understand past, current, and future clinical events; (4) exploitation of alternative sources of clinical knowledge; and (5) availability of large-scale, de-identified clinical corpora.