Recent advances in test-time adaptation (TTA) for Vision-Language Models (VLMs) have garnered increasing attention, particularly through the use of multiple augmented views of a single image to boost zero-shot generalization. Unfortunately, existing methods fail to strike a satisfactory balance between performance and efficiency, either due to excessive overhead of tuning text prompts or unstable benefits from handcrafted, training-free visual feature enhancement. In this paper, we present Global-Spatial Bias Learner (GS-Bias), an efficient and effective TTA paradigm that incorporates two learnable biases during TTA, unfolded as the global bias and spatial bias. Particularly, the global bias captures the global semantic features of a test image by learning consistency across augmented views, while spatial bias learns the semantic coherence between regions in the image's spatial visual representation. It is worth highlighting that these two sets of biases are directly added to the logits outputed by the pretrained VLMs, which circumvent the full backpropagation through VLM that hinders the efficiency of existing TTA methods. This endows GS-Bias with extremely high efficiency while achieving state-of-the-art performance on 15 benchmark datasets. For example, it achieves a 2.23% improvement over TPT in cross-dataset generalization and a 2.72% improvement in domain generalization, while requiring only 6.5% of TPT's memory usage on ImageNet.