MindSimulator: Exploring Brain Concept Localization via Synthetic FMRI

Concept-selective regions within the human cerebral cortex exhibit significant activation in response to specific visual stimuli associated with particular concepts. Precisely localizing these regions stands as a crucial long-term goal in neuroscience to grasp essential brain functions and mechanisms. Conventional experiment-driven approaches hinge on manually constructed visual stimulus collections and corresponding brain activity recordings, constraining the support and coverage of concept localization. Additionally, these stimuli often consist of concept objects in unnatural contexts and are potentially biased by subjective preferences, thus prompting concerns about the validity and generalizability of the identified regions. To address these limitations, we propose a data-driven exploration approach. By synthesizing extensive brain activity recordings, we statistically localize various concept-selective regions. Our proposed MindSimulator leverages advanced generative technologies to learn the probability distribution of brain activity conditioned on concept-oriented visual stimuli. This enables the creation of simulated brain recordings that reflect real neural response patterns. Using the synthetic recordings, we successfully localize several well-studied concept-selective regions and validate them against empirical findings, achieving promising prediction accuracy. The feasibility opens avenues for exploring novel concept-selective regions and provides prior hypotheses for future neuroscience research.

HyDiscGAN: A Hybrid Distributed cGAN for Audio-Visual Privacy Preservation in Multimodal Sentiment Analysis

Multimodal Sentiment Analysis (MSA) aims to identify speakers' sentiment tendencies in multimodal video content, raising serious concerns about privacy risks associated with multimodal data, such as voiceprints and facial images. Recent distributed collaborative learning has been verified as an effective paradigm for privacy preservation in multimodal tasks. However, they often overlook the privacy distinctions among different modalities, struggling to strike a balance between performance and privacy preservation. Consequently, it poses an intriguing question of maximizing multimodal utilization to improve performance while simultaneously protecting necessary modalities. This paper forms the first attempt at modality-specified (i.e., audio and visual) privacy preservation in MSA tasks. We propose a novel Hybrid Distributed cross-modality cGAN framework (HyDiscGAN), which learns multimodality alignment to generate fake audio and visual features conditioned on shareable de-identified textual data. The objective is to leverage the fake features to approximate real audio and visual content to guarantee privacy preservation while effectively enhancing performance. Extensive experiments show that compared with the state-of-the-art MSA model, HyDiscGAN can achieve superior or competitive performance while preserving privacy.