MedCLIPSeg: Probabilistic Vision-Language Adaptation for Data-Efficient and Generalizable Medical Image Segmentation

Medical image segmentation remains challenging due to limited annotations for training, ambiguous anatomical features, and domain shifts. While vision-language models such as CLIP offer strong cross-modal representations, their potential for dense, text-guided medical image segmentation remains underexplored. We present MedCLIPSeg, a novel framework that adapts CLIP for robust, data-efficient, and uncertainty-aware medical image segmentation. Our approach leverages patch-level CLIP embeddings through probabilistic cross-modal attention, enabling bidirectional interaction between image and text tokens and explicit modeling of predictive uncertainty. Together with a soft patch-level contrastive loss that encourages more nuanced semantic learning across diverse textual prompts, MedCLIPSeg effectively improves data efficiency and domain generalizability. Extensive experiments across 16 datasets spanning five imaging modalities and six organs demonstrate that MedCLIPSeg outperforms prior methods in accuracy, efficiency, and robustness, while providing interpretable uncertainty maps that highlight local reliability of segmentation results. This work demonstrates the potential of probabilistic vision-language modeling for text-driven medical image segmentation.

DisastQA: A Comprehensive Benchmark for Evaluating Question Answering in Disaster Management

Accurate question answering (QA) in disaster management requires reasoning over uncertain and conflicting information, a setting poorly captured by existing benchmarks built on clean evidence. We introduce DisastQA, a large-scale benchmark of 3,000 rigorously verified questions (2,000 multiple-choice and 1,000 open-ended) spanning eight disaster types. The benchmark is constructed via a human-LLM collaboration pipeline with stratified sampling to ensure balanced coverage. Models are evaluated under varying evidence conditions, from closed-book to noisy evidence integration, enabling separation of internal knowledge from reasoning under imperfect information. For open-ended QA, we propose a human-verified keypoint-based evaluation protocol emphasizing factual completeness over verbosity. Experiments with 20 models reveal substantial divergences from general-purpose leaderboards such as MMLU-Pro. While recent open-weight models approach proprietary systems in clean settings, performance degrades sharply under realistic noise, exposing critical reliability gaps for disaster response. All code, data, and evaluation resources are available at https://github.com/TamuChen18/DisastQA_open.

Singular Value Few-shot Adaptation of Vision-Language Models

Vision-language models (VLMs) like CLIP have shown impressive zero-shot and few-shot learning capabilities across diverse applications. However, adapting these models to new fine-grained domains remains difficult due to reliance on prompt engineering and the high cost of full model fine-tuning. Existing adaptation approaches rely on augmented components, such as prompt tokens and adapter modules, which could limit adaptation quality, destabilize the model, and compromise the rich knowledge learned during pretraining. In this work, we present \textbf{CLIP-SVD}, a novel \textit{multi-modal} and \textit{parameter-efficient} adaptation technique that leverages Singular Value Decomposition (SVD) to modify the internal parameter space of CLIP without injecting additional modules. Specifically, we fine-tune only the singular values of the CLIP parameter matrices to rescale the basis vectors for domain adaptation while retaining the pretrained model. This design enables enhanced adaptation performance using only \textbf{0.04\%} of the model's total parameters and better preservation of its generalization ability. CLIP-SVD achieves state-of-the-art classification results on 11 natural and 10 biomedical datasets, outperforming previous methods in both accuracy and generalization under few-shot settings. Additionally, we leverage a natural language-based approach to analyze the effectiveness and dynamics of the CLIP adaptation to allow interpretability of CLIP-SVD. The code is publicly available at https://github.com/HealthX-Lab/CLIP-SVD.

DINOMotion: advanced robust tissue motion tracking with DINOv2 in 2D-Cine MRI-guided radiotherapy

Accurate tissue motion tracking is critical to ensure treatment outcome and safety in 2D-Cine MRI-guided radiotherapy. This is typically achieved by registration of sequential images, but existing methods often face challenges with large misalignments and lack of interpretability. In this paper, we introduce DINOMotion, a novel deep learning framework based on DINOv2 with Low-Rank Adaptation (LoRA) layers for robust, efficient, and interpretable motion tracking. DINOMotion automatically detects corresponding landmarks to derive optimal image registration, enhancing interpretability by providing explicit visual correspondences between sequential images. The integration of LoRA layers reduces trainable parameters, improving training efficiency, while DINOv2's powerful feature representations offer robustness against large misalignments. Unlike iterative optimization-based methods, DINOMotion directly computes image registration at test time. Our experiments on volunteer and patient datasets demonstrate its effectiveness in estimating both linear and nonlinear transformations, achieving Dice scores of 92.07% for the kidney, 90.90% for the liver, and 95.23% for the lung, with corresponding Hausdorff distances of 5.47 mm, 8.31 mm, and 6.72 mm, respectively. DINOMotion processes each scan in approximately 30ms and consistently outperforms state-of-the-art methods, particularly in handling large misalignments. These results highlight its potential as a robust and interpretable solution for real-time motion tracking in 2D-Cine MRI-guided radiotherapy.

Weakly Supervised Intracranial Aneurysm Detection and Segmentation in MR angiography via Multi-task UNet with Vesselness Prior

Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform accurate and efficient detection and morphological analyses, which are critical in the clinical care of the disorder. Furthermore, the lack of large public datasets with voxel-wise expert annotations pose challenges for developing deep learning algorithms to address the issues. Therefore, we proposed a novel weakly supervised 3D multi-task UNet that integrates vesselness priors to jointly perform aneurysm detection and segmentation in time-of-flight MR angiography (TOF-MRA). Specifically, to robustly guide IA detection and segmentation, we employ the popular Frangi's vesselness filter to derive soft cerebrovascular priors for both network input and an attention block to conduct segmentation from the decoder and detection from an auxiliary branch. We train our model on the Lausanne dataset with coarse ground truth segmentation, and evaluate it on the test set with refined labels from the same database. To further assess our model's generalizability, we also validate it externally on the ADAM dataset. Our results demonstrate the superior performance of the proposed technique over the SOTA techniques for aneurysm segmentation (Dice = 0.614, 95%HD =1.38mm) and detection (false positive rate = 1.47, sensitivity = 92.9%).

TextSAM-EUS: Text Prompt Learning for SAM to Accurately Segment Pancreatic Tumor in Endoscopic Ultrasound

Pancreatic cancer carries a poor prognosis and relies on endoscopic ultrasound (EUS) for targeted biopsy and radiotherapy. However, the speckle noise, low contrast, and unintuitive appearance of EUS make segmentation of pancreatic tumors with fully supervised deep learning (DL) models both error-prone and dependent on large, expert-curated annotation datasets. To address these challenges, we present TextSAM-EUS, a novel, lightweight, text-driven adaptation of the Segment Anything Model (SAM) that requires no manual geometric prompts at inference. Our approach leverages text prompt learning (context optimization) through the BiomedCLIP text encoder in conjunction with a LoRA-based adaptation of SAM's architecture to enable automatic pancreatic tumor segmentation in EUS, tuning only 0.86% of the total parameters. On the public Endoscopic Ultrasound Database of the Pancreas, TextSAM-EUS with automatic prompts attains 82.69% Dice and 85.28% normalized surface distance (NSD), and with manual geometric prompts reaches 83.10% Dice and 85.70% NSD, outperforming both existing state-of-the-art (SOTA) supervised DL models and foundation models (e.g., SAM and its variants). As the first attempt to incorporate prompt learning in SAM-based medical image segmentation, TextSAM-EUS offers a practical option for efficient and robust automatic EUS segmentation. Our code will be publicly available upon acceptance.

SS-DC: Spatial-Spectral Decoupling and Coupling Across Visible-Infrared Gap for Domain Adaptive Object Detection

Unsupervised domain adaptive object detection (UDAOD) from the visible domain to the infrared (RGB-IR) domain is challenging. Existing methods regard the RGB domain as a unified domain and neglect the multiple subdomains within it, such as daytime, nighttime, and foggy scenes. We argue that decoupling the domain-invariant (DI) and domain-specific (DS) features across these multiple subdomains is beneficial for RGB-IR domain adaptation. To this end, this paper proposes a new SS-DC framework based on a decoupling-coupling strategy. In terms of decoupling, we design a Spectral Adaptive Idempotent Decoupling (SAID) module in the aspect of spectral decomposition. Due to the style and content information being highly embedded in different frequency bands, this module can decouple DI and DS components more accurately and interpretably. A novel filter bank-based spectral processing paradigm and a self-distillation-driven decoupling loss are proposed to improve the spectral domain decoupling. In terms of coupling, a new spatial-spectral coupling method is proposed, which realizes joint coupling through spatial and spectral DI feature pyramids. Meanwhile, this paper introduces DS from decoupling to reduce the domain bias. Extensive experiments demonstrate that our method can significantly improve the baseline performance and outperform existing UDAOD methods on multiple RGB-IR datasets, including a new experimental protocol proposed in this paper based on the FLIR-ADAS dataset.

DisastIR: A Comprehensive Information Retrieval Benchmark for Disaster Management

Effective disaster management requires timely access to accurate and contextually relevant information. Existing Information Retrieval (IR) benchmarks, however, focus primarily on general or specialized domains, such as medicine or finance, neglecting the unique linguistic complexity and diverse information needs encountered in disaster management scenarios. To bridge this gap, we introduce DisastIR, the first comprehensive IR evaluation benchmark specifically tailored for disaster management. DisastIR comprises 9,600 diverse user queries and more than 1.3 million labeled query-passage pairs, covering 48 distinct retrieval tasks derived from six search intents and eight general disaster categories that include 301 specific event types. Our evaluations of 30 state-of-the-art retrieval models demonstrate significant performance variances across tasks, with no single model excelling universally. Furthermore, comparative analyses reveal significant performance gaps between general-domain and disaster management-specific tasks, highlighting the necessity of disaster management-specific benchmarks for guiding IR model selection to support effective decision-making in disaster management scenarios. All source codes and DisastIR are available at https://github.com/KaiYin97/Disaster_IR.

Towards user-centered interactive medical image segmentation in VR with an assistive AI agent

Crucial in disease analysis and surgical planning, manual segmentation of volumetric medical scans (e.g. MRI, CT) is laborious, error-prone, and challenging to master, while fully automatic algorithms can benefit from user feedback. Therefore, with the complementary power of the latest radiological AI foundation models and virtual reality (VR)'s intuitive data interaction, we propose SAMIRA, a novel conversational AI agent that assists users with localizing, segmenting, and visualizing 3D medical concepts in VR. Through speech-based interaction, the agent helps users understand radiological features, locate clinical targets, and generate segmentation masks that can be refined with just a few point prompts. The system also supports true-to-scale 3D visualization of segmented pathology to enhance patient-specific anatomical understanding. Furthermore, to determine the optimal interaction paradigm under near-far attention-switching for refining segmentation masks in an immersive, human-in-the-loop workflow, we compare VR controller pointing, head pointing, and eye tracking as input modes. With a user study, evaluations demonstrated a high usability score (SUS=90.0 $\pm$ 9.0), low overall task load, as well as strong support for the proposed VR system's guidance, training potential, and integration of AI in radiological segmentation tasks.

DamageCAT: A Deep Learning Transformer Framework for Typology-Based Post-Disaster Building Damage Categorization

Natural disasters increasingly threaten communities worldwide, creating an urgent need for rapid, reliable building damage assessment to guide emergency response and recovery efforts. Current methods typically classify damage in binary (damaged/undamaged) or ordinal severity terms, limiting their practical utility. In fact, the determination of damage typology is crucial for response and recovery efforts. To address this important gap, this paper introduces DamageCAT, a novel framework that provides typology-based categorical damage descriptions rather than simple severity ratings. Accordingly, this study presents two key contributions: (1) the BD-TypoSAT dataset containing satellite image triplets (pre-disaster, post-disaster, and damage masks) from Hurricane Ida with four damage categories (partial roof damage, total roof damage, partial structural collapse, and total structural collapse), and (2) a hierarchical U-Net-based transformer architecture that effectively processes pre-post disaster image pairs to identify and categorize building damage. Despite significant class imbalances in the training data, our model achieved robust performance with overall metrics of 0.7921 Intersection over Union (IoU) and 0.8835 F1 scores across all categories. The model's capability to recognize intricate damage typology in less common categories is especially remarkable. The DamageCAT framework advances automated damage assessment by providing actionable, typological information that better supports disaster response decision-making and resource allocation compared to traditional severity-based approaches.