D-NOVA: In-Storage Retrieval Accelerator via Dual-Bound 3D NAND-Optimized Similarity Search with Vector Adaptation

Retrieval-Augmented Generation (RAG) enhances the factual grounding of large language model (LLM) inference by retrieving relevant information from external knowledge bases. However, its dense vector retrieval introduces significant latency and energy overhead, becoming the primary performance bottleneck. Although recent in-storage accelerators aim to reduce data movement, they still rely on host or embedded processors outside the memory, where nearly 70% of the total retrieval time is spent. As a result, they cannot fully overcome the bandwidth limitations, leading to yet another memory bottleneck. To tackle these limitations, we present D-NOVA, a hardware-software co-designed in-storage retrieval accelerator. D-NOVA executes an inverted file (IVF)-based hierarchical retrieval pipeline by deeply embedding the search functionality directly into the NAND memory array. This is achieved by incorporating a new distance metric, Dual-Bound Tight Similarity Sensing (DTS), which is specifically tailored for searching within the NAND string. In addition, we introduce a lightweight contrastive adapter that maps embedding vectors into a DTS-friendly domain, recovering near-software recall while improving performance and energy efficiency. D-NOVA is up to 41.7x faster and 71x more energy-efficient than a CPU baseline, and achieves 12.13x higher throughput while being up to 1.26x more energy-efficient than state-of-the-art in-storage RAG accelerators, demonstrating the potential of fully in-storage vector search for scalable RAG acceleration.

SpecHD: Hyperdimensional Computing Framework for FPGA-based Mass Spectrometry Clustering

Mass spectrometry-based proteomics is a key enabler for personalized healthcare, providing a deep dive into the complex protein compositions of biological systems. This technology has vast applications in biotechnology and biomedicine but faces significant computational bottlenecks. Current methodologies often require multiple hours or even days to process extensive datasets, particularly in the domain of spectral clustering. To tackle these inefficiencies, we introduce SpecHD, a hyperdimensional computing (HDC) framework supplemented by an FPGA-accelerated architecture with integrated near-storage preprocessing. Utilizing streamlined binary operations in an HDC environment, SpecHD capitalizes on the low-latency and parallel capabilities of FPGAs. This approach markedly improves clustering speed and efficiency, serving as a catalyst for real-time, high-throughput data analysis in future healthcare applications. Our evaluations demonstrate that SpecHD not only maintains but often surpasses existing clustering quality metrics while drastically cutting computational time. Specifically, it can cluster a large-scale human proteome dataset-comprising 25 million MS/MS spectra and 131 GB of MS data-in just 5 minutes. With energy efficiency exceeding 31x and a speedup factor that spans a range of 6x to 54x over existing state of-the-art solutions, SpecHD emerges as a promising solution for the rapid analysis of mass spectrometry data with great implications for personalized healthcare.