DiffSOS: Acoustic Conditional Diffusion Model for Speed-of-Sound Reconstruction in Ultrasound Computed Tomography

Accurate Speed-of-Sound (SoS) reconstruction from acoustic waveforms is a cornerstone of ultrasound computed tomography (USCT), enabling quantitative velocity mapping that reveals subtle anatomical details and pathological variations often invisible in conventional imaging. However, practical utility is hindered by the limitations of existing algorithms; traditional Full Waveform Inversion (FWI) is computationally intensive, while current deep learning approaches tend to produce oversmoothed results lacking fine details. We propose DiffSOS, a conditional diffusion model that directly maps acoustic waveforms to SoS maps. Our framework employs a specialized acoustic ControlNet to strictly ground the denoising process in physical wave measurements. To ensure structural consistency, we optimize a hybrid loss function that integrates noise prediction, spatial reconstruction, and noise frequency content. To accelerate inference, we employ stochastic Denoising Diffusion Implicit Model (DDIM) sampling, achieving near real-time reconstruction with only 10 steps. Crucially, we exploit the stochastic generative nature of our framework to estimate pixel-wise uncertainty, providing a measure of reliability that is often absent in deterministic approaches. Evaluated on the OpenPros USCT benchmark, DiffSOS significantly outperforms state-of-the-art networks, achieving an average Multi-scale Structural Similarity of 0.957. Our approach provides high-fidelity SoS maps with a principled measure of confidence, facilitating safer and faster clinical interpretation.

IRSDE-Despeckle: A Physics-Grounded Diffusion Model for Generalizable Ultrasound Despeckling

Ultrasound imaging is widely used for real-time, noninvasive diagnosis, but speckle and related artifacts reduce image quality and can hinder interpretation. We present a diffusion-based ultrasound despeckling method built on the Image Restoration Stochastic Differential Equations framework. To enable supervised training, we curate large paired datasets by simulating ultrasound images from speckle-free magnetic resonance images using the Matlab UltraSound Toolbox. The proposed model reconstructs speckle-suppressed images while preserving anatomically meaningful edges and contrast. On a held-out simulated test set, our approach consistently outperforms classical filters and recent learning-based despeckling baselines. We quantify prediction uncertainty via cross-model variance and show that higher uncertainty correlates with higher reconstruction error, providing a practical indicator of difficult or failure-prone regions. Finally, we evaluate sensitivity to simulation probe settings and observe domain shift, motivating diversified training and adaptation for robust clinical deployment.

Gait Design of a Novel Arboreal Concertina Locomotion for Snake-like Robots

In this paper, we propose a novel strategy for a snake robot to move straight up a cylindrical surface. Prior works on pole-climbing for a snake robot mainly utilized a rolling helix gait, and although proven to be efficient, it does not reassemble movements made by a natural snake. We take inspiration from nature and seek to imitate the Arboreal Concertina Locomotion (ACL) from real-life serpents. In order to represent the 3D curves that make up the key motion patterns of ACL, we establish a set of parametric equations that identify periodic functions, which produce a sequence of backbone curves. We then build up the gait equation using the curvature integration method, and finally, we propose a simple motion estimation strategy using virtual chassis and non-slip model assumptions. We present experimental results using a 20-DOF snake robot traversing outside of a straight pipe.