Multi-Class Brain Tumor Classification Using Advanced Deep Learning Models: A Comparative Study

Despite recent advancements in deep learning, accurately classifying brain tumors from MRI images continues to pose challenges. In this research, we present a comprehensive evaluation of five different convolutional neural networks (CNN) architectures, including a customized baseline model and four pre-trained models - for use in classifying multi-class brain tumors using a clinically-sourced dataset of approximately 10,000 MRI images. We have utilized five different architectures; VGG16, VGG19, DenseNet121, and EfficientNetB0, which were all tested and trained within an identical experimental framework. Performance was measured by both overall accuracy and tumor-wise recall as a means to measure the clinically-relevant performance of each architecture. We found that EfficientNetB0 had the best overall classification accuracy at 95%, when compared to the other architectures tested; specifically VGG16 (94.37%), VGG19 (92.29%), DenseNet121 (90.91%) and the customized CNN (78.00%). An especially important finding of our research was the considerable improvement in detecting meningiomas; specifically, while simple CNNs could detect meningiomas with a recall rate of approximately 20%, EfficientNetB0 was able to detect meningiomas with a recall rate of 89%. Meningiomas are often difficult to detect because they can appear very subtly on MRI images. Additionally, an interesting finding was that the deeper VGG19 performed worse than the shallower VGG16. This indicates that in many cases the architectural efficiency of a CNN model may be more important than its depth when working with medical images. Overall, EfficientNetB0 appears to provide the optimal trade-off between classification accuracy, number of parameters used in the model and clinically meaningful performance.

PEFT-MedSAM: Efficient Fine-Tuning of Medical Foundation Models for Explainable Skin Lesion Segmentation

Automated segmentation of skin lesions using deep learning models for dermoscopic images can be very helpful in finding melanomas earlier than they would normally be detected. However, most deep learning methods available do not perform well. The aim of this paper is to present a parameter-efficient fine-tuning method called PEFT-MedSAM for adapting the Medical Segment Anything Model (MedSAM) to automatically segment dermoscopic skin lesions. The PEFT-MedSAM method uses only the lightweight mask decoder for training the model while keeping the pre-trained image encoder and prompt encoder frozen. The experiments performed on the ISIC 2018 benchmark dataset shows that PEFT-MedSAM obtains a dice coefficient of .9411 and an intersection over union value of .8918 when compared to both a fully trained U-Net baseline (.8715 dice coefficient) and zero-shot MedSAM inference (.8997 dice coefficient). The external validation of the model using PH2 dataset shows .9467 dice coefficient with +/- .0310 standard deviation. Supportive evidence for these claims include a p-value less than .0001 for Wilcoxon signed rank tests comparing the two datasets and bootstrap-estimated 95% confidence intervals of [.9364,.9447] that represent the estimated range of possible values for the average dice coefficient obtained by repeating the test. To increase clinical trustworthiness, we used Grad-CAM explainability along with a pointing game based evaluation methodology to evaluate the CNN baseline model on the validation set. The results showed that we had an accuracy rate of 98.27% on the validation set of 519 images and confirmed that the model classified regions containing skin lesions.

Ciphera: A Decentralised Biometric Identity Framework

Centralised biometric identity systems expose users to single points of failure, opaque verification processes, and irreversible biometric compromise. Decentralised Identifiers (DIDs) and Verifiable Credentials (VCs) offer stronger privacy guarantees, yet their integration with biometric authentication and distributed verification remains insufficiently explored. This paper presents Ciphera, a decentralised biometric identity framework combining privacy-preserving facial recognition, multi-node verification, IPFS-based credential metadata storage, and blockchain-anchored revocation. Evaluated across functional, performance, security, and distributed consistency dimensions, Ciphera achieved an 81% functional success rate, with stable enrolment and authentication but measurable revocation propagation delays and occasional audit-log inconsistencies. Performance testing demonstrated sub-second p95 verification latency of approximately 820ms under concurrent multi-node conditions. Security analysis confirmed strong confidentiality and integrity guarantees, though incomplete liveness detection leaves susceptibility to deepfake and replay attacks. The results demonstrate the feasibility of decentralised biometric identity while identifying key engineering challenges for production-grade deployment.

Comparative Evaluation of Deep Learning Models for Fake Image Detection

The growing sophistication of GAN-based image manipulation presents significant challenges for digital forensics. This study compares the performance of four pretrained CNN architectures including VGG16, ResNet50, EfficientNetB0, and XceptionNet for fake image detection using a unified preprocessing and training pipeline. A dataset of real and manipulated images was processed through resizing, normalization, and augmentation to address class imbalance and improve generalization. Models were evaluated using Accuracy, Precision, Recall, F1-score, and ROC-AUC. VGG16 achieved the highest accuracy at 91%, with XceptionNet, ResNet50, and EfficientNetB0 each reaching 90%. EfficientNetB0 showed stronger sensitivity to fake images but reduced reliability on real samples, reflecting imbalance-driven bias. Limitations include dataset imbalance, overfitting, and limited interpretability, which affect cross-domain robustness. The study provides a reproducible baseline and underscores the need for balanced datasets, advanced augmentation, and fairness-aware training to develop reliable fake image detection systems.