Federated Learning Enables Big Data for Rare Cancer Boundary Detection

Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally sharing ample, and importantly diverse, data from multiple sites. However, such centralization is challenging to scale (or even not feasible) due to various limitations. Federated ML (FL) provides an alternative to train accurate and generalizable ML models, by only sharing numerical model updates. Here we present findings from the largest FL study to-date, involving data from 71 healthcare institutions across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, utilizing the largest dataset of such patients ever used in the literature (25,256 MRI scans from 6,314 patients). We demonstrate a 33% improvement over a publicly trained model to delineate the surgically targetable tumor, and 23% improvement over the tumor's entire extent. We anticipate our study to: 1) enable more studies in healthcare informed by large and diverse data, ensuring meaningful results for rare diseases and underrepresented populations, 2) facilitate further quantitative analyses for glioblastoma via performance optimization of our consensus model for eventual public release, and 3) demonstrate the effectiveness of FL at such scale and task complexity as a paradigm shift for multi-site collaborations, alleviating the need for data sharing.

A Unified Deep Framework for Joint 3D Pose Estimation and Action Recognition from a Single RGB Camera

We present a deep learning-based multitask framework for joint 3D human pose estimation and action recognition from RGB video sequences. Our approach proceeds along two stages. In the first, we run a real-time 2D pose detector to determine the precise pixel location of important keypoints of the body. A two-stream neural network is then designed and trained to map detected 2D keypoints into 3D poses. In the second, we deploy the Efficient Neural Architecture Search (ENAS) algorithm to find an optimal network architecture that is used for modeling the spatio-temporal evolution of the estimated 3D poses via an image-based intermediate representation and performing action recognition. Experiments on Human3.6M, MSR Action3D and SBU Kinect Interaction datasets verify the effectiveness of the proposed method on the targeted tasks. Moreover, we show that our method requires a low computational budget for training and inference.

A Deep Learning Approach for Real-Time 3D Human Action Recognition from Skeletal Data

We present a new deep learning approach for real-time 3D human action recognition from skeletal data and apply it to develop a vision-based intelligent surveillance system. Given a skeleton sequence, we propose to encode skeleton poses and their motions into a single RGB image. An Adaptive Histogram Equalization (AHE) algorithm is then applied on the color images to enhance their local patterns and generate more discriminative features. For learning and classification tasks, we design Deep Neural Networks based on the Densely Connected Convolutional Architecture (DenseNet) to extract features from enhanced-color images and classify them into classes. Experimental results on two challenging datasets show that the proposed method reaches state-of-the-art accuracy, whilst requiring low computational time for training and inference. This paper also introduces CEMEST, a new RGB-D dataset depicting passenger behaviors in public transport. It consists of 203 untrimmed real-world surveillance videos of realistic normal and anomalous events. We achieve promising results on real conditions of this dataset with the support of data augmentation and transfer learning techniques. This enables the construction of real-world applications based on deep learning for enhancing monitoring and security in public transport.