Abstract:Accurate sleep stage classification is essential for diagnosing sleep disorders, particularly in aging populations. While traditional polysomnography (PSG) relies on electroencephalography (EEG) as the gold standard, its complexity and need for specialized equipment make home-based sleep monitoring challenging. To address this limitation, we investigate the use of electrooculography (EOG) and pressure-sensitive mats (PSM) as less obtrusive alternatives for five-stage sleep-wake classification. This study introduces a novel approach that leverages ImageBind, a multimodal embedding deep learning model, to integrate PSM data with dual-channel EOG signals for sleep stage classification. Our method is the first reported approach that fuses PSM and EOG data for sleep stage classification with ImageBind. Our results demonstrate that fine-tuning ImageBind significantly improves classification accuracy, outperforming existing models based on single-channel EOG (DeepSleepNet), exclusively PSM data (ViViT), and other multimodal deep learning approaches (MBT). Notably, the model also achieved strong performance without fine-tuning, highlighting its adaptability to specific tasks with limited labeled data, making it particularly advantageous for medical applications. We evaluated our method using 85 nights of patient recordings from a sleep clinic. Our findings suggest that pre-trained multimodal embedding models, even those originally developed for non-medical domains, can be effectively adapted for sleep staging, with accuracies approaching systems that require complex EEG data.
Abstract:Bed-based pressure-sensitive mats (PSMs) offer a non-intrusive way of monitoring patients during sleep. We focus on four-way sleep position classification using data collected from a PSM placed under a mattress in a sleep clinic. Sleep positions can affect sleep quality and the prevalence of sleep disorders, such as apnea. Measurements were performed on patients with suspected sleep disorders referred for assessments at a sleep clinic. Training deep learning models can be challenging in clinical settings due to the need for large amounts of labeled data. To overcome the shortage of labeled training data, we utilize transfer learning to adapt pre-trained deep learning models to accurately estimate sleep positions from a low-resolution PSM dataset collected in a polysomnography sleep lab. Our approach leverages Vision Transformer models pre-trained on ImageNet using masked autoencoding (ViTMAE) and a pre-trained model for human pose estimation (ViTPose). These approaches outperform previous work from PSM-based sleep pose classification using deep learning (TCN) as well as traditional machine learning models (SVM, XGBoost, Random Forest) that use engineered features. We evaluate the performance of sleep position classification from 112 nights of patient recordings and validate it on a higher resolution 13-patient dataset. Despite the challenges of differentiating between sleep positions from low-resolution PSM data, our approach shows promise for real-world deployment in clinical settings
Abstract:Breast cancer is the most common cancer in women worldwide. The most common screening technology is mammography. To reduce the cost and workload of radiologists, we propose a computer aided detection approach for classifying and localizing calcifications and masses in mammogram images. To improve on conventional approaches, we apply deep convolutional neural networks (CNN) for automatic feature learning and classifier building. In computer-aided mammography, deep CNN classifiers cannot be trained directly on full mammogram images because of the loss of image details from resizing at input layers. Instead, our classifiers are trained on labelled image patches and then adapted to work on full mammogram images for localizing the abnormalities. State-of-the-art deep convolutional neural networks are compared on their performance of classifying the abnormalities. Experimental results indicate that VGGNet receives the best overall accuracy at 92.53\% in classifications. For localizing abnormalities, ResNet is selected for computing class activation maps because it is ready to be deployed without structural change or further training. Our approach demonstrates that deep convolutional neural network classifiers have remarkable localization capabilities despite no supervision on the location of abnormalities is provided.