Safeguarding Patient Trust in the Age of AI: Tackling Health Misinformation with Explainable AI

AI-generated health misinformation poses unprecedented threats to patient safety and healthcare system trust globally. This white paper presents an explainable AI framework developed through the EPSRC INDICATE project to combat medical misinformation while enhancing evidence-based healthcare delivery. Our systematic review of 17 studies reveals the urgent need for transparent AI systems in healthcare. The proposed solution demonstrates 95% recall in clinical evidence retrieval and integrates novel trustworthiness classifiers achieving 76% F1 score in detecting biomedical misinformation. Results show that explainable AI can transform traditional 6-month expert review processes into real-time, automated evidence synthesis while maintaining clinical rigor. This approach offers a critical intervention to preserve healthcare integrity in the AI era.

An Automated LLM-based Pipeline for Asset-Level Database Creation to Assess Deforestation Impact

The European Union Deforestation Regulation (EUDR) requires companies to prove their products do not contribute to deforestation, creating a critical demand for precise, asset-level environmental impact data. Current databases lack the necessary detail, relying heavily on broad financial metrics and manual data collection, which limits regulatory compliance and accurate environmental modeling. This study presents an automated, end-to-end data extraction pipeline that uses LLMs to create, clean, and validate structured databases, specifically targeting sectors with a high risk of deforestation. The pipeline introduces Instructional, Role-Based, Zero-Shot Chain-of-Thought (IRZ-CoT) prompting to enhance data extraction accuracy and a Retrieval-Augmented Validation (RAV) process that integrates real-time web searches for improved data reliability. Applied to SEC EDGAR filings in the Mining, Oil & Gas, and Utilities sectors, the pipeline demonstrates significant improvements over traditional zero-shot prompting approaches, particularly in extraction accuracy and validation coverage. This work advances NLP-driven automation for regulatory compliance, CSR (Corporate Social Responsibility), and ESG, with broad sectoral applicability.

Pub-Guard-LLM: Detecting Fraudulent Biomedical Articles with Reliable Explanations

A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first large language model-based system tailored to fraud detection of biomedical scientific articles. We provide three application modes for deploying Pub-Guard-LLM: vanilla reasoning, retrieval-augmented generation, and multi-agent debate. Each mode allows for textual explanations of predictions. To assess the performance of our system, we introduce an open-source benchmark, PubMed Retraction, comprising over 11K real-world biomedical articles, including metadata and retraction labels. We show that, across all modes, Pub-Guard-LLM consistently surpasses the performance of various baselines and provides more reliable explanations, namely explanations which are deemed more relevant and coherent than those generated by the baselines when evaluated by multiple assessment methods. By enhancing both detection performance and explainability in scientific fraud detection, Pub-Guard-LLM contributes to safeguarding research integrity with a novel, effective, open-source tool.

Collective Knowledge Graph Completion with Mutual Knowledge Distillation

Knowledge graph completion (KGC), the task of predicting missing information based on the existing relational data inside a knowledge graph (KG), has drawn significant attention in recent years. However, the predictive power of KGC methods is often limited by the completeness of the existing knowledge graphs from different sources and languages. In monolingual and multilingual settings, KGs are potentially complementary to each other. In this paper, we study the problem of multi-KG completion, where we focus on maximizing the collective knowledge from different KGs to alleviate the incompleteness of individual KGs. Specifically, we propose a novel method called CKGC-CKD that uses relation-aware graph convolutional network encoder models on both individual KGs and a large fused KG in which seed alignments between KGs are regarded as edges for message propagation. An additional mutual knowledge distillation mechanism is also employed to maximize the knowledge transfer between the models of "global" fused KG and the "local" individual KGs. Experimental results on multilingual datasets have shown that our method outperforms all state-of-the-art models in the KGC task.