Attention-Enhanced Deep Learning Ensemble for Breast Density Classification in Mammography

Breast density assessment is a crucial component of mammographic interpretation, with high breast density (BI-RADS categories C and D) representing both a significant risk factor for developing breast cancer and a technical challenge for tumor detection. This study proposes an automated deep learning system for robust binary classification of breast density (low: A/B vs. high: C/D) using the VinDr-Mammo dataset. We implemented and compared four advanced convolutional neural networks: ResNet18, ResNet50, EfficientNet-B0, and DenseNet121, each enhanced with channel attention mechanisms. To address the inherent class imbalance, we developed a novel Combined Focal Label Smoothing Loss function that integrates focal loss, label smoothing, and class-balanced weighting. Our preprocessing pipeline incorporated advanced techniques, including contrast-limited adaptive histogram equalization (CLAHE) and comprehensive data augmentation. The individual models were combined through an optimized ensemble voting approach, achieving superior performance (AUC: 0.963, F1-score: 0.952) compared to any single model. This system demonstrates significant potential to standardize density assessments in clinical practice, potentially improving screening efficiency and early cancer detection rates while reducing inter-observer variability among radiologists.

MLIR: A Compiler Infrastructure for the End of Moore's Law

This work presents MLIR, a novel approach to building reusable and extensible compiler infrastructure. MLIR aims to address software fragmentation, improve compilation for heterogeneous hardware, significantly reduce the cost of building domain specific compilers, and aid in connecting existing compilers together. MLIR facilitates the design and implementation of code generators, translators and optimizers at different levels of abstraction and also across application domains, hardware targets and execution environments. The contribution of this work includes (1) discussion of MLIR as a research artifact, built for extension and evolution, and identifying the challenges and opportunities posed by this novel design point in design, semantics, optimization specification, system, and engineering. (2) evaluation of MLIR as a generalized infrastructure that reduces the cost of building compilers-describing diverse use-cases to show research and educational opportunities for future programming languages, compilers, execution environments, and computer architecture. The paper also presents the rationale for MLIR, its original design principles, structures and semantics.