This paper presents a novel approach to automatic fetal brain biometry motivated by needs in low- and medium- income countries. Specifically, we leverage high-end (HE) ultrasound images to build a biometry solution for low-cost (LC) point-of-care ultrasound images. We propose a novel unsupervised domain adaptation approach to train deep models to be invariant to significant image distribution shift between the image types. Our proposed method, which employs a Dual Adversarial Calibration (DAC) framework, consists of adversarial pathways which enforce model invariance to; i) adversarial perturbations in the feature space derived from LC images, and ii) appearance domain discrepancy. Our Dual Adversarial Calibration method estimates transcerebellar diameter and head circumference on images from low-cost ultrasound devices with a mean absolute error (MAE) of 2.43mm and 1.65mm, compared with 7.28 mm and 5.65 mm respectively for SOTA.
Deep learning models with large learning capacities often overfit to medical imaging datasets. This is because training sets are often relatively small due to the significant time and financial costs incurred in medical data acquisition and labelling. Data augmentation is therefore often used to expand the availability of training data and to increase generalization. However, augmentation strategies are often chosen on an ad-hoc basis without justification. In this paper, we present an augmentation policy search method with the goal of improving model classification performance. We include in the augmentation policy search additional transformations that are often used in medical image analysis and evaluate their performance. In addition, we extend the augmentation policy search to include non-linear mixed-example data augmentation strategies. Using these learned policies, we show that principled data augmentation for medical image model training can lead to significant improvements in ultrasound standard plane detection, with an an average F1-score improvement of 7.0% overall over naive data augmentation strategies in ultrasound fetal standard plane classification. We find that the learned representations of ultrasound images are better clustered and defined with optimized data augmentation.