Simulation-to-Real First-Break Segmentation for Efficient Inversion in Musculoskeletal Ultrasound Tomography

Full-waveform inversion (FWI) is a promising strategy for quantitative musculoskeletal ultrasound computed tomography (USCT), but bone-related scattering, attenuation, and signal degradation make it highly sensitive to the accuracy of the initial acoustic-property distributions and prone to cycle skipping. First-arrival traveltimes provide important kinematic information for initial-model construction, yet conventional trace-wise picking is unreliable when arrivals are weak, spatially heterogeneous, or buried in system noise. We propose a learning-assisted reconstruction pipeline that combines segmentation-based first-arrival extraction with hybrid full-waveform inversion (HFWI), which incorporates Rytov-approximation-based traveltime information together with waveform fitting during the early inversion stage. A lightweight 2D U-Net treats the first-arrival trajectory across receiver channels as a first-break segmentation target and exploits its spatial continuity rather than processing each trace independently. To address both limited manual annotations and the simulation-to-real gap, the network is pretrained on task-specific simulations augmented with real system-noise recordings, followed by stage-wise training with progressively increased signal degradation and decoder-only fine-tuning using limited weakly labeled experimental data. The method is evaluated on in vitro phantom, ex vivo bovine-limb, and in vivo human-thigh datasets. Compared with conventional STA/LTA picking, the proposed network yields more spatially coherent first-arrival trajectories, lower mean extraction errors, and processes a full-matrix-capture dataset within seconds. When integrated into HFWI, the extracted arrivals improve initial-model construction and lead to stable subsequent FWI reconstructions, including challenging cases with estimated local first-arrival SNRs below 3 dB.

ADIAS: Automated Design of Interactive Agentic Systems

Automated agent design improves agent harnesses through iterative revision, evaluation, and feedback summarization. Existing methods are largely candidate-centric: cross-round experience is organized around candidate agents, which leaves the repair progress implicit. This causes inefficient repair targeting, slow consolidation of partial progress, and propagation of ineffective interventions across rounds. Therefore, we formulate issue-centric agent optimization, in which repair progress is carried forward as an explicit persistent issue state to guide optimization, rather than re-derived from candidate history in each round. We instantiate the formulation in ADIAS, a framework for automated full-code agent design with two mechanisms. A persistent issue state maintains stable issue identities, lifecycle status, supporting evidence, and intervention-outcome histories. Issue-guided optimization uses this state to jointly propose repair targets and revision directions for subsequent focused full-code modification. Across five interactive benchmarks, ADIAS outperforms the strongest baseline by 25.2% on average and achieves consistent gains across four backbone models. Controlled ablations further show that removing persistent issue state or replacing issue-centric revision with candidate-centric policies leads to performance drops of up to 40.7%.

When Reasoning Hurts Legal Drafting: The Verbalization Bottleneck in Patent Claim Generation

Patent claim drafting is a challenging legal drafting task that requires technical expertise, precise linguistic control, strict adherence to formal conventions, and the preservation of complex logical relationships among claim elements. While Chain-of-Thought (CoT) prompting has been widely used to improve the reasoning capabilities of large language models (LLMs), recent evidence suggests that its benefits may be limited, or even negative, in highly structured or pattern-sensitive tasks. Therefore, this paper investigates whether CoT prompting benefits patent claim generation. We propose a task-specific CoT method for patent claim generation and evaluate its effectiveness through both automatic metrics and human expert assessment. Our results show that reasoning-enhanced prompting can improve claim quality. Moreover, we demonstrate a counter-intuitive but important empirical finding: implicit CoT, where reasoning is kept internal rather than explicitly verbalized, consistently outperforms explicit CoT. Through systematic analysis, we show that explicit CoT can introduce an unnecessary information bottleneck for claim generation. Verbalized reasoning may compromise the quality of final outputs through three specific mechanisms: abstraction of critical details, disruption of internalized generation patterns, and cascading error propagation. Our findings provide new insights into legal tasks and CoT applications.

Hybrid Full Waveform Inversion Assisted by Rytov Approximation for Musculoskeletal Ultrasound Computed Tomography

Ultrasound computed tomography is emerging as a promising safe and accessible modality for soft-tissue medical imaging, with full waveform inversion playing a key role in unlocking its full potential for high-resolution, quantitative reconstructions. Frequency domain full waveform inversion (FDFWI) for reconstructing spatial maps of acoustic properties in the musculoskeletal system is highly sensitive to the quality of low-frequency signals, making the final imaging outcome vulnerable to issues such as inappropriate initial models and strong scatterings related to bones. To address these challenges, we propose a hybrid full waveform inversion (HFWI) algorithm that incorporates a traveltime inversion algorithm based on the generalized Rytov approximation into the FDFWI framework. This hybrid strategy enhances early-stage inversion quality and substantially reduces sensitivity to the initial model, all while maintaining computational efficiency. Importantly, HFWI achieves results comparable to those obtained using well-constructed initial models, without incurring extra computational cost, thus enabling accurate imaging under realistic, bandwidth-limited conditions. In addition, we introduce a near real-time strategy to update first-arrival traveltimes based on forward-scattered phase variations without requiring extra wavefield simulations. Numerical simulations, as well as \textit{in vitro} and \textit{in vivo} experiments confirm the robustness and efficiency of the proposed approach. HFWI also shows promise to extend to more complex scenarios of musculoskeletal parametric reconstruction.

Reasoning for Hierarchical Text Classification: The Case of Patents

Hierarchical text classification (HTC) assigns documents to multiple levels of a pre-defined taxonomy. Automated patent subject classification represents one of the hardest HTC scenarios because of domain knowledge difficulty and a huge number of labels. Prior approaches only output a flat label set, which offers little insight into the reason behind predictions. Therefore, we propose Reasoning for Hierarchical Classification (RHC), a novel framework that reformulates HTC as a step-by-step reasoning task to sequentially deduce hierarchical labels. RHC trains large language models (LLMs) in two stages: a cold-start stage that aligns outputs with chain-of-thought (CoT) reasoning format and a reinforcement learning (RL) stage to enhance multi-step reasoning ability. RHC demonstrates four advantages in our experiments. (1) Effectiveness: RHC surpasses previous baselines and outperforms the supervised fine-tuning counterparts by approximately 3% in accuracy and macro F1. (2) Explainability: RHC produces natural-language justifications before prediction to facilitate human inspection. (3) Scalability: RHC scales favorably with model size with larger gains compared to standard fine-tuning. (4) Applicability: Beyond patents, we further demonstrate that RHC achieves state-of-the-art performance on other widely used HTC benchmarks, which highlights its broad applicability.

Enriching Patent Claim Generation with European Patent Dataset

Drafting patent claims is time-intensive, costly, and requires professional skill. Therefore, researchers have investigated large language models (LLMs) to assist inventors in writing claims. However, existing work has largely relied on datasets from the United States Patent and Trademark Office (USPTO). To enlarge research scope regarding various jurisdictions, drafting conventions, and legal standards, we introduce EPD, a European patent dataset. EPD presents rich textual data and structured metadata to support multiple patent-related tasks, including claim generation. This dataset enriches the field in three critical aspects: (1) Jurisdictional diversity: Patents from different offices vary in legal and drafting conventions. EPD fills a critical gap by providing a benchmark for European patents to enable more comprehensive evaluation. (2) Quality improvement: EPD offers high-quality granted patents with finalized and legally approved texts, whereas others consist of patent applications that are unexamined or provisional. Experiments show that LLMs fine-tuned on EPD significantly outperform those trained on previous datasets and even GPT-4o in claim quality and cross-domain generalization. (3) Real-world simulation: We propose a difficult subset of EPD to better reflect real-world challenges of claim generation. Results reveal that all tested LLMs perform substantially worse on these challenging samples, which highlights the need for future research.

Towards Better Evaluation for Generated Patent Claims

Patent claims define the scope of protection and establish the legal boundaries of an invention. Drafting these claims is a complex and time-consuming process that usually requires the expertise of skilled patent attorneys, which can form a large access barrier for many small enterprises. To solve these challenges, researchers have investigated the use of large language models (LLMs) for automating patent claim generation. However, existing studies highlight inconsistencies between automated evaluation metrics and human expert assessments. To bridge this gap, we introduce Patent-CE, the first comprehensive benchmark for evaluating patent claims. Patent-CE includes comparative claim evaluations annotated by patent experts, focusing on five key criteria: feature completeness, conceptual clarity, terminology consistency, logical linkage, and overall quality. Additionally, we propose PatClaimEval, a novel multi-dimensional evaluation method specifically designed for patent claims. Our experiments demonstrate that PatClaimEval achieves the highest correlation with human expert evaluations across all assessment criteria among all tested metrics. This research provides the groundwork for more accurate evaluations of automated patent claim generation systems.

Patent-CR: A Dataset for Patent Claim Revision

This paper presents Patent-CR, the first dataset created for the patent claim revision task in English. It includes both initial patent applications rejected by patent examiners and the final granted versions. Unlike normal text revision tasks that predominantly focus on enhancing sentence quality, such as grammar correction and coherence improvement, patent claim revision aims at ensuring the claims meet stringent legal criteria. These criteria are beyond novelty and inventiveness, including clarity of scope, technical accuracy, language precision, and legal robustness. We assess various large language models (LLMs) through professional human evaluation, including general LLMs with different sizes and architectures, text revision models, and domain-specific models. Our results indicate that LLMs often bring ineffective edits that deviate from the target revisions. In addition, domain-specific models and the method of fine-tuning show promising results. Notably, GPT-4 outperforms other tested LLMs, but further revisions are still necessary to reach the examination standard. Furthermore, we demonstrate the inconsistency between automated and human evaluation results, suggesting that GPT-4-based automated evaluation has the highest correlation with human judgment. This dataset, along with our preliminary empirical research, offers invaluable insights for further exploration in patent claim revision.

Can Large Language Models Generate High-quality Patent Claims?

Large language models (LLMs) have shown exceptional performance across various text generation tasks but remain under-explored in the patent domain, which offers highly structured and precise language. This paper constructs a dataset to investigate the performance of current LLMs in patent claim generation. Our results demonstrate that generating claims based on patent descriptions outperforms previous research relying on abstracts. Interestingly, current patent-specific LLMs perform much worse than state-of-the-art general LLMs, highlighting the necessity for future research on in-domain LLMs. We also find that LLMs can produce high-quality first independent claims, but their performances markedly decrease for subsequent dependent claims. Moreover, fine-tuning can enhance the completeness of inventions' features, conceptual clarity, and feature linkage. Among the tested LLMs, GPT-4 demonstrates the best performance in comprehensive human evaluations by patent experts, with better feature coverage, conceptual clarity, and technical coherence. Despite these capabilities, comprehensive revision and modification are still necessary to pass rigorous patent scrutiny and ensure legal robustness.

Artificial Intelligence Exploring the Patent Field

Advanced language-processing and machine-learning techniques promise massive efficiency improvements in the previously widely manual field of patent and technical knowledge management. This field presents large-scale and complex data with very precise contents and language representation of those contents. Particularly, patent texts can differ from mundane texts in various aspects, which entails significant opportunities and challenges. This paper presents a systematic overview of patent-related tasks and popular methodologies with a special focus on evolving and promising techniques. Language processing and particularly large language models as well as the recent boost of general generative methods promise to become game changers in the patent field. The patent literature and the fact-based argumentative procedures around patents appear almost as an ideal use case. However, patents entail a number of difficulties with which existing models struggle. The paper introduces fundamental aspects of patents and patent-related data that affect technology that wants to explore or manage them. It further reviews existing methods and approaches and points out how important reliable and unbiased evaluation metrics become. Although research has made substantial progress on certain tasks, the performance across many others remains suboptimal, sometimes because of either the special nature of patents and their language or inconsistencies between legal terms and the everyday meaning of terms. Moreover, yet few methods have demonstrated the ability to produce satisfactory text for specific sections of patents. By pointing out key developments, opportunities, and gaps, we aim to encourage further research and accelerate the advancement of this field.