Few shot chain-of-thought driven reasoning to prompt LLMs for open ended medical question answering

Large Language models (LLMs) have demonstrated significant potential in transforming healthcare by automating tasks such as clinical documentation, information retrieval, and decision support. In this aspect, carefully engineered prompts have emerged as a powerful tool for using LLMs for medical scenarios, e.g., patient clinical scenarios. In this paper, we propose a modified version of the MedQA-USMLE dataset, which is subjective, to mimic real-life clinical scenarios. We explore the Chain of Thought (CoT) reasoning based on subjective response generation for the modified MedQA-USMLE dataset with appropriate LM-driven forward reasoning for correct responses to the medical questions. Keeping in mind the importance of response verification in the medical setting, we utilize a reward training mechanism whereby the language model also provides an appropriate verified response for a particular response to a clinical question. In this regard, we also include human-in-the-loop for different evaluation aspects. We develop better in-contrast learning strategies by modifying the 5-shot-codex-CoT-prompt from arXiv:2207.08143 for the subjective MedQA dataset and developing our incremental-reasoning prompt. Our evaluations show that the incremental reasoning prompt performs better than the modified codex prompt in certain scenarios. We also show that greedy decoding with the incremental reasoning method performs better than other strategies, such as prompt chaining and eliminative reasoning.

FESS Loss: Feature-Enhanced Spatial Segmentation Loss for Optimizing Medical Image Analysis

Medical image segmentation is a critical process in the field of medical imaging, playing a pivotal role in diagnosis, treatment, and research. It involves partitioning of an image into multiple regions, representing distinct anatomical or pathological structures. Conventional methods often grapple with the challenge of balancing spatial precision and comprehensive feature representation due to their reliance on traditional loss functions. To overcome this, we propose Feature-Enhanced Spatial Segmentation Loss (FESS Loss), that integrates the benefits of contrastive learning (which extracts intricate features, particularly in the nuanced domain of medical imaging) with the spatial accuracy inherent in the Dice loss. The objective is to augment both spatial precision and feature-based representation in the segmentation of medical images. FESS Loss signifies a notable advancement, offering a more accurate and refined segmentation process, ultimately contributing to heightened precision in the analysis of medical images. Further, FESS loss demonstrates superior performance in limited annotated data availability scenarios often present in the medical domain.