Abstract:Discovering complex causal dependencies in temporal point processes (TPPs) is critical for modeling real-world event sequences. Existing methods typically rely on static or first-order causal structures, overlooking the multi-order and time-varying nature of causal relationships. In this paper, we propose MOCHA, a novel framework for discovering multi-order dynamic causality in TPPs. MOCHA characterizes multi-order influences as multi-hop causal paths over a latent time-evolving graph. To model such dynamics, we introduce a time-varying directed acyclic graph (DAG) with learnable structural weights, where acyclicity and sparsity constraints are enforced to ensure structural validity. We design an end-to-end differentiable framework that jointly models causal discovery and TPP dynamics, enabling accurate event prediction and revealing interpretable structures. Extensive experiments on real-world datasets demonstrate that MOCHA not only achieves state-of-the-art performance in event prediction, but also reveals meaningful and interpretable causal structures.
Abstract:Temporal Point Processes (TPPs) are widely used for modeling event sequences in various medical domains, such as disease onset prediction, progression analysis, and clinical decision support. Although TPPs effectively capture temporal dynamics, their lack of interpretability remains a critical challenge. Recent advancements have introduced interpretable TPPs. However, these methods fail to incorporate numerical features, thereby limiting their ability to generate precise predictions. To address this issue, we propose Hybrid-Rule Temporal Point Processes (HRTPP), a novel framework that integrates temporal logic rules with numerical features, improving both interpretability and predictive accuracy in event modeling. HRTPP comprises three key components: basic intensity for intrinsic event likelihood, rule-based intensity for structured temporal dependencies, and numerical feature intensity for dynamic probability modulation. To effectively discover valid rules, we introduce a two-phase rule mining strategy with Bayesian optimization. To evaluate our method, we establish a multi-criteria assessment framework, incorporating rule validity, model fitting, and temporal predictive accuracy. Experimental results on real-world medical datasets demonstrate that HRTPP outperforms state-of-the-art interpretable TPPs in terms of predictive performance and clinical interpretability. In case studies, the rules extracted by HRTPP explain the disease progression, offering valuable contributions to medical diagnosis.