Abstract:Despite the wide adoption of Large Language Models (LLM)s, clinical decision support systems face a critical challenge: achieving high predictive accuracy while generating explanations aligned with the predictions. Current approaches suffer from exposure bias leading to misaligned explanations. We propose Reason2Decide, a two-stage training framework that addresses key challenges in self-rationalization, including exposure bias and task separation. In Stage-1, our model is trained on rationale generation, while in Stage-2, we jointly train on label prediction and rationale generation, applying scheduled sampling to gradually transition from conditioning on gold labels to model predictions. We evaluate Reason2Decide on three medical datasets, including a proprietary triage dataset and public biomedical QA datasets. Across model sizes, Reason2Decide outperforms other fine-tuning baselines and some zero-shot LLMs in prediction (F1) and rationale fidelity (BERTScore, BLEU, LLM-as-a-Judge). In triage, Reason2Decide is rationale source-robust across LLM-generated, nurse-authored, and nurse-post-processed rationales. In our experiments, while using only LLM-generated rationales in Stage-1, Reason2Decide outperforms other fine-tuning variants. This indicates that LLM-generated rationales are suitable for pretraining models, reducing reliance on human annotations. Remarkably, Reason2Decide achieves these gains with models 40x smaller than contemporary foundation models, making clinical reasoning more accessible for resource-constrained deployments while still providing explainable decision support.




Abstract:Developing the capacity to effectively search for requisite datasets is an urgent requirement to assist data users in identifying relevant datasets considering the very limited available metadata. For this challenge, the utilization of third-party data is emerging as a valuable source for improvement. Our research introduces a new architecture for data exploration which employs a form of Retrieval-Augmented Generation (RAG) to enhance metadata-based data discovery. The system integrates large language models (LLMs) with external vector databases to identify semantic relationships among diverse types of datasets. The proposed framework offers a new method for evaluating semantic similarity among heterogeneous data sources and for improving data exploration. Our study includes experimental results on four critical tasks: 1) recommending similar datasets, 2) suggesting combinable datasets, 3) estimating tags, and 4) predicting variables. Our results demonstrate that RAG can enhance the selection of relevant datasets, particularly from different categories, when compared to conventional metadata approaches. However, performance varied across tasks and models, which confirms the significance of selecting appropriate techniques based on specific use cases. The findings suggest that this approach holds promise for addressing challenges in data exploration and discovery, although further refinement is necessary for estimation tasks.