FastSurfer-HypVINN: Automated sub-segmentation of the hypothalamus and adjacent structures on high-resolutional brain MRI

The hypothalamus plays a crucial role in the regulation of a broad range of physiological, behavioural, and cognitive functions. However, despite its importance, only a few small-scale neuroimaging studies have investigated its substructures, likely due to the lack of fully automated segmentation tools to address scalability and reproducibility issues of manual segmentation. While the only previous attempt to automatically sub-segment the hypothalamus with a neural network showed promise for 1.0 mm isotropic T1-weighted (T1w) MRI, there is a need for an automated tool to sub-segment also high-resolutional (HiRes) MR scans, as they are becoming widely available, and include structural detail also from multi-modal MRI. We, therefore, introduce a novel, fast, and fully automated deep learning method named HypVINN for sub-segmentation of the hypothalamus and adjacent structures on 0.8 mm isotropic T1w and T2w brain MR images that is robust to missing modalities. We extensively validate our model with respect to segmentation accuracy, generalizability, in-session test-retest reliability, and sensitivity to replicate hypothalamic volume effects (e.g. sex-differences). The proposed method exhibits high segmentation performance both for standalone T1w images as well as for T1w/T2w image pairs. Even with the additional capability to accept flexible inputs, our model matches or exceeds the performance of state-of-the-art methods with fixed inputs. We, further, demonstrate the generalizability of our method in experiments with 1.0 mm MR scans from both the Rhineland Study and the UK Biobank. Finally, HypVINN can perform the segmentation in less than a minute (GPU) and will be available in the open source FastSurfer neuroimaging software suite, offering a validated, efficient, and scalable solution for evaluating imaging-derived phenotypes of the hypothalamus.

How Much Temporal Long-Term Context is Needed for Action Segmentation?

Modeling long-term context in videos is crucial for many fine-grained tasks including temporal action segmentation. An interesting question that is still open is how much long-term temporal context is needed for optimal performance. While transformers can model the long-term context of a video, this becomes computationally prohibitive for long videos. Recent works on temporal action segmentation thus combine temporal convolutional networks with self-attentions that are computed only for a local temporal window. While these approaches show good results, their performance is limited by their inability to capture the full context of a video. In this work, we try to answer how much long-term temporal context is required for temporal action segmentation by introducing a transformer-based model that leverages sparse attention to capture the full context of a video. We compare our model with the current state of the art on three datasets for temporal action segmentation, namely 50Salads, Breakfast, and Assembly101. Our experiments show that modeling the full context of a video is necessary to obtain the best performance for temporal action segmentation.

Robust Action Segmentation from Timestamp Supervision

Action segmentation is the task of predicting an action label for each frame of an untrimmed video. As obtaining annotations to train an approach for action segmentation in a fully supervised way is expensive, various approaches have been proposed to train action segmentation models using different forms of weak supervision, e.g., action transcripts, action sets, or more recently timestamps. Timestamp supervision is a promising type of weak supervision as obtaining one timestamp per action is less expensive than annotating all frames, but it provides more information than other forms of weak supervision. However, previous works assume that every action instance is annotated with a timestamp, which is a restrictive assumption since it assumes that annotators do not miss any action. In this work, we relax this restrictive assumption and take missing annotations for some action instances into account. We show that our approach is more robust to missing annotations compared to other approaches and various baselines.

Taylor Swift: Taylor Driven Temporal Modeling for Swift Future Frame Prediction

While recurrent neural networks (RNNs) demonstrate outstanding capabilities in future video frame prediction, they model dynamics in a discrete time space and sequentially go through all frames until the desired future temporal step is reached. RNNs are therefore prone to accumulate the error as the number of future frames increases. In contrast, partial differential equations (PDEs) model physical phenomena like dynamics in continuous time space, however, current PDE-based approaches discretize the PDEs using e.g., the forward Euler method. In this work, we therefore propose to approximate the motion in a video by a continuous function using the Taylor series. To this end, we introduce TayloSwiftNet, a novel convolutional neural network that learns to estimate the higher order terms of the Taylor series for a given input video. TayloSwiftNet can swiftly predict any desired future frame in just one forward pass and change the temporal resolution on-the-fly. The experimental results on various datasets demonstrate the superiority of our model.