Overcoming Dimensional Collapse in Self-supervised Contrastive Learning for Medical Image Segmentation

Self-supervised learning (SSL) approaches have achieved great success when the amount of labeled data is limited. Within SSL, models learn robust feature representations by solving pretext tasks. One such pretext task is contrastive learning, which involves forming pairs of similar and dissimilar input samples, guiding the model to distinguish between them. In this work, we investigate the application of contrastive learning to the domain of medical image analysis. Our findings reveal that MoCo v2, a state-of-the-art contrastive learning method, encounters dimensional collapse when applied to medical images. This is attributed to the high degree of inter-image similarity shared between the medical images. To address this, we propose two key contributions: local feature learning and feature decorrelation. Local feature learning improves the ability of the model to focus on the local regions of the image, while feature decorrelation removes the linear dependence among the features. Our experimental findings demonstrate that our contributions significantly enhance the model's performance in the downstream task of medical segmentation, both in the linear evaluation and full fine-tuning settings. This work illustrates the importance of effectively adapting SSL techniques to the characteristics of medical imaging tasks. The source code will be made publicly available at: https://github.com/CAMMA-public/med-moco

The Endoscapes Dataset for Surgical Scene Segmentation, Object Detection, and Critical View of Safety Assessment: Official Splits and Benchmark

This technical report provides a detailed overview of Endoscapes, a dataset of laparoscopic cholecystectomy (LC) videos with highly intricate annotations targeted at automated assessment of the Critical View of Safety (CVS). Endoscapes comprises 201 LC videos with frames annotated sparsely but regularly with segmentation masks, bounding boxes, and CVS assessment by three different clinical experts. Altogether, there are 11090 frames annotated with CVS and 1933 frames annotated with tool and anatomy bounding boxes from the 201 videos, as well as an additional 422 frames from 50 of the 201 videos annotated with tool and anatomy segmentation masks. In this report, we provide detailed dataset statistics (size, class distribution, dataset splits, etc.) and a comprehensive performance benchmark for instance segmentation, object detection, and CVS prediction. The dataset and model checkpoints are publically available at https://github.com/CAMMA-public/Endoscapes.

ST(OR)2: Spatio-Temporal Object Level Reasoning for Activity Recognition in the Operating Room

Surgical robotics holds much promise for improving patient safety and clinician experience in the Operating Room (OR). However, it also comes with new challenges, requiring strong team coordination and effective OR management. Automatic detection of surgical activities is a key requirement for developing AI-based intelligent tools to tackle these challenges. The current state-of-the-art surgical activity recognition methods however operate on image-based representations and depend on large-scale labeled datasets whose collection is time-consuming and resource-expensive. This work proposes a new sample-efficient and object-based approach for surgical activity recognition in the OR. Our method focuses on the geometric arrangements between clinicians and surgical devices, thus utilizing the significant object interaction dynamics in the OR. We conduct experiments in a low-data regime study for long video activity recognition. We also benchmark our method againstother object-centric approaches on clip-level action classification and show superior performance.

Challenges in Multi-centric Generalization: Phase and Step Recognition in Roux-en-Y Gastric Bypass Surgery

Most studies on surgical activity recognition utilizing Artificial intelligence (AI) have focused mainly on recognizing one type of activity from small and mono-centric surgical video datasets. It remains speculative whether those models would generalize to other centers. In this work, we introduce a large multi-centric multi-activity dataset consisting of 140 videos (MultiBypass140) of laparoscopic Roux-en-Y gastric bypass (LRYGB) surgeries performed at two medical centers: the University Hospital of Strasbourg (StrasBypass70) and Inselspital, Bern University Hospital (BernBypass70). The dataset has been fully annotated with phases and steps. Furthermore, we assess the generalizability and benchmark different deep learning models in 7 experimental studies: 1) Training and evaluation on BernBypass70; 2) Training and evaluation on StrasBypass70; 3) Training and evaluation on the MultiBypass140; 4) Training on BernBypass70, evaluation on StrasBypass70; 5) Training on StrasBypass70, evaluation on BernBypass70; Training on MultiBypass140, evaluation 6) on BernBypass70 and 7) on StrasBypass70. The model's performance is markedly influenced by the training data. The worst results were obtained in experiments 4) and 5) confirming the limited generalization capabilities of models trained on mono-centric data. The use of multi-centric training data, experiments 6) and 7), improves the generalization capabilities of the models, bringing them beyond the level of independent mono-centric training and validation (experiments 1) and 2)). MultiBypass140 shows considerable variation in surgical technique and workflow of LRYGB procedures between centers. Therefore, generalization experiments demonstrate a remarkable difference in model performance. These results highlight the importance of multi-centric datasets for AI model generalization to account for variance in surgical technique and workflows.

Encoding Surgical Videos as Latent Spatiotemporal Graphs for Object and Anatomy-Driven Reasoning

Recently, spatiotemporal graphs have emerged as a concise and elegant manner of representing video clips in an object-centric fashion, and have shown to be useful for downstream tasks such as action recognition. In this work, we investigate the use of latent spatiotemporal graphs to represent a surgical video in terms of the constituent anatomical structures and tools and their evolving properties over time. To build the graphs, we first predict frame-wise graphs using a pre-trained model, then add temporal edges between nodes based on spatial coherence and visual and semantic similarity. Unlike previous approaches, we incorporate long-term temporal edges in our graphs to better model the evolution of the surgical scene and increase robustness to temporary occlusions. We also introduce a novel graph-editing module that incorporates prior knowledge and temporal coherence to correct errors in the graph, enabling improved downstream task performance. Using our graph representations, we evaluate two downstream tasks, critical view of safety prediction and surgical phase recognition, obtaining strong results that demonstrate the quality and flexibility of the learned representations. Code is available at github.com/CAMMA-public/SurgLatentGraph.

TRUSTED: The Paired 3D Transabdominal Ultrasound and CT Human Data for Kidney Segmentation and Registration Research

Inter-modal image registration (IMIR) and image segmentation with abdominal Ultrasound (US) data has many important clinical applications, including image-guided surgery, automatic organ measurement and robotic navigation. However, research is severely limited by the lack of public datasets. We propose TRUSTED (the Tridimensional Renal Ultra Sound TomodEnsitometrie Dataset), comprising paired transabdominal 3DUS and CT kidney images from 48 human patients (96 kidneys), including segmentation, and anatomical landmark annotations by two experienced radiographers. Inter-rater segmentation agreement was over 94 (Dice score), and gold-standard segmentations were generated using the STAPLE algorithm. Seven anatomical landmarks were annotated, important for IMIR systems development and evaluation. To validate the dataset's utility, 5 competitive Deep Learning models for automatic kidney segmentation were benchmarked, yielding average DICE scores from 83.2% to 89.1% for CT, and 61.9% to 79.4% for US images. Three IMIR methods were benchmarked, and Coherent Point Drift performed best with an average Target Registration Error of 4.53mm. The TRUSTED dataset may be used freely researchers to develop and validate new segmentation and IMIR methods.

Surgical Action Triplet Detection by Mixed Supervised Learning of Instrument-Tissue Interactions

Surgical action triplets describe instrument-tissue interactions as (instrument, verb, target) combinations, thereby supporting a detailed analysis of surgical scene activities and workflow. This work focuses on surgical action triplet detection, which is challenging but more precise than the traditional triplet recognition task as it consists of joint (1) localization of surgical instruments and (2) recognition of the surgical action triplet associated with every localized instrument. Triplet detection is highly complex due to the lack of spatial triplet annotation. We analyze how the amount of instrument spatial annotations affects triplet detection and observe that accurate instrument localization does not guarantee better triplet detection due to the risk of erroneous associations with the verbs and targets. To solve the two tasks, we propose MCIT-IG, a two-stage network, that stands for Multi-Class Instrument-aware Transformer-Interaction Graph. The MCIT stage of our network models per class embedding of the targets as additional features to reduce the risk of misassociating triplets. Furthermore, the IG stage constructs a bipartite dynamic graph to model the interaction between the instruments and targets, cast as the verbs. We utilize a mixed-supervised learning strategy that combines weak target presence labels for MCIT and pseudo triplet labels for IG to train our network. We observed that complementing minimal instrument spatial annotations with target embeddings results in better triplet detection. We evaluate our model on the CholecT50 dataset and show improved performance on both instrument localization and triplet detection, topping the leaderboard of the CholecTriplet challenge in MICCAI 2022.

Weakly Supervised Temporal Convolutional Networks for Fine-grained Surgical Activity Recognition

Automatic recognition of fine-grained surgical activities, called steps, is a challenging but crucial task for intelligent intra-operative computer assistance. The development of current vision-based activity recognition methods relies heavily on a high volume of manually annotated data. This data is difficult and time-consuming to generate and requires domain-specific knowledge. In this work, we propose to use coarser and easier-to-annotate activity labels, namely phases, as weak supervision to learn step recognition with fewer step annotated videos. We introduce a step-phase dependency loss to exploit the weak supervision signal. We then employ a Single-Stage Temporal Convolutional Network (SS-TCN) with a ResNet-50 backbone, trained in an end-to-end fashion from weakly annotated videos, for temporal activity segmentation and recognition. We extensively evaluate and show the effectiveness of the proposed method on a large video dataset consisting of 40 laparoscopic gastric bypass procedures and the public benchmark CATARACTS containing 50 cataract surgeries.

CholecTriplet2022: Show me a tool and tell me the triplet -- an endoscopic vision challenge for surgical action triplet detection

Formalizing surgical activities as triplets of the used instruments, actions performed, and target anatomies is becoming a gold standard approach for surgical activity modeling. The benefit is that this formalization helps to obtain a more detailed understanding of tool-tissue interaction which can be used to develop better Artificial Intelligence assistance for image-guided surgery. Earlier efforts and the CholecTriplet challenge introduced in 2021 have put together techniques aimed at recognizing these triplets from surgical footage. Estimating also the spatial locations of the triplets would offer a more precise intraoperative context-aware decision support for computer-assisted intervention. This paper presents the CholecTriplet2022 challenge, which extends surgical action triplet modeling from recognition to detection. It includes weakly-supervised bounding box localization of every visible surgical instrument (or tool), as the key actors, and the modeling of each tool-activity in the form of <instrument, verb, target> triplet. The paper describes a baseline method and 10 new deep learning algorithms presented at the challenge to solve the task. It also provides thorough methodological comparisons of the methods, an in-depth analysis of the obtained results, their significance, and useful insights for future research directions and applications in surgery.