Interpretable Models for Detecting and Monitoring Elevated Intracranial Pressure

Detecting elevated intracranial pressure (ICP) is crucial in diagnosing and managing various neurological conditions. These fluctuations in pressure are transmitted to the optic nerve sheath (ONS), resulting in changes to its diameter, which can then be detected using ultrasound imaging devices. However, interpreting sonographic images of the ONS can be challenging. In this work, we propose two systems that actively monitor the ONS diameter throughout an ultrasound video and make a final prediction as to whether ICP is elevated. To construct our systems, we leverage subject matter expert (SME) guidance, structuring our processing pipeline according to their collection procedure, while also prioritizing interpretability and computational efficiency. We conduct a number of experiments, demonstrating that our proposed systems are able to outperform various baselines. One of our SMEs then manually validates our top system's performance, lending further credibility to our approach while demonstrating its potential utility in a clinical setting.

Event-to-Video Conversion for Overhead Object Detection

Collecting overhead imagery using an event camera is desirable due to the energy efficiency of the image sensor compared to standard cameras. However, event cameras complicate downstream image processing, especially for complex tasks such as object detection. In this paper, we investigate the viability of event streams for overhead object detection. We demonstrate that across a number of standard modeling approaches, there is a significant gap in performance between dense event representations and corresponding RGB frames. We establish that this gap is, in part, due to a lack of overlap between the event representations and the pre-training data used to initialize the weights of the object detectors. Then, we apply event-to-video conversion models that convert event streams into gray-scale video to close this gap. We demonstrate that this approach results in a large performance increase, outperforming even event-specific object detection techniques on our overhead target task. These results suggest that better alignment between event representations and existing large pre-trained models may result in greater short-term performance gains compared to end-to-end event-specific architectural improvements.

MobilePTX: Sparse Coding for Pneumothorax Detection Given Limited Training Examples

Point-of-Care Ultrasound (POCUS) refers to clinician-performed and interpreted ultrasonography at the patient's bedside. Interpreting these images requires a high level of expertise, which may not be available during emergencies. In this paper, we support POCUS by developing classifiers that can aid medical professionals by diagnosing whether or not a patient has pneumothorax. We decomposed the task into multiple steps, using YOLOv4 to extract relevant regions of the video and a 3D sparse coding model to represent video features. Given the difficulty in acquiring positive training videos, we trained a small-data classifier with a maximum of 15 positive and 32 negative examples. To counteract this limitation, we leveraged subject matter expert (SME) knowledge to limit the hypothesis space, thus reducing the cost of data collection. We present results using two lung ultrasound datasets and demonstrate that our model is capable of achieving performance on par with SMEs in pneumothorax identification. We then developed an iOS application that runs our full system in less than 4 seconds on an iPad Pro, and less than 8 seconds on an iPhone 13 Pro, labeling key regions in the lung sonogram to provide interpretable diagnoses.

StoryDALL-E: Adapting Pretrained Text-to-Image Transformers for Story Continuation

Recent advances in text-to-image synthesis have led to large pretrained transformers with excellent capabilities to generate visualizations from a given text. However, these models are ill-suited for specialized tasks like story visualization, which requires an agent to produce a sequence of images given a corresponding sequence of captions, forming a narrative. Moreover, we find that the story visualization task fails to accommodate generalization to unseen plots and characters in new narratives. Hence, we first propose the task of story continuation, where the generated visual story is conditioned on a source image, allowing for better generalization to narratives with new characters. Then, we enhance or 'retro-fit' the pretrained text-to-image synthesis models with task-specific modules for (a) sequential image generation and (b) copying relevant elements from an initial frame. Then, we explore full-model finetuning, as well as prompt-based tuning for parameter-efficient adaptation, of the pre-trained model. We evaluate our approach StoryDALL-E on two existing datasets, PororoSV and FlintstonesSV, and introduce a new dataset DiDeMoSV collected from a video-captioning dataset. We also develop a model StoryGANc based on Generative Adversarial Networks (GAN) for story continuation, and compare it with the StoryDALL-E model to demonstrate the advantages of our approach. We show that our retro-fitting approach outperforms GAN-based models for story continuation and facilitates copying of visual elements from the source image, thereby improving continuity in the generated visual story. Finally, our analysis suggests that pretrained transformers struggle to comprehend narratives containing several characters. Overall, our work demonstrates that pretrained text-to-image synthesis models can be adapted for complex and low-resource tasks like story continuation.

Improving Generation and Evaluation of Visual Stories via Semantic Consistency

Story visualization is an under-explored task that falls at the intersection of many important research directions in both computer vision and natural language processing. In this task, given a series of natural language captions which compose a story, an agent must generate a sequence of images that correspond to the captions. Prior work has introduced recurrent generative models which outperform text-to-image synthesis models on this task. However, there is room for improvement of generated images in terms of visual quality, coherence and relevance. We present a number of improvements to prior modeling approaches, including (1) the addition of a dual learning framework that utilizes video captioning to reinforce the semantic alignment between the story and generated images, (2) a copy-transform mechanism for sequentially-consistent story visualization, and (3) MART-based transformers to model complex interactions between frames. We present ablation studies to demonstrate the effect of each of these techniques on the generative power of the model for both individual images as well as the entire narrative. Furthermore, due to the complexity and generative nature of the task, standard evaluation metrics do not accurately reflect performance. Therefore, we also provide an exploration of evaluation metrics for the model, focused on aspects of the generated frames such as the presence/quality of generated characters, the relevance to captions, and the diversity of the generated images. We also present correlation experiments of our proposed automated metrics with human evaluations. Code and data available at: https://github.com/adymaharana/StoryViz

ManyModalQA: Modality Disambiguation and QA over Diverse Inputs

We present a new multimodal question answering challenge, ManyModalQA, in which an agent must answer a question by considering three distinct modalities: text, images, and tables. We collect our data by scraping Wikipedia and then utilize crowdsourcing to collect question-answer pairs. Our questions are ambiguous, in that the modality that contains the answer is not easily determined based solely upon the question. To demonstrate this ambiguity, we construct a modality selector (or disambiguator) network, and this model gets substantially lower accuracy on our challenge set, compared to existing datasets, indicating that our questions are more ambiguous. By analyzing this model, we investigate which words in the question are indicative of the modality. Next, we construct a simple baseline ManyModalQA model, which, based on the prediction from the modality selector, fires a corresponding pre-trained state-of-the-art unimodal QA model. We focus on providing the community with a new manymodal evaluation set and only provide a fine-tuning set, with the expectation that existing datasets and approaches will be transferred for most of the training, to encourage low-resource generalization without large, monolithic training sets for each new task. There is a significant gap between our baseline models and human performance; therefore, we hope that this challenge encourages research in end-to-end modality disambiguation and multimodal QA models, as well as transfer learning. Code and data available at: https://github.com/hannandarryl/ManyModalQA

Deep Sparse Coding for Invariant Multimodal Halle Berry Neurons

Deep feed-forward convolutional neural networks (CNNs) have become ubiquitous in virtually all machine learning and computer vision challenges; however, advancements in CNNs have arguably reached an engineering saturation point where incremental novelty results in minor performance gains. Although there is evidence that object classification has reached human levels on narrowly defined tasks, for general applications, the biological visual system is far superior to that of any computer. Research reveals there are numerous missing components in feed-forward deep neural networks that are critical in mammalian vision. The brain does not work solely in a feed-forward fashion, but rather all of the neurons are in competition with each other; neurons are integrating information in a bottom up and top down fashion and incorporating expectation and feedback in the modeling process. Furthermore, our visual cortex is working in tandem with our parietal lobe, integrating sensory information from various modalities. In our work, we sought to improve upon the standard feed-forward deep learning model by augmenting them with biologically inspired concepts of sparsity, top-down feedback, and lateral inhibition. We define our model as a sparse coding problem using hierarchical layers. We solve the sparse coding problem with an additional top-down feedback error driving the dynamics of the neural network. While building and observing the behavior of our model, we were fascinated that multimodal, invariant neurons naturally emerged that mimicked, "Halle Berry neurons" found in the human brain. Furthermore, our sparse representation of multimodal signals demonstrates qualitative and quantitative superiority to the standard feed-forward joint embedding in common vision and machine learning tasks.